Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia
Background: Peste des petits ruminants (PPR) is a contagious disease caused by the peste des petits ruminants virus (PPRV). The disease poses a significant economic threat to small ruminant production in Ethiopia, particularly to the striving pastoral production system. A cross-sectional study was c...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
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Springer
2024
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| Online Access: | https://hdl.handle.net/10568/155387 |
| _version_ | 1855525627440922624 |
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| author | Kumbe, A. Negussie, H. Getachew, Y. Alemu, Biruk Alemayehu, Gezahegn Girma, S. Sibhatu, D. Emiyu, K. Waktole, H. Leta, S. |
| author_browse | Alemayehu, Gezahegn Alemu, Biruk Emiyu, K. Getachew, Y. Girma, S. Kumbe, A. Leta, S. Negussie, H. Sibhatu, D. Waktole, H. |
| author_facet | Kumbe, A. Negussie, H. Getachew, Y. Alemu, Biruk Alemayehu, Gezahegn Girma, S. Sibhatu, D. Emiyu, K. Waktole, H. Leta, S. |
| author_sort | Kumbe, A. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background: Peste des petits ruminants (PPR) is a contagious disease caused by the peste des petits ruminants virus (PPRV). The disease poses a significant economic threat to small ruminant production in Ethiopia, particularly to the striving pastoral production system. A cross-sectional study was conducted to estimate the seroprevalence and associated risk factors of PPR in the small ruminants of the Borena Zone. A total of 384 serum samples were collected randomly from sheep and goats and examined for the presence of PPRV antibodies using competition enzyme-linked immune sorbent assay (c-ELISA). Additionally, a retrospective analysis of five years of outbreak data was performed to provide insight into the spatial and temporal distribution of the disease.
Results: The seroprevalence of PPRV antibodies in nonvaccinated, vaccinated, and unknown vaccination status of small ruminants in this study was found to be 32.1%, 68.8%, and 45.5%, respectively. Multivariable logistic analysis revealed a statistically significant association between PPRV seropositivity and several factors, including age, animal origin, flock size, and veterinary services status. A retrospective analysis revealed 53 PPR outbreaks in the Borena Zone from 2018 to 2022, exacerbated by low vaccination coverage relative to the at-risk animal population.
Conclusion: The study revealed significant gaps in current vaccination efforts, with herd immunity levels falling below the FAO-WOAH recommended threshold of 80%. Despite Ethiopia’s ambitious goal to eradicate PPR by 2027, the frequent outbreaks and insufficient herd immunity highlight the inadequacy of the existing strategies. To effectively move toward eradication, Ethiopia must align its approach with the global PPR eradication framework, which emphasizes a comprehensive strategy that includes diagnostics, surveillance, prevention, and the establishment of a robust veterinary regulatory system, rather than relying solely on vaccination. Overcoming logistical challenges, improving vaccination coverage, and optimizing the timing of vaccination campaigns, especially in hard-to-reach areas, will be crucial for reducing outbreaks and making progress toward eradication. |
| format | Journal Article |
| id | CGSpace155387 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Springer |
| publisherStr | Springer |
| record_format | dspace |
| spelling | CGSpace1553872025-12-08T10:06:44Z Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia Kumbe, A. Negussie, H. Getachew, Y. Alemu, Biruk Alemayehu, Gezahegn Girma, S. Sibhatu, D. Emiyu, K. Waktole, H. Leta, S. epidemiology peste des petits ruminants Background: Peste des petits ruminants (PPR) is a contagious disease caused by the peste des petits ruminants virus (PPRV). The disease poses a significant economic threat to small ruminant production in Ethiopia, particularly to the striving pastoral production system. A cross-sectional study was conducted to estimate the seroprevalence and associated risk factors of PPR in the small ruminants of the Borena Zone. A total of 384 serum samples were collected randomly from sheep and goats and examined for the presence of PPRV antibodies using competition enzyme-linked immune sorbent assay (c-ELISA). Additionally, a retrospective analysis of five years of outbreak data was performed to provide insight into the spatial and temporal distribution of the disease. Results: The seroprevalence of PPRV antibodies in nonvaccinated, vaccinated, and unknown vaccination status of small ruminants in this study was found to be 32.1%, 68.8%, and 45.5%, respectively. Multivariable logistic analysis revealed a statistically significant association between PPRV seropositivity and several factors, including age, animal origin, flock size, and veterinary services status. A retrospective analysis revealed 53 PPR outbreaks in the Borena Zone from 2018 to 2022, exacerbated by low vaccination coverage relative to the at-risk animal population. Conclusion: The study revealed significant gaps in current vaccination efforts, with herd immunity levels falling below the FAO-WOAH recommended threshold of 80%. Despite Ethiopia’s ambitious goal to eradicate PPR by 2027, the frequent outbreaks and insufficient herd immunity highlight the inadequacy of the existing strategies. To effectively move toward eradication, Ethiopia must align its approach with the global PPR eradication framework, which emphasizes a comprehensive strategy that includes diagnostics, surveillance, prevention, and the establishment of a robust veterinary regulatory system, rather than relying solely on vaccination. Overcoming logistical challenges, improving vaccination coverage, and optimizing the timing of vaccination campaigns, especially in hard-to-reach areas, will be crucial for reducing outbreaks and making progress toward eradication. 2024 2024-10-17T10:27:06Z 2024-10-17T10:27:06Z Journal Article https://hdl.handle.net/10568/155387 en Open Access Springer Kumbe, A., Negussie, H., Getachew, Y., Alemu, B., Alemayehu, G., Girma, S., Sibhatu, D., Emiyu, K., Waktole, H. and Leta, S. 2024. Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia. BMC Veterinary Research 20: 451. |
| spellingShingle | epidemiology peste des petits ruminants Kumbe, A. Negussie, H. Getachew, Y. Alemu, Biruk Alemayehu, Gezahegn Girma, S. Sibhatu, D. Emiyu, K. Waktole, H. Leta, S. Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title | Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title_full | Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title_fullStr | Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title_full_unstemmed | Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title_short | Epidemiology of peste des petits ruminants in selected districts of Borena zone, Ethiopia |
| title_sort | epidemiology of peste des petits ruminants in selected districts of borena zone ethiopia |
| topic | epidemiology peste des petits ruminants |
| url | https://hdl.handle.net/10568/155387 |
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