Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi

Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely...

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Autores principales: Hurst, Rachel, Siyame, Edwin W. P., Young, Scott D., Chilimba, Allan D.C., Joy, Edward J.M., Black, Colin R., Ander, E. Louise, Watts, Michael J., Chilima, Benson, Gondwe, Jellita, Kang'ombe, Dalitso, Stein, Alexander J., Fairweather-Tait, Susan J., Gibson, Rosalind S., Kalimbira, Alexander A., Broadley, Martin R.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2013
Materias:
Acceso en línea:https://hdl.handle.net/10568/152733
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author Hurst, Rachel
Siyame, Edwin W. P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang'ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
author_browse Ander, E. Louise
Black, Colin R.
Broadley, Martin R.
Chilima, Benson
Chilimba, Allan D.C.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Gondwe, Jellita
Hurst, Rachel
Joy, Edward J.M.
Kalimbira, Alexander A.
Kang'ombe, Dalitso
Siyame, Edwin W. P.
Stein, Alexander J.
Watts, Michael J.
Young, Scott D.
author_facet Hurst, Rachel
Siyame, Edwin W. P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang'ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
author_sort Hurst, Rachel
collection Repository of Agricultural Research Outputs (CGSpace)
description Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely endemic in Malawi based on the Se status of adults consuming food from contrasting soil types. These data are consistent with food balance sheets and composition tables revealing that >80% of the Malawi population is at risk of dietary Se inadequacy. Risk of dietary Se inadequacy is >60% in seven other countries in Southern Africa and 22% across Africa as a whole. Given that most Malawi soils cannot supply sufficient Se to crops for adequate human nutrition, the cost and benefits of interventions to alleviate Se deficiency should be determined; for example, Se-enriched nitrogen fertilisers could be adopted as in Finland.
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spelling CGSpace1527332025-09-25T13:01:37Z Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi Hurst, Rachel Siyame, Edwin W. P. Young, Scott D. Chilimba, Allan D.C. Joy, Edward J.M. Black, Colin R. Ander, E. Louise Watts, Michael J. Chilima, Benson Gondwe, Jellita Kang'ombe, Dalitso Stein, Alexander J. Fairweather-Tait, Susan J. Gibson, Rosalind S. Kalimbira, Alexander A. Broadley, Martin R. selenium trace elements antioxidants deficiency diseases soil types immune system human pathology crops Selenium (Se) is an essential human micronutrient with critical roles in immune functioning and antioxidant defence. Estimates of dietary Se intakes and status are scarce for Africa although crop surveys indicate deficiency is probably widespread in Malawi. Here we show that Se deficiency is likely endemic in Malawi based on the Se status of adults consuming food from contrasting soil types. These data are consistent with food balance sheets and composition tables revealing that >80% of the Malawi population is at risk of dietary Se inadequacy. Risk of dietary Se inadequacy is >60% in seven other countries in Southern Africa and 22% across Africa as a whole. Given that most Malawi soils cannot supply sufficient Se to crops for adequate human nutrition, the cost and benefits of interventions to alleviate Se deficiency should be determined; for example, Se-enriched nitrogen fertilisers could be adopted as in Finland. 2013 2024-10-01T13:55:08Z 2024-10-01T13:55:08Z Journal Article https://hdl.handle.net/10568/152733 en Open Access Springer Hurst, Rachel; Siyame, Edwin W.P.; Young, Scott D.; Chilimba, Allan D.C.; Joy, Edward J.M.; Black, Colin R.; Ander, E. Louise; Watts, Michael J.; Chilima, Benson; Gondwe, Jellita; Kang'ombe, Dalitso; Stein, Alexander J.; Fairweather-Tait, Susan J.; Gibson, Rosalind S.; Kalimbira, Alexander A.; and Broadley, Martin R. 2013. Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi. Scientific Reports 3: 1425. https://doi.org/10.1038/srep01425
spellingShingle selenium
trace elements
antioxidants
deficiency diseases
soil types
immune system
human pathology
crops
Hurst, Rachel
Siyame, Edwin W. P.
Young, Scott D.
Chilimba, Allan D.C.
Joy, Edward J.M.
Black, Colin R.
Ander, E. Louise
Watts, Michael J.
Chilima, Benson
Gondwe, Jellita
Kang'ombe, Dalitso
Stein, Alexander J.
Fairweather-Tait, Susan J.
Gibson, Rosalind S.
Kalimbira, Alexander A.
Broadley, Martin R.
Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_full Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_fullStr Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_full_unstemmed Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_short Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi
title_sort soil type influences human selenium status and underlies widespread selenium deficiency risks in malawi
topic selenium
trace elements
antioxidants
deficiency diseases
soil types
immune system
human pathology
crops
url https://hdl.handle.net/10568/152733
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