Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health
Whole grain cereals are a good source of nutrients. Several cutting-edge metabolomic platforms have been deployed to identify various phenolic compounds and enhance cereal bioactive bioavailability. A diet rich in cereal phenolics may modify the microbial composition, support gut homeostasis, and in...
| Autores principales: | , , , , |
|---|---|
| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/164037 |
| _version_ | 1855534007163289600 |
|---|---|
| author | Tiozon, Rhowell Jr. N. Sartagoda, Kristel June D. Serrano, Luster May N. Fernie, Alisdair R. Sreenivasulu, Nese |
| author_browse | Fernie, Alisdair R. Sartagoda, Kristel June D. Serrano, Luster May N. Sreenivasulu, Nese Tiozon, Rhowell Jr. N. |
| author_facet | Tiozon, Rhowell Jr. N. Sartagoda, Kristel June D. Serrano, Luster May N. Fernie, Alisdair R. Sreenivasulu, Nese |
| author_sort | Tiozon, Rhowell Jr. N. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Whole grain cereals are a good source of nutrients. Several cutting-edge metabolomic platforms have been deployed to identify various phenolic compounds and enhance cereal bioactive bioavailability. A diet rich in cereal phenolics may modify the microbial composition, support gut homeostasis, and increase gut health, thereby lowering the risk of non-communicable illness. In this work, we reviewed current metabolomic breakthroughs in cereal phenolic profiling and their effects on human health via gut microbiota modulation. We argue that the information presented in this paper will assist in the development of nutritionally superior cereal breeds and functional foods. Most cereal grains contain ferulic acid derivatives, caffeoyl glycerides, and feruloyl and coumaroyl esters. While there has been significant progress in discovering novel phenolic compounds in cereals, quantifying these molecules, and translating their therapeutic effects from animal model systems to humans remains a challenge. To this end, metabolomics, and other high-throughput-omics-based platforms must be integrated to further examine the structure and functionality of phenolic metabolites to breed nutritionally rich cereals as well as map their influence on human health benefits. Rare alleles must be introduced to improve bioactive content in cereal grains while maintaining yield. Following that, these exceptional varieties must be effectively processed to maximize phenolic bioavailability. |
| format | Journal Article |
| id | CGSpace164037 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace1640372024-12-19T14:13:12Z Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health Tiozon, Rhowell Jr. N. Sartagoda, Kristel June D. Serrano, Luster May N. Fernie, Alisdair R. Sreenivasulu, Nese food science biotechnology Whole grain cereals are a good source of nutrients. Several cutting-edge metabolomic platforms have been deployed to identify various phenolic compounds and enhance cereal bioactive bioavailability. A diet rich in cereal phenolics may modify the microbial composition, support gut homeostasis, and increase gut health, thereby lowering the risk of non-communicable illness. In this work, we reviewed current metabolomic breakthroughs in cereal phenolic profiling and their effects on human health via gut microbiota modulation. We argue that the information presented in this paper will assist in the development of nutritionally superior cereal breeds and functional foods. Most cereal grains contain ferulic acid derivatives, caffeoyl glycerides, and feruloyl and coumaroyl esters. While there has been significant progress in discovering novel phenolic compounds in cereals, quantifying these molecules, and translating their therapeutic effects from animal model systems to humans remains a challenge. To this end, metabolomics, and other high-throughput-omics-based platforms must be integrated to further examine the structure and functionality of phenolic metabolites to breed nutritionally rich cereals as well as map their influence on human health benefits. Rare alleles must be introduced to improve bioactive content in cereal grains while maintaining yield. Following that, these exceptional varieties must be effectively processed to maximize phenolic bioavailability. 2022-09 2024-12-19T12:53:21Z 2024-12-19T12:53:21Z Journal Article https://hdl.handle.net/10568/164037 en Open Access Elsevier Tiozon, Rhowell Jr. N.; Sartagoda, Kristel June D.; Serrano, Luster May N.; Fernie, Alisdair R. and Sreenivasulu, Nese. 2022. Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health. Trends in Food Science and Technology, Volume 127 p. 14-25 |
| spellingShingle | food science biotechnology Tiozon, Rhowell Jr. N. Sartagoda, Kristel June D. Serrano, Luster May N. Fernie, Alisdair R. Sreenivasulu, Nese Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title | Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title_full | Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title_fullStr | Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title_full_unstemmed | Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title_short | Metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| title_sort | metabolomics based inferences to unravel phenolic compound diversity in cereals and its implications for human gut health |
| topic | food science biotechnology |
| url | https://hdl.handle.net/10568/164037 |
| work_keys_str_mv | AT tiozonrhowelljrn metabolomicsbasedinferencestounravelphenoliccompounddiversityincerealsanditsimplicationsforhumanguthealth AT sartagodakristeljuned metabolomicsbasedinferencestounravelphenoliccompounddiversityincerealsanditsimplicationsforhumanguthealth AT serranolustermayn metabolomicsbasedinferencestounravelphenoliccompounddiversityincerealsanditsimplicationsforhumanguthealth AT ferniealisdairr metabolomicsbasedinferencestounravelphenoliccompounddiversityincerealsanditsimplicationsforhumanguthealth AT sreenivasulunese metabolomicsbasedinferencestounravelphenoliccompounddiversityincerealsanditsimplicationsforhumanguthealth |