Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya
Rabies vaccination in domestic dog populations has increased globally in a bid to protect human health. Surveillance efforts, however, are inconsistent in endemic regions such as in sub-Saharan Africa, due to fragmented reporting and limited diagnostic capacity for suspected cases, limiting successf...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Wiley
2025
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/162959 |
| _version_ | 1855525647792734208 |
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| author | Odinga, Christian O. Thomas, Lian F. Wambugu, E. Ferguson, A.W. Fèvre, Eric M. Gibson, A. Hassell, James M. Muloi, Dishon M. Murray, S. Surmat, A. Mwai, P.M. Woodroffe, R. Ngatia, D. Gathura, P.M. Waitumbi, J. Worsley-Tonks, Katherine E.L. |
| author_browse | Ferguson, A.W. Fèvre, Eric M. Gathura, P.M. Gibson, A. Hassell, James M. Muloi, Dishon M. Murray, S. Mwai, P.M. Ngatia, D. Odinga, Christian O. Surmat, A. Thomas, Lian F. Waitumbi, J. Wambugu, E. Woodroffe, R. Worsley-Tonks, Katherine E.L. |
| author_facet | Odinga, Christian O. Thomas, Lian F. Wambugu, E. Ferguson, A.W. Fèvre, Eric M. Gibson, A. Hassell, James M. Muloi, Dishon M. Murray, S. Surmat, A. Mwai, P.M. Woodroffe, R. Ngatia, D. Gathura, P.M. Waitumbi, J. Worsley-Tonks, Katherine E.L. |
| author_sort | Odinga, Christian O. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Rabies vaccination in domestic dog populations has increased globally in a bid to protect human health. Surveillance efforts, however, are inconsistent in endemic regions such as in sub-Saharan Africa, due to fragmented reporting and limited diagnostic capacity for suspected cases, limiting successful monitoring and evaluation of vaccination campaigns. Here, we conducted a pilot study aiming to strengthen rabies surveillance by combining community-based surveillance with field-based diagnostic testing in pastoral and agro-pastoral communities in central Kenya; communities which are frequently marginalised from health systems. During the 6-month pilot study, there were 14 alerts of suspected rabid dogs in the community, of which eight were tested and five diagnostically confirmed as rabid. Two positive samples processed successfully for whole genome sequencing indicated that the rabies variant circulating in central Kenya during the study period belonged to the Africa 1b subclade, which is similar to variants identified in eastern Kenya and Tanzania, suggesting regional transmission. This pilot study indicates that rabies continues to circulate in the region and that community-based surveillance, when combined with enhanced diagnostic testing, can help alleviate underreporting and guide vaccination campaigns. |
| format | Journal Article |
| id | CGSpace162959 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | CGSpace1629592025-02-24T12:33:52Z Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya Odinga, Christian O. Thomas, Lian F. Wambugu, E. Ferguson, A.W. Fèvre, Eric M. Gibson, A. Hassell, James M. Muloi, Dishon M. Murray, S. Surmat, A. Mwai, P.M. Woodroffe, R. Ngatia, D. Gathura, P.M. Waitumbi, J. Worsley-Tonks, Katherine E.L. diagnostic techniques zoonoses rabies disease control one health approach Rabies vaccination in domestic dog populations has increased globally in a bid to protect human health. Surveillance efforts, however, are inconsistent in endemic regions such as in sub-Saharan Africa, due to fragmented reporting and limited diagnostic capacity for suspected cases, limiting successful monitoring and evaluation of vaccination campaigns. Here, we conducted a pilot study aiming to strengthen rabies surveillance by combining community-based surveillance with field-based diagnostic testing in pastoral and agro-pastoral communities in central Kenya; communities which are frequently marginalised from health systems. During the 6-month pilot study, there were 14 alerts of suspected rabid dogs in the community, of which eight were tested and five diagnostically confirmed as rabid. Two positive samples processed successfully for whole genome sequencing indicated that the rabies variant circulating in central Kenya during the study period belonged to the Africa 1b subclade, which is similar to variants identified in eastern Kenya and Tanzania, suggesting regional transmission. This pilot study indicates that rabies continues to circulate in the region and that community-based surveillance, when combined with enhanced diagnostic testing, can help alleviate underreporting and guide vaccination campaigns. 2025-03 2024-12-03T05:10:17Z 2024-12-03T05:10:17Z Journal Article https://hdl.handle.net/10568/162959 en Open Access Wiley Odinga, C.O., Thomas, L.F., Wambugu, E., Ferguson, A.W., Fèvre, E.M., Gibson, A., Hassell, J.M., Muloi, D.M., Murray, S., Surmat, A., Mwai, P.M., Woodroffe, R., Ngatia, D., Gathura, P.M., Waitumbi, J. and Worsley-Tonks, K.E.L. 2025. Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya. Zoonoses and Public Health 72(2): 194–199. |
| spellingShingle | diagnostic techniques zoonoses rabies disease control one health approach Odinga, Christian O. Thomas, Lian F. Wambugu, E. Ferguson, A.W. Fèvre, Eric M. Gibson, A. Hassell, James M. Muloi, Dishon M. Murray, S. Surmat, A. Mwai, P.M. Woodroffe, R. Ngatia, D. Gathura, P.M. Waitumbi, J. Worsley-Tonks, Katherine E.L. Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title | Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title_full | Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title_fullStr | Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title_full_unstemmed | Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title_short | Integrated community-based reporting and field diagnostics for improved rabies surveillance in rural Laikipia, Kenya |
| title_sort | integrated community based reporting and field diagnostics for improved rabies surveillance in rural laikipia kenya |
| topic | diagnostic techniques zoonoses rabies disease control one health approach |
| url | https://hdl.handle.net/10568/162959 |
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