Multi-causal determinants of anemia among women of reproductive age in Vietnam

We examined the determinants of anemia using data obtained at baseline from 4986 women of reproductive age participating in a micronutrient supplementation trial in rural, North Vietnam. Hemoglobin (Hb) was measured from capillary blood samples using Hemocue. Plasma ferritin and retinol binding prot...

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Main Authors: Nguyen, Phuong Hong, Gonzalez-Casanova, Ines, Nguyen, Hieu, Pham, Hoa, Truong, Truong, Nguyen, Son, Martorell, Reynaldo, Ramakrishnan, Usha
Format: Abstract
Language:Inglés
Published: Wiley 2014
Subjects:
Online Access:https://hdl.handle.net/10568/149899
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author Nguyen, Phuong Hong
Gonzalez-Casanova, Ines
Nguyen, Hieu
Pham, Hoa
Truong, Truong
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
author_browse Gonzalez-Casanova, Ines
Martorell, Reynaldo
Nguyen, Hieu
Nguyen, Phuong Hong
Nguyen, Son
Pham, Hoa
Ramakrishnan, Usha
Truong, Truong
author_facet Nguyen, Phuong Hong
Gonzalez-Casanova, Ines
Nguyen, Hieu
Pham, Hoa
Truong, Truong
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
author_sort Nguyen, Phuong Hong
collection Repository of Agricultural Research Outputs (CGSpace)
description We examined the determinants of anemia using data obtained at baseline from 4986 women of reproductive age participating in a micronutrient supplementation trial in rural, North Vietnam. Hemoglobin (Hb) was measured from capillary blood samples using Hemocue. Plasma ferritin and retinol binding protein (RBP) were measured using the ELISA method. The prevalence of anemia (Hb<12 g/l), iron deficiency (Fe<12 µg/L), insufficient iron stores (Fe<30 µg/L) and iron deficiency anemia were 19.7%, 3.5%, 14.4% and 1.9%, respectively. The results using Structural Equation Modeling (SEM) techniques showed that ferritin concentration (0.29 per log‐mg/dl), number of children (‐0.19), and socioeconomic status (0.09) were directly associated with Hb concentration (p<0.05 for all). RBP was associated with Hb both directly (0.28 mg/dl) and indirectly (0.09 mg/dl) through ferritin (p<0.001), and hookworm infection was indirectly associated with Hb (‐0.11) through RBP and ferritin (p=0.025). Meat consumption, occupation, education, owning a hygienic toilet, and food insecurity however were not associated with Hb. Contrary to expectations, iron deficiency accounted for a very small proportion of anemia. These findings demonstrate the complex etiology of anemia and provide a useful framework that could be used to target and evaluate appropriate strategies for the prevention of anemia in similar settings and other populations.Supported by the Micronutrient Initiative and the Mathile Institute for the Advancement of Human Nutrition
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spelling CGSpace1498992025-04-03T21:29:13Z Multi-causal determinants of anemia among women of reproductive age in Vietnam Nguyen, Phuong Hong Gonzalez-Casanova, Ines Nguyen, Hieu Pham, Hoa Truong, Truong Nguyen, Son Martorell, Reynaldo Ramakrishnan, Usha reproductive stage anaemia gender trace elements women We examined the determinants of anemia using data obtained at baseline from 4986 women of reproductive age participating in a micronutrient supplementation trial in rural, North Vietnam. Hemoglobin (Hb) was measured from capillary blood samples using Hemocue. Plasma ferritin and retinol binding protein (RBP) were measured using the ELISA method. The prevalence of anemia (Hb<12 g/l), iron deficiency (Fe<12 µg/L), insufficient iron stores (Fe<30 µg/L) and iron deficiency anemia were 19.7%, 3.5%, 14.4% and 1.9%, respectively. The results using Structural Equation Modeling (SEM) techniques showed that ferritin concentration (0.29 per log‐mg/dl), number of children (‐0.19), and socioeconomic status (0.09) were directly associated with Hb concentration (p<0.05 for all). RBP was associated with Hb both directly (0.28 mg/dl) and indirectly (0.09 mg/dl) through ferritin (p<0.001), and hookworm infection was indirectly associated with Hb (‐0.11) through RBP and ferritin (p=0.025). Meat consumption, occupation, education, owning a hygienic toilet, and food insecurity however were not associated with Hb. Contrary to expectations, iron deficiency accounted for a very small proportion of anemia. These findings demonstrate the complex etiology of anemia and provide a useful framework that could be used to target and evaluate appropriate strategies for the prevention of anemia in similar settings and other populations.Supported by the Micronutrient Initiative and the Mathile Institute for the Advancement of Human Nutrition 2014 2024-08-01T02:50:11Z 2024-08-01T02:50:11Z Abstract https://hdl.handle.net/10568/149899 en Limited Access Wiley Nguyen, Phuong Hong; Gonzalez-Casanova, Ines; Nguyen, Hieu; Pham, Hoa; Truong, Truong; Nguyen, Son; Martorell, Reynaldo; and Usha Ramakrishnan. 2014. Multi-causal determinants of anemia among women of reproductive age in Vietnam. FASEB Journal 28(1 Supplement): 804.7. https://doi.org/10.1096/fasebj.28.1_supplement.804.7
spellingShingle reproductive stage
anaemia
gender
trace elements
women
Nguyen, Phuong Hong
Gonzalez-Casanova, Ines
Nguyen, Hieu
Pham, Hoa
Truong, Truong
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
Multi-causal determinants of anemia among women of reproductive age in Vietnam
title Multi-causal determinants of anemia among women of reproductive age in Vietnam
title_full Multi-causal determinants of anemia among women of reproductive age in Vietnam
title_fullStr Multi-causal determinants of anemia among women of reproductive age in Vietnam
title_full_unstemmed Multi-causal determinants of anemia among women of reproductive age in Vietnam
title_short Multi-causal determinants of anemia among women of reproductive age in Vietnam
title_sort multi causal determinants of anemia among women of reproductive age in vietnam
topic reproductive stage
anaemia
gender
trace elements
women
url https://hdl.handle.net/10568/149899
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