Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi

Reducing the inappropriate use of antibiotics in food animals is a global priority to address antimicrobial resistance (AMR). We investigated practices and factors associated with antibiotic use in small-scale commercial broiler farms in Lilongwe district, Malawi. We used structured questionnaires t...

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Autores principales: Ngunguni, S.M., Moodley, Arshnee, Msefula, C., Mkakosya, R., Muloi, Dishon M.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2024
Materias:
Acceso en línea:https://hdl.handle.net/10568/148868
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author Ngunguni, S.M.
Moodley, Arshnee
Msefula, C.
Mkakosya, R.
Muloi, Dishon M.
author_browse Mkakosya, R.
Moodley, Arshnee
Msefula, C.
Muloi, Dishon M.
Ngunguni, S.M.
author_facet Ngunguni, S.M.
Moodley, Arshnee
Msefula, C.
Mkakosya, R.
Muloi, Dishon M.
author_sort Ngunguni, S.M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Reducing the inappropriate use of antibiotics in food animals is a global priority to address antimicrobial resistance (AMR). We investigated practices and factors associated with antibiotic use in small-scale commercial broiler farms in Lilongwe district, Malawi. We used structured questionnaires to collect data on recent antibiotic use practices among 128 broiler farmers, who kept between 50 and 1 000 birds, from December 2022 to March 2023. Logistic regression analysis was used to identify risk factors associated with antibiotic use. Over half (53.1 %, n=68) of the farms reported using antibiotics at least once in the previous production cycle. Overall, 11 different types of antibiotics were used either for treatment and/or preventive purposes, with oxytetracycline (88.2 %), erythromycin (29.4 %), and enrofloxacin (26.5 %) reported as the frequently used. One-third of all antibiotic formulations contained multiple active antibiotic ingredients, with 12 % containing four antibiotics. Covariates associated with an increased likelihood of antibiotic use include disease incidence (OR=13.8, 95 % CI 5.27–42.50, p<0.001) and entry of wild birds into poultry houses (OR=3.56, 95 % CI =1.44–9.61, p=0.008). Our study highlights inappropriate usage of antibiotics, largely associated with reduced biosecurity and disease incidence. These findings underscore the need to strengthen veterinary services, reinforce regulations on antibiotic access and use, and farmer education programs promoting proper husbandry, biosecurity, and responsible antibiotic use.
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spelling CGSpace1488682025-10-26T12:52:17Z Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi Ngunguni, S.M. Moodley, Arshnee Msefula, C. Mkakosya, R. Muloi, Dishon M. antimicrobial resistance poultry Reducing the inappropriate use of antibiotics in food animals is a global priority to address antimicrobial resistance (AMR). We investigated practices and factors associated with antibiotic use in small-scale commercial broiler farms in Lilongwe district, Malawi. We used structured questionnaires to collect data on recent antibiotic use practices among 128 broiler farmers, who kept between 50 and 1 000 birds, from December 2022 to March 2023. Logistic regression analysis was used to identify risk factors associated with antibiotic use. Over half (53.1 %, n=68) of the farms reported using antibiotics at least once in the previous production cycle. Overall, 11 different types of antibiotics were used either for treatment and/or preventive purposes, with oxytetracycline (88.2 %), erythromycin (29.4 %), and enrofloxacin (26.5 %) reported as the frequently used. One-third of all antibiotic formulations contained multiple active antibiotic ingredients, with 12 % containing four antibiotics. Covariates associated with an increased likelihood of antibiotic use include disease incidence (OR=13.8, 95 % CI 5.27–42.50, p<0.001) and entry of wild birds into poultry houses (OR=3.56, 95 % CI =1.44–9.61, p=0.008). Our study highlights inappropriate usage of antibiotics, largely associated with reduced biosecurity and disease incidence. These findings underscore the need to strengthen veterinary services, reinforce regulations on antibiotic access and use, and farmer education programs promoting proper husbandry, biosecurity, and responsible antibiotic use. 2024-09 2024-07-03T12:52:05Z 2024-07-03T12:52:05Z Journal Article https://hdl.handle.net/10568/148868 en Open Access Elsevier Ngunguni, S.M., Moodley, A., Msefula, C., Mkakosya, R. and Muloi, D.M. 2024. Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi. Preventive Veterinary Medicine 230: 106263.
spellingShingle antimicrobial resistance
poultry
Ngunguni, S.M.
Moodley, Arshnee
Msefula, C.
Mkakosya, R.
Muloi, Dishon M.
Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title_full Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title_fullStr Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title_full_unstemmed Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title_short Patterns and drivers of antibiotic use in small-scale broiler production systems in Lilongwe District, Malawi
title_sort patterns and drivers of antibiotic use in small scale broiler production systems in lilongwe district malawi
topic antimicrobial resistance
poultry
url https://hdl.handle.net/10568/148868
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AT msefulac patternsanddriversofantibioticuseinsmallscalebroilerproductionsystemsinlilongwedistrictmalawi
AT mkakosyar patternsanddriversofantibioticuseinsmallscalebroilerproductionsystemsinlilongwedistrictmalawi
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