Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam

Small for gestational age (SGA) is a global health problem. Identifying the timing of fetal growth faltering is critical for developing preventive interventions. We aim to describe patterns of fetal growth and to predict SGA at birth using fetal ultrasound measurements.We studied 1412 pregnant women...

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Autores principales: Nguyen, Phuong Hong, Addo, O. Yaw, Young, Melissa, Gonzalez-Casanova, Ines, Pham, Hoa, Truong, Truong V., Nguyen, Son, Martorell, Reynaldo, Ramakrishnan, Usha
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2016
Materias:
Acceso en línea:https://hdl.handle.net/10568/148102
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author Nguyen, Phuong Hong
Addo, O. Yaw
Young, Melissa
Gonzalez-Casanova, Ines
Pham, Hoa
Truong, Truong V.
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
author_browse Addo, O. Yaw
Gonzalez-Casanova, Ines
Martorell, Reynaldo
Nguyen, Phuong Hong
Nguyen, Son
Pham, Hoa
Ramakrishnan, Usha
Truong, Truong V.
Young, Melissa
author_facet Nguyen, Phuong Hong
Addo, O. Yaw
Young, Melissa
Gonzalez-Casanova, Ines
Pham, Hoa
Truong, Truong V.
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
author_sort Nguyen, Phuong Hong
collection Repository of Agricultural Research Outputs (CGSpace)
description Small for gestational age (SGA) is a global health problem. Identifying the timing of fetal growth faltering is critical for developing preventive interventions. We aim to describe patterns of fetal growth and to predict SGA at birth using fetal ultrasound measurements.We studied 1412 pregnant women enrolled in a randomised‐controlled trial evaluating maternal micronutrient supplementation in Thai Nguyen province, Vietnam. Ultrasound examinations included biparietal diameter (BPD), head circumference (HC) and abdominal circumference (AC), and femur length (FL). Measures were assessed using the new international fetal growth standards (INTERGROWTH‐21st Project). Generalised linear mixed logit regression models were used to examine the association between ultrasound measures and SGA at birth.Overall fetal growth restriction began in early pregnancy and continued through delivery, but the timing of growth faltering varied by measure: it began by 20 weeks for HC, BPD and AC, earlier as compared to FL growth that started >30 weeks. SGA infants had significantly lower mean fetal growth parameters as early as 14 weeks. Ultrasound measures below the 10th percentile were associated with a two to four times higher risk of SGA at birth compared to fetuses greater than the 50th percentile, with the largest odds ratios for AC (OR 3.9, 95% confidence interval (CI) 2.7, 5.7).Fetal growth faltering by ultrasound begins in early gestation among rural Vietnamese populations; these patterns clearly identified those to be born SGA. Efforts to prevent fetal growth faltering must begin early in pregnancy and perhaps even before pregnancy.
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spelling CGSpace1481022025-04-03T21:29:14Z Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam Nguyen, Phuong Hong Addo, O. Yaw Young, Melissa Gonzalez-Casanova, Ines Pham, Hoa Truong, Truong V. Nguyen, Son Martorell, Reynaldo Ramakrishnan, Usha maternal and child health stunting ultrasound Small for gestational age (SGA) is a global health problem. Identifying the timing of fetal growth faltering is critical for developing preventive interventions. We aim to describe patterns of fetal growth and to predict SGA at birth using fetal ultrasound measurements.We studied 1412 pregnant women enrolled in a randomised‐controlled trial evaluating maternal micronutrient supplementation in Thai Nguyen province, Vietnam. Ultrasound examinations included biparietal diameter (BPD), head circumference (HC) and abdominal circumference (AC), and femur length (FL). Measures were assessed using the new international fetal growth standards (INTERGROWTH‐21st Project). Generalised linear mixed logit regression models were used to examine the association between ultrasound measures and SGA at birth.Overall fetal growth restriction began in early pregnancy and continued through delivery, but the timing of growth faltering varied by measure: it began by 20 weeks for HC, BPD and AC, earlier as compared to FL growth that started >30 weeks. SGA infants had significantly lower mean fetal growth parameters as early as 14 weeks. Ultrasound measures below the 10th percentile were associated with a two to four times higher risk of SGA at birth compared to fetuses greater than the 50th percentile, with the largest odds ratios for AC (OR 3.9, 95% confidence interval (CI) 2.7, 5.7).Fetal growth faltering by ultrasound begins in early gestation among rural Vietnamese populations; these patterns clearly identified those to be born SGA. Efforts to prevent fetal growth faltering must begin early in pregnancy and perhaps even before pregnancy. 2016-02-18 2024-06-21T09:23:50Z 2024-06-21T09:23:50Z Journal Article https://hdl.handle.net/10568/148102 en Wiley Nguyen, Phuong Hong; Addo, O. Yaw; Young, Melissa; Gonzalez-Casanova, Ines; Pham, Hoa; Truong, Truong V.; Nguyen, Son; Martorell, Reynaldo; and Ramakrishnan, Usha. 2016. Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam. Paediatric and Perinatal Epidemiology 30(3): 256 - 266. https://doi.org/10.1111/ppe.12276
spellingShingle maternal and child health
stunting
ultrasound
Nguyen, Phuong Hong
Addo, O. Yaw
Young, Melissa
Gonzalez-Casanova, Ines
Pham, Hoa
Truong, Truong V.
Nguyen, Son
Martorell, Reynaldo
Ramakrishnan, Usha
Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title_full Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title_fullStr Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title_full_unstemmed Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title_short Patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural Vietnam
title_sort patterns of fetal growth based on ultrasound measurement and its relationship with small for gestational age at birth in rural vietnam
topic maternal and child health
stunting
ultrasound
url https://hdl.handle.net/10568/148102
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