The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali

Background Evidence suggests that both preventive and curative nutrition interventions are needed to tackle child acute malnutrition (AM) in developing countries. In addition to reducing the incidence of AM, providing preventive interventions may also help increase attendance (and coverage) of AM sc...

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Autores principales: Huybregts, Lieven, Becquey, Elodie, Zongrone, Amanda, Le Port, Agnès, Khassanova, Regina, Coulibaly, Lazare, Leroy, Jef L., Rawat, Rahul, Ruel, Marie T.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2017
Materias:
Acceso en línea:https://hdl.handle.net/10568/148449
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author Huybregts, Lieven
Becquey, Elodie
Zongrone, Amanda
Le Port, Agnès
Khassanova, Regina
Coulibaly, Lazare
Leroy, Jef L.
Rawat, Rahul
Ruel, Marie T.
author_browse Becquey, Elodie
Coulibaly, Lazare
Huybregts, Lieven
Khassanova, Regina
Le Port, Agnès
Leroy, Jef L.
Rawat, Rahul
Ruel, Marie T.
Zongrone, Amanda
author_facet Huybregts, Lieven
Becquey, Elodie
Zongrone, Amanda
Le Port, Agnès
Khassanova, Regina
Coulibaly, Lazare
Leroy, Jef L.
Rawat, Rahul
Ruel, Marie T.
author_sort Huybregts, Lieven
collection Repository of Agricultural Research Outputs (CGSpace)
description Background Evidence suggests that both preventive and curative nutrition interventions are needed to tackle child acute malnutrition (AM) in developing countries. In addition to reducing the incidence of AM, providing preventive interventions may also help increase attendance (and coverage) of AM screening, a major constraint in the community-based management of child acute malnutrition (CMAM) model. There is a paucity of evidence-based strategies to deliver integrated preventive and curative interventions effectively and affordably at scale. The aim of the Innovative Approaches for the Prevention of Childhood Malnutrition (PROMIS) study is to assess the feasibility, quality of implementation, effectiveness and cost-effectiveness of an integrated child malnutrition prevention and treatment intervention package implemented through a community-based platform in Mali and a facility-based platform in Burkina Faso. Methods/Design The PROMIS intervention entails a comprehensive preventive package offered on a monthly basis to caregivers of children, while children are screened for acute malnutrition (AM). The package consists of behavior change communication on essential nutrition and hygiene actions, and monthly preventive doses of small quantity lipid-based nutrient supplements (SQ-LNS) for children aged 6 to 23.9 months. Positive AM cases are referred to treatment services offered by first-line health services according to the CMAM model. The PROMIS intervention will be evaluated using a mixed methods approach. The impact study encompasses two types of study design: i) repeated cross-sectional surveys conducted at baseline and at endline after 24 months of program implementation and ii) a longitudinal study with a monthly follow-up for 18 months. Primary study impact measures include the incidence and endpoint prevalence of AM, AM screening coverage and treatment compliance. A process evaluation will assess the feasibility and quality of implementation of the intervention guided by country specific program impact pathways (PIPs). Cost-effectiveness analysis will assess the economic feasibility of the intervention. Discussion The PROMIS study assesses the effectiveness of an innovative model to integrate prevention and treatment interventions for greater and more sustainable impacts on the incidence and prevalence of AM using a rigorous, theory-based randomized control trial approach. This type of programmatic research is urgently needed to help program implementers, policy makers, and investors prioritize, select and scale-up the best program models to prevent and treat AM and achieve the World Health Assembly goal of reducing childhood wasting to less than 5% globally by the year 2025.
