Global dissemination of a single mutation conferring white pericarp in rice

Here we report that the change from the red seeds of wild rice to the white seeds of cultivated rice (Oryza sativa) resulted from the strong selective sweep of a single mutation, a frame-shift deletion within the Rc gene that is found in 97.9% of white rice varieties today. A second mutation, also w...

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Autores principales: Sweeney, Megan T., Thomson, Michael J., Cho, Yong Gu, Park, Yong Jin, Williamson, Scott H., Bustamante, Carlos D., McCouch, Susan R.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://hdl.handle.net/10568/166426
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author Sweeney, Megan T.
Thomson, Michael J.
Cho, Yong Gu
Park, Yong Jin
Williamson, Scott H.
Bustamante, Carlos D.
McCouch, Susan R.
author_browse Bustamante, Carlos D.
Cho, Yong Gu
McCouch, Susan R.
Park, Yong Jin
Sweeney, Megan T.
Thomson, Michael J.
Williamson, Scott H.
author_facet Sweeney, Megan T.
Thomson, Michael J.
Cho, Yong Gu
Park, Yong Jin
Williamson, Scott H.
Bustamante, Carlos D.
McCouch, Susan R.
author_sort Sweeney, Megan T.
collection Repository of Agricultural Research Outputs (CGSpace)
description Here we report that the change from the red seeds of wild rice to the white seeds of cultivated rice (Oryza sativa) resulted from the strong selective sweep of a single mutation, a frame-shift deletion within the Rc gene that is found in 97.9% of white rice varieties today. A second mutation, also within Rc, is present in less than 3% of white accessions surveyed. Haplotype analysis revealed that the predominant mutation originated in the japonica subspecies and crossed both geographic and sterility barriers to move into the indica subspecies. A little less than one Mb of japonica DNA hitchhiked with the rc allele into most indica varieties, suggesting that other linked domestication alleles may have been transferred from japonica to indica along with white pericarp color. Our finding provides evidence of active cultural exchange among ancient farmers over the course of rice domestication coupled with very strong, positive selection for a single white allele in both subspecies of O. sativa
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spelling CGSpace1664262025-05-14T10:24:19Z Global dissemination of a single mutation conferring white pericarp in rice Sweeney, Megan T. Thomson, Michael J. Cho, Yong Gu Park, Yong Jin Williamson, Scott H. Bustamante, Carlos D. McCouch, Susan R. alleles colour dna genes genetic analysis haplotypes mutants mutations pericarp seeds Here we report that the change from the red seeds of wild rice to the white seeds of cultivated rice (Oryza sativa) resulted from the strong selective sweep of a single mutation, a frame-shift deletion within the Rc gene that is found in 97.9% of white rice varieties today. A second mutation, also within Rc, is present in less than 3% of white accessions surveyed. Haplotype analysis revealed that the predominant mutation originated in the japonica subspecies and crossed both geographic and sterility barriers to move into the indica subspecies. A little less than one Mb of japonica DNA hitchhiked with the rc allele into most indica varieties, suggesting that other linked domestication alleles may have been transferred from japonica to indica along with white pericarp color. Our finding provides evidence of active cultural exchange among ancient farmers over the course of rice domestication coupled with very strong, positive selection for a single white allele in both subspecies of O. sativa 2007-08-10 2024-12-19T12:56:15Z 2024-12-19T12:56:15Z Journal Article https://hdl.handle.net/10568/166426 en Open Access Public Library of Science Sweeney, Megan T; Thomson, Michael J; Cho, Yong Gu; Park, Yong Jin; Williamson, Scott H; Bustamante, Carlos D and McCouch, Susan R. 2007. Global dissemination of a single mutation conferring white pericarp in rice. PLoS Genet, Volume 3 no. 8 p. e133
spellingShingle alleles
colour
dna
genes
genetic analysis
haplotypes
mutants
mutations
pericarp
seeds
Sweeney, Megan T.
Thomson, Michael J.
Cho, Yong Gu
Park, Yong Jin
Williamson, Scott H.
Bustamante, Carlos D.
McCouch, Susan R.
Global dissemination of a single mutation conferring white pericarp in rice
title Global dissemination of a single mutation conferring white pericarp in rice
title_full Global dissemination of a single mutation conferring white pericarp in rice
title_fullStr Global dissemination of a single mutation conferring white pericarp in rice
title_full_unstemmed Global dissemination of a single mutation conferring white pericarp in rice
title_short Global dissemination of a single mutation conferring white pericarp in rice
title_sort global dissemination of a single mutation conferring white pericarp in rice
topic alleles
colour
dna
genes
genetic analysis
haplotypes
mutants
mutations
pericarp
seeds
url https://hdl.handle.net/10568/166426
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