Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo
Little is known about the micronutrient status of women and children in the Democratic Republic of the Congo, which is critical for the design of effective nutrition interventions. We recruited 744 mother-child pairs from South Kivu (SK) and Kongo Central (KC). We determined hemoglobin (Hb), serum z...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
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MDPI
2016
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/146342 |
| _version_ | 1855527864877711360 |
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| author | Harvey-Leeson, Sarah Karakochuk, Crystal D. Hawes, Meaghan Tugirimana, Pierrot L. Bahizire, Esto Akilimali, Pierre Z. Michaux, Kristina D. Lynd, Larry D. Whitfield, Kyly C. Moursi, Mourad Boy, Erick Foley, Jennifer McLean, Judy Houghton, Lisa A. Gibson, Rosalind S. Green, Tim J. |
| author_browse | Akilimali, Pierre Z. Bahizire, Esto Boy, Erick Foley, Jennifer Gibson, Rosalind S. Green, Tim J. Harvey-Leeson, Sarah Hawes, Meaghan Houghton, Lisa A. Karakochuk, Crystal D. Lynd, Larry D. McLean, Judy Michaux, Kristina D. Moursi, Mourad Tugirimana, Pierrot L. Whitfield, Kyly C. |
| author_facet | Harvey-Leeson, Sarah Karakochuk, Crystal D. Hawes, Meaghan Tugirimana, Pierrot L. Bahizire, Esto Akilimali, Pierre Z. Michaux, Kristina D. Lynd, Larry D. Whitfield, Kyly C. Moursi, Mourad Boy, Erick Foley, Jennifer McLean, Judy Houghton, Lisa A. Gibson, Rosalind S. Green, Tim J. |
| author_sort | Harvey-Leeson, Sarah |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Little is known about the micronutrient status of women and children in the Democratic Republic of the Congo, which is critical for the design of effective nutrition interventions. We recruited 744 mother-child pairs from South Kivu (SK) and Kongo Central (KC). We determined hemoglobin (Hb), serum zinc, vitamin B12, folate, ferritin, soluble transferrin receptor (sTfR), retinol binding protein (RBP), C-reactive protein, and α-1 acid glycoprotein concentrations. Anemia prevalence was determined using Hb adjusted for altitude alone and Hb adjusted for both altitude and ethnicity. Anemia prevalence was lower after Hb adjustment for altitude and ethnicity, compared to only altitude, among women (6% vs. 17% in SK; 10% vs. 32% in KC), children 6–23 months (26% vs. 59% in SK; 25% vs. 42% in KC), and children 24–59 months (14% vs. 35% in SK; 23% vs. 44% in KC), respectively. Iron deficiency was seemingly higher with sTfR as compared to inflammation-adjusted ferritin among women (18% vs. 4% in SK; 21% vs. 5% in KC), children 6–23 months (51% vs. 14% in SK; 74% vs. 10% in KC), and children 24–59 months (23% vs. 4% in SK; 58% vs. 1% in KC). Regardless of indicator, iron deficiency anemia (IDA) never exceeded 3% in women. In children, IDA reached almost 20% when sTfR was used but was only 10% with ferritin. Folate, B12, and vitamin A (RBP) deficiencies were all very low (<5%); RBP was 10% in children. The prevalence of anemia was unexpectedly low. Inflammation-adjusted zinc deficiency was high among women (52% in SK; 58% in KC), children 6–23 months (23% in SK; 20% in KC), and children 24–59 months (25% in SK; 27% in KC). The rate of biochemical zinc deficiency among Congolese women and children requires attention. |
| format | Journal Article |
