Brucella species circulating in smallholder dairy cattle in Tanzania
Brucellosis is a zoonosis caused by bacteria of the genus <i>Brucella</i>, which results in economic losses relating to livestock and threatens public health. A cross-sectional study was conducted to determine the molecular prevalence of <i>Brucella</i> species in smallholder dairy cattle in six reg...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
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MDPI
2024
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/152333 |
| _version_ | 1855520892858138624 |
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| author | Mengele, Isaac J. Akoko, James M. Shirima, G.M. Bwatota, S.F. Motto, S.K. Hernandez-Castro, L.E. Komwihangilo, D.M. Lyatuu, Eliamoni Bronsvoort, B.M. de C. Cook, Elizabeth A.J. |
| author_browse | Akoko, James M. Bronsvoort, B.M. de C. Bwatota, S.F. Cook, Elizabeth A.J. Hernandez-Castro, L.E. Komwihangilo, D.M. Lyatuu, Eliamoni Mengele, Isaac J. Motto, S.K. Shirima, G.M. |
| author_facet | Mengele, Isaac J. Akoko, James M. Shirima, G.M. Bwatota, S.F. Motto, S.K. Hernandez-Castro, L.E. Komwihangilo, D.M. Lyatuu, Eliamoni Bronsvoort, B.M. de C. Cook, Elizabeth A.J. |
| author_sort | Mengele, Isaac J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Brucellosis is a zoonosis caused by bacteria of the genus <i>Brucella</i>, which results in economic losses relating to livestock and threatens public health. A cross-sectional study was conducted to determine the molecular prevalence of <i>Brucella</i> species in smallholder dairy cattle in six regions of Tanzania from July 2019 to October 2020. Dairy cattle (n = 2048) were sampled from 1371 farms. DNA extracted from blood and vaginal swabs was tested for <i>Brucella</i> using qPCR targeting the IS711 gene and positives were tested for the alkB marker for <i>B. abortus</i> and BMEI1172 marker for <i>B. melitensis</i>. The molecular prevalence was 3.5% (95% CI: 2.8–4.4) with the highest prevalence 8.1% (95% CI: 4.6–13.0) in Njombe region. <i>B. melitensis</i> was the predominant species detected (66.2%). Further studies are recommended to understand the source of <i>B. melitensis</i> and its implications for veterinary public health. Livestock keepers should be informed of the risks and biosecurity practices to reduce the introduction and control of <i>Brucella</i>. Cattle and small ruminant vaccination programs could be implemented to control brucellosis in high-risk populations in the country. |
| format | Journal Article |
| id | CGSpace152333 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1523332025-12-08T10:29:22Z Brucella species circulating in smallholder dairy cattle in Tanzania Mengele, Isaac J. Akoko, James M. Shirima, G.M. Bwatota, S.F. Motto, S.K. Hernandez-Castro, L.E. Komwihangilo, D.M. Lyatuu, Eliamoni Bronsvoort, B.M. de C. Cook, Elizabeth A.J. brucellosis cattle dairying zoonoses Brucellosis is a zoonosis caused by bacteria of the genus <i>Brucella</i>, which results in economic losses relating to livestock and threatens public health. A cross-sectional study was conducted to determine the molecular prevalence of <i>Brucella</i> species in smallholder dairy cattle in six regions of Tanzania from July 2019 to October 2020. Dairy cattle (n = 2048) were sampled from 1371 farms. DNA extracted from blood and vaginal swabs was tested for <i>Brucella</i> using qPCR targeting the IS711 gene and positives were tested for the alkB marker for <i>B. abortus</i> and BMEI1172 marker for <i>B. melitensis</i>. The molecular prevalence was 3.5% (95% CI: 2.8–4.4) with the highest prevalence 8.1% (95% CI: 4.6–13.0) in Njombe region. <i>B. melitensis</i> was the predominant species detected (66.2%). Further studies are recommended to understand the source of <i>B. melitensis</i> and its implications for veterinary public health. Livestock keepers should be informed of the risks and biosecurity practices to reduce the introduction and control of <i>Brucella</i>. Cattle and small ruminant vaccination programs could be implemented to control brucellosis in high-risk populations in the country. 2024-09-21 2024-09-23T06:53:11Z 2024-09-23T06:53:11Z Journal Article https://hdl.handle.net/10568/152333 en Open Access MDPI Mengele, I.J., Akoko, J.M., Shirima, G.M., Bwatota, S.F., Motto, S.K., Hernandez-Castro, L.E., Komwihangilo, D.M., Lyatuu, E., Bronsvoort, B.M. de C. and Cook, E.A.J. 2024. <i>Brucella</i> species circulating in smallholder dairy cattle in Tanzania. Pathogens 13(9): 815. |
| spellingShingle | brucellosis cattle dairying zoonoses Mengele, Isaac J. Akoko, James M. Shirima, G.M. Bwatota, S.F. Motto, S.K. Hernandez-Castro, L.E. Komwihangilo, D.M. Lyatuu, Eliamoni Bronsvoort, B.M. de C. Cook, Elizabeth A.J. Brucella species circulating in smallholder dairy cattle in Tanzania |
| title | Brucella species circulating in smallholder dairy cattle in Tanzania |
| title_full | Brucella species circulating in smallholder dairy cattle in Tanzania |
| title_fullStr | Brucella species circulating in smallholder dairy cattle in Tanzania |
| title_full_unstemmed | Brucella species circulating in smallholder dairy cattle in Tanzania |
| title_short | Brucella species circulating in smallholder dairy cattle in Tanzania |
| title_sort | brucella species circulating in smallholder dairy cattle in tanzania |
| topic | brucellosis cattle dairying zoonoses |
| url | https://hdl.handle.net/10568/152333 |
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