Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices

Few data exist on the aetiology of anaemia and Fe deficiency (ID) during early infancy in South Asia. The present study aimed to determine the contribution of ID, infections and feeding practices to anaemia in Bangladeshi infants aged 6–11 months. Baseline data from 1600 infants recruited into a clu...

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Autores principales: Rawat, Rahul, Saha, Kuntal K., Kennedy, Andrew, Rohner, Fabian, Ruel, Marie T., Menon, Purnima
Formato: Journal Article
Lenguaje:Inglés
Publicado: Cambridge University Press 2014
Materias:
Acceso en línea:https://hdl.handle.net/10568/151032
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author Rawat, Rahul
Saha, Kuntal K.
Kennedy, Andrew
Rohner, Fabian
Ruel, Marie T.
Menon, Purnima
author_browse Kennedy, Andrew
Menon, Purnima
Rawat, Rahul
Rohner, Fabian
Ruel, Marie T.
Saha, Kuntal K.
author_facet Rawat, Rahul
Saha, Kuntal K.
Kennedy, Andrew
Rohner, Fabian
Ruel, Marie T.
Menon, Purnima
author_sort Rawat, Rahul
collection Repository of Agricultural Research Outputs (CGSpace)
description Few data exist on the aetiology of anaemia and Fe deficiency (ID) during early infancy in South Asia. The present study aimed to determine the contribution of ID, infections and feeding practices to anaemia in Bangladeshi infants aged 6–11 months. Baseline data from 1600 infants recruited into a cluster-randomised trial testing the effectiveness of micronutrient powder sales by frontline health workers on the prevalence of anaemia were used. Multivariate logistic regression was used to identify risk factors for anaemia and ID, and population attributable fractions (PAF) were computed to estimate the proportion of anaemia that might be prevented by the elimination of individual risk factors. It was found that 68 % of the infants were anaemic, 56 % were Fe deficient, and one-third had evidence of subclinical infections. The prevalence of anaemia and ID increased rapidly, until 8–9 months of age, while that of subclinical infections was constant. ID (adjusted OR (AOR) 2·6–5·0;P< 0·001) and subclinical infections (AOR 1·4–1·5;P< 0·01) were major risk factors for anaemia, in addition to age and male sex. Similarly, subclinical infections, age and male sex were significant risk factors for ID. Previous-day consumption of Fe-rich foods was very low and not associated with anaemia or ID. The PAF of anaemia attributable to ID was 67 % (95 % CI 62, 71) and that of subclinical infections was 16 % (95 % CI 11, 20). These results suggest that a multipronged strategy that combines improvements in dietary Fe intake alongside infection control strategies is needed to prevent anaemia during infancy in Bangladesh.
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spelling CGSpace1510322024-10-25T07:58:12Z Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices Rawat, Rahul Saha, Kuntal K. Kennedy, Andrew Rohner, Fabian Ruel, Marie T. Menon, Purnima infection anaemia infants deficiency diseases best practices iron feeding habits Few data exist on the aetiology of anaemia and Fe deficiency (ID) during early infancy in South Asia. The present study aimed to determine the contribution of ID, infections and feeding practices to anaemia in Bangladeshi infants aged 6–11 months. Baseline data from 1600 infants recruited into a cluster-randomised trial testing the effectiveness of micronutrient powder sales by frontline health workers on the prevalence of anaemia were used. Multivariate logistic regression was used to identify risk factors for anaemia and ID, and population attributable fractions (PAF) were computed to estimate the proportion of anaemia that might be prevented by the elimination of individual risk factors. It was found that 68 % of the infants were anaemic, 56 % were Fe deficient, and one-third had evidence of subclinical infections. The prevalence of anaemia and ID increased rapidly, until 8–9 months of age, while that of subclinical infections was constant. ID (adjusted OR (AOR) 2·6–5·0;P< 0·001) and subclinical infections (AOR 1·4–1·5;P< 0·01) were major risk factors for anaemia, in addition to age and male sex. Similarly, subclinical infections, age and male sex were significant risk factors for ID. Previous-day consumption of Fe-rich foods was very low and not associated with anaemia or ID. The PAF of anaemia attributable to ID was 67 % (95 % CI 62, 71) and that of subclinical infections was 16 % (95 % CI 11, 20). These results suggest that a multipronged strategy that combines improvements in dietary Fe intake alongside infection control strategies is needed to prevent anaemia during infancy in Bangladesh. 2014 2024-08-01T02:54:55Z 2024-08-01T02:54:55Z Journal Article https://hdl.handle.net/10568/151032 en Limited Access Cambridge University Press Rawat, Rahul; Saha, Kuntal K.; Kennedy, Andrew; Rohner, Fabian; Ruel, Marie T.; and Menon, Purnima. Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices. British Journal of Nutrition 111(1): 172-181. https://doi.org/10.1017/s0007114513001852
spellingShingle infection
anaemia
infants
deficiency diseases
best practices
iron
feeding habits
Rawat, Rahul
Saha, Kuntal K.
Kennedy, Andrew
Rohner, Fabian
Ruel, Marie T.
Menon, Purnima
Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title_full Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title_fullStr Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title_full_unstemmed Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title_short Anaemia in infancy in rural Bangladesh: Contribution of iron deficiency, infections and poor feeding practices
title_sort anaemia in infancy in rural bangladesh contribution of iron deficiency infections and poor feeding practices
topic infection
anaemia
infants
deficiency diseases
best practices
iron
feeding habits
url https://hdl.handle.net/10568/151032
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