CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects
Several plant pathogens severely affect crop yield and quality, thereby threatening global food security. In order to cope with this challenge, genetic improvement of plant disease resistance is required for sustainable agricultural production, for which conventional breeding is unlikely to do enoug...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Oxford University Press
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/164567 |
| _version_ | 1855521711853666304 |
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| author | Ahmad, Shakeel Wei, Xiangjin Sheng, Zhonghua Hu, Peisong Tang, Shaoqing |
| author_browse | Ahmad, Shakeel Hu, Peisong Sheng, Zhonghua Tang, Shaoqing Wei, Xiangjin |
| author_facet | Ahmad, Shakeel Wei, Xiangjin Sheng, Zhonghua Hu, Peisong Tang, Shaoqing |
| author_sort | Ahmad, Shakeel |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Several plant pathogens severely affect crop yield and quality, thereby threatening global food security. In order to cope with this challenge, genetic improvement of plant disease resistance is required for sustainable agricultural production, for which conventional breeding is unlikely to do enough. Luckily, genome editing systems that particularly clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9) has revolutionized crop improvement by enabling robust and precise targeted genome modifications. It paves the way towards new methods for genetic improvement of plant disease resistance and accelerates resistance breeding. In this review, the challenges, limitations and prospects for conventional breeding and the applications of CRISPR/Cas9 system for the development of transgene-free disease-resistant crops are discussed. |
| format | Journal Article |
| id | CGSpace164567 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Oxford University Press |
| publisherStr | Oxford University Press |
| record_format | dspace |
| spelling | CGSpace1645672026-01-06T12:03:45Z CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects Ahmad, Shakeel Wei, Xiangjin Sheng, Zhonghua Hu, Peisong Tang, Shaoqing general medicine Several plant pathogens severely affect crop yield and quality, thereby threatening global food security. In order to cope with this challenge, genetic improvement of plant disease resistance is required for sustainable agricultural production, for which conventional breeding is unlikely to do enough. Luckily, genome editing systems that particularly clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9) has revolutionized crop improvement by enabling robust and precise targeted genome modifications. It paves the way towards new methods for genetic improvement of plant disease resistance and accelerates resistance breeding. In this review, the challenges, limitations and prospects for conventional breeding and the applications of CRISPR/Cas9 system for the development of transgene-free disease-resistant crops are discussed. 2020-01-22 2024-12-19T12:54:02Z 2024-12-19T12:54:02Z Journal Article https://hdl.handle.net/10568/164567 en Oxford University Press Tang, Shaoqing. 2020. CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects. Briefings in Functional Genomics, Volume 19 no. 1 p. 26-39 |
| spellingShingle | general medicine Ahmad, Shakeel Wei, Xiangjin Sheng, Zhonghua Hu, Peisong Tang, Shaoqing CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title | CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title_full | CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title_fullStr | CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title_full_unstemmed | CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title_short | CRISPR/Cas9 for development of disease resistance in plants: recent progress, limitations and future prospects |
| title_sort | crispr cas9 for development of disease resistance in plants recent progress limitations and future prospects |
| topic | general medicine |
| url | https://hdl.handle.net/10568/164567 |
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