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spelling CGSpace1484492025-12-08T10:29:22Z The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali Huybregts, Lieven Becquey, Elodie Zongrone, Amanda Le Port, Agnès Khassanova, Regina Coulibaly, Lazare Leroy, Jef L. Rawat, Rahul Ruel, Marie T. lipids economic analysis child nutrition nutritional disorders capacity development nutrients malnutrition supplements children developing countries wasting disease (nutritional disorder) behaviour diet cost analysis Background Evidence suggests that both preventive and curative nutrition interventions are needed to tackle child acute malnutrition (AM) in developing countries. In addition to reducing the incidence of AM, providing preventive interventions may also help increase attendance (and coverage) of AM screening, a major constraint in the community-based management of child acute malnutrition (CMAM) model. There is a paucity of evidence-based strategies to deliver integrated preventive and curative interventions effectively and affordably at scale. The aim of the Innovative Approaches for the Prevention of Childhood Malnutrition (PROMIS) study is to assess the feasibility, quality of implementation, effectiveness and cost-effectiveness of an integrated child malnutrition prevention and treatment intervention package implemented through a community-based platform in Mali and a facility-based platform in Burkina Faso. Methods/Design The PROMIS intervention entails a comprehensive preventive package offered on a monthly basis to caregivers of children, while children are screened for acute malnutrition (AM). The package consists of behavior change communication on essential nutrition and hygiene actions, and monthly preventive doses of small quantity lipid-based nutrient supplements (SQ-LNS) for children aged 6 to 23.9 months. Positive AM cases are referred to treatment services offered by first-line health services according to the CMAM model. The PROMIS intervention will be evaluated using a mixed methods approach. The impact study encompasses two types of study design: i) repeated cross-sectional surveys conducted at baseline and at endline after 24 months of program implementation and ii) a longitudinal study with a monthly follow-up for 18 months. Primary study impact measures include the incidence and endpoint prevalence of AM, AM screening coverage and treatment compliance. A process evaluation will assess the feasibility and quality of implementation of the intervention guided by country specific program impact pathways (PIPs). Cost-effectiveness analysis will assess the economic feasibility of the intervention. Discussion The PROMIS study assesses the effectiveness of an innovative model to integrate prevention and treatment interventions for greater and more sustainable impacts on the incidence and prevalence of AM using a rigorous, theory-based randomized control trial approach. This type of programmatic research is urgently needed to help program implementers, policy makers, and investors prioritize, select and scale-up the best program models to prevent and treat AM and achieve the World Health Assembly goal of reducing childhood wasting to less than 5% globally by the year 2025. 2017 2024-06-21T09:24:43Z 2024-06-21T09:24:43Z Journal Article https://hdl.handle.net/10568/148449 en https://doi.org/10.1093/ajcn/nqab277 Open Access Springer Huybregts, Lieven; Becquey, Elodie; Zongrone, Amanda; Le Port, Agnès; Khassanova, Regina; Coulibaly, Lazare; Leroy, Jef L.; Rawat, Rahul; and Ruel, Marie T. 2017. The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali. BMC Public Health 17 (1): 237. https://doi.org/10.1186/s12889-017-4146-6
spellingShingle lipids
economic analysis
child nutrition
nutritional disorders
capacity development
nutrients
malnutrition
supplements
children
developing countries
wasting disease (nutritional disorder)
behaviour
diet
cost analysis
Huybregts, Lieven
Becquey, Elodie
Zongrone, Amanda
Le Port, Agnès
Khassanova, Regina
Coulibaly, Lazare
Leroy, Jef L.
Rawat, Rahul
Ruel, Marie T.
The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title_full The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title_fullStr The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title_full_unstemmed The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title_short The impact of integrated prevention and treatment on child malnutrition and health: The PROMIS project, a randomized control trial in Burkina Faso and Mali
title_sort impact of integrated prevention and treatment on child malnutrition and health the promis project a randomized control trial in burkina faso and mali
topic lipids
economic analysis
child nutrition
nutritional disorders
capacity development
nutrients
malnutrition
supplements
children
developing countries
wasting disease (nutritional disorder)
behaviour
diet
cost analysis
url https://hdl.handle.net/10568/148449
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