The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia

Bovine tuberculosis in domestic livestock such as cattle is an economically important disease with zoonotic potential, particularly in countries with emerging economies. We discuss the findings of recent epidemiological and immunological studies conducted in Ethiopia on host susceptibility differenc...

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Autores principales: Vordermeier, M., Ameni, G., Berg, S., Bishop, Richard P., Robertson, B.D., Aseffa, A., Hewinson, R.G., Young, D.B.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://hdl.handle.net/10568/16437
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author Vordermeier, M.
Ameni, G.
Berg, S.
Bishop, Richard P.
Robertson, B.D.
Aseffa, A.
Hewinson, R.G.
Young, D.B.
author_browse Ameni, G.
Aseffa, A.
Berg, S.
Bishop, Richard P.
Hewinson, R.G.
Robertson, B.D.
Vordermeier, M.
Young, D.B.
author_facet Vordermeier, M.
Ameni, G.
Berg, S.
Bishop, Richard P.
Robertson, B.D.
Aseffa, A.
Hewinson, R.G.
Young, D.B.
author_sort Vordermeier, M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Bovine tuberculosis in domestic livestock such as cattle is an economically important disease with zoonotic potential, particularly in countries with emerging economies. We discuss the findings of recent epidemiological and immunological studies conducted in Ethiopia on host susceptibility differences between native zebu and the exotic Holstein–Friesian cattle that are increasingly part of the Ethiopian National herd, due to the drive to increase milk yields. These findings support the hypothesis that native Zebu cattle are more resistant to bovine tuberculosis. We also summarise the results of experimental infections that support the epidemiological data, and of laboratory experiments that suggest a role for the innate immune response, and in particular interleukin-6, in the outcome of bovine tuberculosis infection.
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spelling CGSpace164372025-06-13T04:20:23Z The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia Vordermeier, M. Ameni, G. Berg, S. Bishop, Richard P. Robertson, B.D. Aseffa, A. Hewinson, R.G. Young, D.B. tuberculosis animal diseases cattle Bovine tuberculosis in domestic livestock such as cattle is an economically important disease with zoonotic potential, particularly in countries with emerging economies. We discuss the findings of recent epidemiological and immunological studies conducted in Ethiopia on host susceptibility differences between native zebu and the exotic Holstein–Friesian cattle that are increasingly part of the Ethiopian National herd, due to the drive to increase milk yields. These findings support the hypothesis that native Zebu cattle are more resistant to bovine tuberculosis. We also summarise the results of experimental infections that support the epidemiological data, and of laboratory experiments that suggest a role for the innate immune response, and in particular interleukin-6, in the outcome of bovine tuberculosis infection. 2012-05 2012-02-06T19:53:35Z 2012-02-06T19:53:35Z Journal Article https://hdl.handle.net/10568/16437 en Open Access Elsevier Vordermeier, M., Ameni, G., Berg, S., Bishop, R., Robertson, B.D., Aseffa, A., Hewinson, R.G. and Young, D.B. 2012. The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia. Comparative Immunology, Microbiology and Infectious Diseases 35(3): 227-232.
spellingShingle tuberculosis
animal diseases
cattle
Vordermeier, M.
Ameni, G.
Berg, S.
Bishop, Richard P.
Robertson, B.D.
Aseffa, A.
Hewinson, R.G.
Young, D.B.
The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title_full The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title_fullStr The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title_full_unstemmed The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title_short The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia
title_sort influence of cattle breed on susceptibility to bovine tuberculosis in ethiopia
topic tuberculosis
animal diseases
cattle
url https://hdl.handle.net/10568/16437
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