| id | CGSpace146342 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1463422025-12-08T10:29:22Z Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo Harvey-Leeson, Sarah Karakochuk, Crystal D. Hawes, Meaghan Tugirimana, Pierrot L. Bahizire, Esto Akilimali, Pierre Z. Michaux, Kristina D. Lynd, Larry D. Whitfield, Kyly C. Moursi, Mourad Boy, Erick Foley, Jennifer McLean, Judy Houghton, Lisa A. Gibson, Rosalind S. Green, Tim J. ferritin anaemia deficiency diseases gender haemoglobin trace elements inflammation iron deficiency women Little is known about the micronutrient status of women and children in the Democratic Republic of the Congo, which is critical for the design of effective nutrition interventions. We recruited 744 mother-child pairs from South Kivu (SK) and Kongo Central (KC). We determined hemoglobin (Hb), serum zinc, vitamin B12, folate, ferritin, soluble transferrin receptor (sTfR), retinol binding protein (RBP), C-reactive protein, and α-1 acid glycoprotein concentrations. Anemia prevalence was determined using Hb adjusted for altitude alone and Hb adjusted for both altitude and ethnicity. Anemia prevalence was lower after Hb adjustment for altitude and ethnicity, compared to only altitude, among women (6% vs. 17% in SK; 10% vs. 32% in KC), children 6–23 months (26% vs. 59% in SK; 25% vs. 42% in KC), and children 24–59 months (14% vs. 35% in SK; 23% vs. 44% in KC), respectively. Iron deficiency was seemingly higher with sTfR as compared to inflammation-adjusted ferritin among women (18% vs. 4% in SK; 21% vs. 5% in KC), children 6–23 months (51% vs. 14% in SK; 74% vs. 10% in KC), and children 24–59 months (23% vs. 4% in SK; 58% vs. 1% in KC). Regardless of indicator, iron deficiency anemia (IDA) never exceeded 3% in women. In children, IDA reached almost 20% when sTfR was used but was only 10% with ferritin. Folate, B12, and vitamin A (RBP) deficiencies were all very low (<5%); RBP was 10% in children. The prevalence of anemia was unexpectedly low. Inflammation-adjusted zinc deficiency was high among women (52% in SK; 58% in KC), children 6–23 months (23% in SK; 20% in KC), and children 24–59 months (25% in SK; 27% in KC). The rate of biochemical zinc deficiency among Congolese women and children requires attention. 2016-02-25 2024-06-21T09:06:42Z 2024-06-21T09:06:42Z Journal Article https://hdl.handle.net/10568/146342 en Open Access MDPI Harvey-Leeson, Sarah; Karakochuk, Crystal D.; Hawes, Meaghan; Tugirimana, Pierrot L.; Bahizire, Esto; Akilimali, Pierre Z.; Michaux, Kristina D.; Lynd, Larry D.; Whitfield, Kyly C.; Moursi, Mourad; Boy, Erick; Foley, Jennifer; McLean, Judy; Houghton, Lisa A.; Gibson, Rosalind S.; and Green, Tim J. 2016. Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo. Nutrients 8(2): 98. https://doi.org/10.3390/nu8020098 |
| spellingShingle | ferritin anaemia deficiency diseases gender haemoglobin trace elements inflammation iron deficiency women Harvey-Leeson, Sarah Karakochuk, Crystal D. Hawes, Meaghan Tugirimana, Pierrot L. Bahizire, Esto Akilimali, Pierre Z. Michaux, Kristina D. Lynd, Larry D. Whitfield, Kyly C. Moursi, Mourad Boy, Erick Foley, Jennifer McLean, Judy Houghton, Lisa A. Gibson, Rosalind S. Green, Tim J. Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title | Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title_full | Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title_fullStr | Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title_full_unstemmed | Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title_short | Anemia and micronutrient status of women of childbearing age and children 6–59 months in the Democratic Republic of the Congo |
| title_sort | anemia and micronutrient status of women of childbearing age and children 6 59 months in the democratic republic of the congo |
| topic | ferritin anaemia deficiency diseases gender haemoglobin trace elements inflammation iron deficiency women |
| url | https://hdl.handle.net/10568/146342 |
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