Lateral transfers of large DNA fragments spread functional genes among grasses
A fundamental tenet of multicellular eukaryotic evolution is that vertical inheritance is paramount, with natural selection acting on genetic variants transferred from parents to offspring. This lineal process means that an organism’s adaptive potential can be restricted by its evolutionary history,...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
National Academy of Sciences
2019
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| Acceso en línea: | https://hdl.handle.net/10568/164729 |
| _version_ | 1855513766202966016 |
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| author | Dunning, Luke T. Olofsson, Jill K. Parisod, Christian Choudhury, Rimjhim Roy Moreno-Villena, Jose J. Yang, Yang Dionora, Jacqueline Quick, W. Paul Park, Minkyu Bennetzen, Jeffrey L. Besnard, Guillaume Nosil, Patrik Osborne, Colin P. Christin, Pascal-Antoine |
| author_browse | Bennetzen, Jeffrey L. Besnard, Guillaume Choudhury, Rimjhim Roy Christin, Pascal-Antoine Dionora, Jacqueline Dunning, Luke T. Moreno-Villena, Jose J. Nosil, Patrik Olofsson, Jill K. Osborne, Colin P. Parisod, Christian Park, Minkyu Quick, W. Paul Yang, Yang |
| author_facet | Dunning, Luke T. Olofsson, Jill K. Parisod, Christian Choudhury, Rimjhim Roy Moreno-Villena, Jose J. Yang, Yang Dionora, Jacqueline Quick, W. Paul Park, Minkyu Bennetzen, Jeffrey L. Besnard, Guillaume Nosil, Patrik Osborne, Colin P. Christin, Pascal-Antoine |
| author_sort | Dunning, Luke T. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | A fundamental tenet of multicellular eukaryotic evolution is that vertical inheritance is paramount, with natural selection acting on genetic variants transferred from parents to offspring. This lineal process means that an organism’s adaptive potential can be restricted by its evolutionary history, the amount of standing genetic variation, and its mutation rate. Lateral gene transfer (LGT) theoretically provides a mechanism to bypass many of these limitations, but the evolutionary importance and frequency of this process in multicellular eukaryotes, such as plants, remains debated. We address this issue by assembling a chromosome-level genome for the grass Alloteropsis semialata , a species surmised to exhibit two LGTs, and screen it for other grass-to-grass LGTs using genomic data from 146 other grass species. Through stringent phylogenomic analyses, we discovered 57 additional LGTs in the A. semialata nuclear genome, involving at least nine different donor species. The LGTs are clustered in 23 laterally acquired genomic fragments that are up to 170 kb long and have accumulated during the diversification of Alloteropsis. The majority of the 59 LGTs in A. semialata are expressed, and we show that they have added functions to the recipient genome. Functional LGTs were further detected in the genomes of five other grass species, demonstrating that this process is likely widespread in this globally important group of plants. LGT therefore appears to represent a potent evolutionary force capable of spreading functional genes among distantly related grass species. |
| format | Journal Article |
| id | CGSpace164729 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | National Academy of Sciences |
| publisherStr | National Academy of Sciences |
| record_format | dspace |
| spelling | CGSpace1647292025-12-08T09:54:28Z Lateral transfers of large DNA fragments spread functional genes among grasses Dunning, Luke T. Olofsson, Jill K. Parisod, Christian Choudhury, Rimjhim Roy Moreno-Villena, Jose J. Yang, Yang Dionora, Jacqueline Quick, W. Paul Park, Minkyu Bennetzen, Jeffrey L. Besnard, Guillaume Nosil, Patrik Osborne, Colin P. Christin, Pascal-Antoine A fundamental tenet of multicellular eukaryotic evolution is that vertical inheritance is paramount, with natural selection acting on genetic variants transferred from parents to offspring. This lineal process means that an organism’s adaptive potential can be restricted by its evolutionary history, the amount of standing genetic variation, and its mutation rate. Lateral gene transfer (LGT) theoretically provides a mechanism to bypass many of these limitations, but the evolutionary importance and frequency of this process in multicellular eukaryotes, such as plants, remains debated. We address this issue by assembling a chromosome-level genome for the grass Alloteropsis semialata , a species surmised to exhibit two LGTs, and screen it for other grass-to-grass LGTs using genomic data from 146 other grass species. Through stringent phylogenomic analyses, we discovered 57 additional LGTs in the A. semialata nuclear genome, involving at least nine different donor species. The LGTs are clustered in 23 laterally acquired genomic fragments that are up to 170 kb long and have accumulated during the diversification of Alloteropsis. The majority of the 59 LGTs in A. semialata are expressed, and we show that they have added functions to the recipient genome. Functional LGTs were further detected in the genomes of five other grass species, demonstrating that this process is likely widespread in this globally important group of plants. LGT therefore appears to represent a potent evolutionary force capable of spreading functional genes among distantly related grass species. 2019-03-05 2024-12-19T12:54:14Z 2024-12-19T12:54:14Z Journal Article https://hdl.handle.net/10568/164729 en Open Access National Academy of Sciences Dunning, Luke T.; Olofsson, Jill K.; Parisod, Christian; Choudhury, Rimjhim Roy; Moreno-Villena, Jose J.; Yang, Yang; Dionora, Jacqueline; Quick, W. Paul; Park, Minkyu; Bennetzen, Jeffrey L.; Besnard, Guillaume; Nosil, Patrik; Osborne, Colin P. and Christin, Pascal-Antoine. 2019. Lateral transfers of large DNA fragments spread functional genes among grasses. Proc. Natl. Acad. Sci. U.S.A., Volume 116 no. 10 p. 4416-4425 |
| spellingShingle | Dunning, Luke T. Olofsson, Jill K. Parisod, Christian Choudhury, Rimjhim Roy Moreno-Villena, Jose J. Yang, Yang Dionora, Jacqueline Quick, W. Paul Park, Minkyu Bennetzen, Jeffrey L. Besnard, Guillaume Nosil, Patrik Osborne, Colin P. Christin, Pascal-Antoine Lateral transfers of large DNA fragments spread functional genes among grasses |
| title | Lateral transfers of large DNA fragments spread functional genes among grasses |
| title_full | Lateral transfers of large DNA fragments spread functional genes among grasses |
| title_fullStr | Lateral transfers of large DNA fragments spread functional genes among grasses |
| title_full_unstemmed | Lateral transfers of large DNA fragments spread functional genes among grasses |
| title_short | Lateral transfers of large DNA fragments spread functional genes among grasses |
| title_sort | lateral transfers of large dna fragments spread functional genes among grasses |
| url | https://hdl.handle.net/10568/164729 |
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