Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance

Rice is a salt-sensitive species with enormous genetic variation for salt tolerance hidden in its germplasm pool. The EcoTILLING technique allows us to assign haplotypes, thus reducing the number of accessions to be sequenced, becoming a cost-effective, time-saving and high-throughput method, ideal...

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Autores principales: Negrão, S., Almadanim, C., Pires, I., McNally, K.L., Oliveira, M.M.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Cambridge University Press 2011
Materias:
Acceso en línea:https://hdl.handle.net/10568/165890
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author Negrão, S.
Almadanim, C.
Pires, I.
McNally, K.L.
Oliveira, M.M.
author_browse Almadanim, C.
McNally, K.L.
Negrão, S.
Oliveira, M.M.
Pires, I.
author_facet Negrão, S.
Almadanim, C.
Pires, I.
McNally, K.L.
Oliveira, M.M.
author_sort Negrão, S.
collection Repository of Agricultural Research Outputs (CGSpace)
description Rice is a salt-sensitive species with enormous genetic variation for salt tolerance hidden in its germplasm pool. The EcoTILLING technique allows us to assign haplotypes, thus reducing the number of accessions to be sequenced, becoming a cost-effective, time-saving and high-throughput method, ideal to be used in laboratories with limited financial resources. Aiming to find alleles associated with salinity tolerance, we are currently using the EcoTILLING technique to detect single nucleotide polymorphisms (SNPs) and small indels across 375 germplasm accessions representing the diversity available in domesticated rice. We are targeting several genes known to be involved in salt stress signal transduction (OsCPK17) or tolerance mechanisms (SalT). So far, we found a total of 15 and 23 representative SNPs or indels in OsCPK17 and SalT, respectively. These natural allelic variants are mostly located in 3′-untranslated region, thus opening a new path for studying their potential contribution to the regulation of gene expression and possible role in salt tolerance.
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spelling CGSpace1658902025-05-14T10:40:00Z Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance Negrão, S. Almadanim, C. Pires, I. McNally, K.L. Oliveira, M.M. alleles gene expression genes genetic markers genetic resources genetic variation germplasm haplotypes salinity salt salt tolerance signal transduction single nucleotide polymorphism stress Rice is a salt-sensitive species with enormous genetic variation for salt tolerance hidden in its germplasm pool. The EcoTILLING technique allows us to assign haplotypes, thus reducing the number of accessions to be sequenced, becoming a cost-effective, time-saving and high-throughput method, ideal to be used in laboratories with limited financial resources. Aiming to find alleles associated with salinity tolerance, we are currently using the EcoTILLING technique to detect single nucleotide polymorphisms (SNPs) and small indels across 375 germplasm accessions representing the diversity available in domesticated rice. We are targeting several genes known to be involved in salt stress signal transduction (OsCPK17) or tolerance mechanisms (SalT). So far, we found a total of 15 and 23 representative SNPs or indels in OsCPK17 and SalT, respectively. These natural allelic variants are mostly located in 3′-untranslated region, thus opening a new path for studying their potential contribution to the regulation of gene expression and possible role in salt tolerance. 2011-07 2024-12-19T12:55:36Z 2024-12-19T12:55:36Z Journal Article https://hdl.handle.net/10568/165890 en Cambridge University Press Negrão, S.; Almadanim, C.; Pires, I.; McNally, K. L. and Oliveira, M. M. 2011. Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance. Plant Genet. Res., Volume 9 no. 2 p. 300-304
spellingShingle alleles
gene expression
genes
genetic markers
genetic resources
genetic variation
germplasm
haplotypes
salinity
salt
salt tolerance
signal transduction
single nucleotide polymorphism
stress
Negrão, S.
Almadanim, C.
Pires, I.
McNally, K.L.
Oliveira, M.M.
Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title_full Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title_fullStr Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title_full_unstemmed Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title_short Use of EcoTILLING to identify natural allelic variants of rice candidate genes involved in salinity tolerance
title_sort use of ecotilling to identify natural allelic variants of rice candidate genes involved in salinity tolerance
topic alleles
gene expression
genes
genetic markers
genetic resources
genetic variation
germplasm
haplotypes
salinity
salt
salt tolerance
signal transduction
single nucleotide polymorphism
stress
url https://hdl.handle.net/10568/165890
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