Analysis of differential gene expression and alternative splicing is significantly influenced by choice of reference genome

RNA-seq analysis has enabled the evaluation of transcriptional changes in many species including nonmodel organisms. However, in most species only a single reference genome is available and RNA-seq reads from highly divergent varieties are typically aligned to this reference. Here, we quantify the i...

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Detalles Bibliográficos
Autores principales: Slabaugh, Erin, Desai, Jigar S., Sartor, Ryan C., Lawas, Lovely Mae F., Jagadish, Krishna S.V., Doherty, Colleen J.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Cold Spring Harbor Laboratory 2019
Acceso en línea:https://hdl.handle.net/10568/164713

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