Mass spectrometry detection of G3m and IGHG3 alleles and follow-up of differential mother and neonate IgG3

Mass spectrometry (MS) analysis for detection of immunoglobulins (IG) of the human IgG3 subclass is described that relies on polymorphic amino acids of the heavy gamma3 chains. IgG3 is the most polymorphic human IgG subclass with thirteen G3m allotypes located on the constant CH2 and CH3 domains of...

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Main Authors:	Dechavanne, Célia, Guillonneau, François, Chiappetta, Giovanni, Sago, Laïla, Lévy, Prisca, Salnot, Virginie, Guitard, Evelyne, Ehrenmann, François, Broussard, Cédric, Chafey, Philippe, Le Port, Agnès, Vinh, Joëlle, Mayeux, Patrick, Dugoujon, Jean-Michel, Lefranc, Marie-Paule, Migot-Nabias, Florence
Format:	Journal Article
Language:	Inglés
Published:	Public Library of Science 2012
Subjects:	mass spectrometry immunoglobulins amino acids
Online Access:	https://hdl.handle.net/10568/153241