Unraveling candidate genomic regions responsible for delayed leaf senescence in rice

Photosynthates generated after heading contributes to 60% - 80% of grain yield in rice. Delay in leaf senescence can contribute to a long grain-filling period and thereby increased yield. The objective of this study was to identify genomic region(s) responsible for delayed leaf senescence (DLS) and...

Full description

Bibliographic Details
Main Authors: Singh, Uma Maheshwar, Sinha, Pallavi, Dixit, Shilpi, Abbai, Ragavendran, Venkateshwarlu, Challa, Chitikineni, Annapurna, Singh, Vikas Kumar, Varshney, Rajeev K., Kumar, Arvind
Format: Journal Article
Language:Inglés
Published: Public Library of Science 2020
Subjects:
Online Access:https://hdl.handle.net/10568/164414
_version_ 1855540796054306816
author Singh, Uma Maheshwar
Sinha, Pallavi
Dixit, Shilpi
Abbai, Ragavendran
Venkateshwarlu, Challa
Chitikineni, Annapurna
Singh, Vikas Kumar
Varshney, Rajeev K.
Kumar, Arvind
author_browse Abbai, Ragavendran
Chitikineni, Annapurna
Dixit, Shilpi
Kumar, Arvind
Singh, Uma Maheshwar
Singh, Vikas Kumar
Sinha, Pallavi
Varshney, Rajeev K.
Venkateshwarlu, Challa
author_facet Singh, Uma Maheshwar
Sinha, Pallavi
Dixit, Shilpi
Abbai, Ragavendran
Venkateshwarlu, Challa
Chitikineni, Annapurna
Singh, Vikas Kumar
Varshney, Rajeev K.
Kumar, Arvind
author_sort Singh, Uma Maheshwar
collection Repository of Agricultural Research Outputs (CGSpace)
description Photosynthates generated after heading contributes to 60% - 80% of grain yield in rice. Delay in leaf senescence can contribute to a long grain-filling period and thereby increased yield. The objective of this study was to identify genomic region(s) responsible for delayed leaf senescence (DLS) and validate the role of underlying candidate genes in controlling target traits. 302 BC2F4 backcross-derived lines (BILs) developed from a cross between Swarna and Moroberekan were phenotyped for two seasons (DS2016 and WS2017) for chlorophyll content and yield parameters. KASPar-SNP assays based genotyping data with 193 SNPs of mapping population was used to identify the targeted genomic region(s). Significant positive correlation was observed between the two most important determinants of DLS traits viz., RDCF (reduced decline degree of chlorophyll content of flag leaf) and RDCS (reduced decline degree of chlorophyll content of second leaf) with plant height (PH), grain number per panicle (GPN), panicle length (PL), number of tiller (NT) and grain yield (GY). A total of 41 and 29 QTLs with phenotypic variance (PVE) ranging from 8.2 to 25.1% were detected for six DLS traits during DS2016 and WS2017, respectively. Out of these identified QTLs, 19 were considered as stable QTLs detected across seasons. 17 of the identified stable QTLs were found to be novel. In-silico analysis revealed five key genes regulating chlorophyll metabolism. Expression analysis of these genes confirmed their strong association with the senescence pattern in leaf tissue of parents as well as selected phenotypically extreme lines. The identified stable QTLs regulating DLS traits and validation of potential candidate genes provides insight into genetic basis of delayed senescence and is expected to contribute in enhancing grain yield through genomics-assisted breeding (GAB).
format Journal Article
id CGSpace164414
institution CGIAR Consortium
language Inglés
publishDate 2020
publishDateRange 2020
publishDateSort 2020
publisher Public Library of Science
publisherStr Public Library of Science
record_format dspace
spelling CGSpace1644142025-01-24T14:20:50Z Unraveling candidate genomic regions responsible for delayed leaf senescence in rice Singh, Uma Maheshwar Sinha, Pallavi Dixit, Shilpi Abbai, Ragavendran Venkateshwarlu, Challa Chitikineni, Annapurna Singh, Vikas Kumar Varshney, Rajeev K. Kumar, Arvind general agricultural and biological sciences general biochemistry genetics and molecular biology general medicine Photosynthates generated after heading contributes to 60% - 80% of grain yield in rice. Delay in leaf senescence can contribute to a long grain-filling period and thereby increased yield. The objective of this study was to identify genomic region(s) responsible for delayed leaf senescence (DLS) and validate the role of underlying candidate genes in controlling target traits. 302 BC2F4 backcross-derived lines (BILs) developed from a cross between Swarna and Moroberekan were phenotyped for two seasons (DS2016 and WS2017) for chlorophyll content and yield parameters. KASPar-SNP assays based genotyping data with 193 SNPs of mapping population was used to identify the targeted genomic region(s). Significant positive correlation was observed between the two most important determinants of DLS traits viz., RDCF (reduced decline degree of chlorophyll content of flag leaf) and RDCS (reduced decline degree of chlorophyll content of second leaf) with plant height (PH), grain number per panicle (GPN), panicle length (PL), number of tiller (NT) and grain yield (GY). A total of 41 and 29 QTLs with phenotypic variance (PVE) ranging from 8.2 to 25.1% were detected for six DLS traits during DS2016 and WS2017, respectively. Out of these identified QTLs, 19 were considered as stable QTLs detected across seasons. 17 of the identified stable QTLs were found to be novel. In-silico analysis revealed five key genes regulating chlorophyll metabolism. Expression analysis of these genes confirmed their strong association with the senescence pattern in leaf tissue of parents as well as selected phenotypically extreme lines. The identified stable QTLs regulating DLS traits and validation of potential candidate genes provides insight into genetic basis of delayed senescence and is expected to contribute in enhancing grain yield through genomics-assisted breeding (GAB). 2020-10-15 2024-12-19T12:53:51Z 2024-12-19T12:53:51Z Journal Article https://hdl.handle.net/10568/164414 en Open Access Public Library of Science Singh, Uma Maheshwar; Sinha, Pallavi; Dixit, Shilpi; Abbai, Ragavendran; Venkateshwarlu, Challa; Chitikineni, Annapurna; Singh, Vikas Kumar; Varshney, Rajeev K. and Kumar, Arvind. 2020. Unraveling candidate genomic regions responsible for delayed leaf senescence in rice. PLoS ONE, Volume 15 no. 10 p. e0240591
spellingShingle general agricultural and biological sciences general biochemistry
genetics and molecular biology general medicine
Singh, Uma Maheshwar
Sinha, Pallavi
Dixit, Shilpi
Abbai, Ragavendran
Venkateshwarlu, Challa
Chitikineni, Annapurna
Singh, Vikas Kumar
Varshney, Rajeev K.
Kumar, Arvind
Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title_full Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title_fullStr Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title_full_unstemmed Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title_short Unraveling candidate genomic regions responsible for delayed leaf senescence in rice
title_sort unraveling candidate genomic regions responsible for delayed leaf senescence in rice
topic general agricultural and biological sciences general biochemistry
genetics and molecular biology general medicine
url https://hdl.handle.net/10568/164414
work_keys_str_mv AT singhumamaheshwar unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT sinhapallavi unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT dixitshilpi unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT abbairagavendran unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT venkateshwarluchalla unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT chitikineniannapurna unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT singhvikaskumar unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT varshneyrajeevk unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice
AT kumararvind unravelingcandidategenomicregionsresponsiblefordelayedleafsenescenceinrice