Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants
The objective of this study was to assess plasma fatty acid (FA) patterns of 6‐month‐old South African infants and to determine their association with feeding practices, growth, and psychomotor development. Plasma total phospholipid FA composition (% of total FAs) of 6‐month‐old infants (n = 353) fr...
| Autores principales: | , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
John Wiley & Sons
2019
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/146199 |
| _version_ | 1855517800762703872 |
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| author | Siziba, Linda P. Baumgartner, Jeannine Ricci, Cristian Jacobs, Adriaan Rothman, Marinel Covic, Namukolo |
| author_browse | Baumgartner, Jeannine Covic, Namukolo Jacobs, Adriaan Ricci, Cristian Rothman, Marinel Siziba, Linda P. |
| author_facet | Siziba, Linda P. Baumgartner, Jeannine Ricci, Cristian Jacobs, Adriaan Rothman, Marinel Covic, Namukolo |
| author_sort | Siziba, Linda P. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The objective of this study was to assess plasma fatty acid (FA) patterns of 6‐month‐old South African infants and to determine their association with feeding practices, growth, and psychomotor development. Plasma total phospholipid FA composition (% of total FAs) of 6‐month‐old infants (n = 353) from a peri‐urban township was analysed, and principal component and factor analysis were performed to identify plasma FA patterns. Feeding practices, anthropometric measurements, and psychomotor development scores were determined. Four major plasma phospholipid FA patterns were identified: A plant‐based C18 FA , a high n‐6 long‐chain polyunsaturated fatty acids (LCPUFA) , a C16:1 and long‐chain saturated fatty acid (SFA) , and a high n‐3 and low n‐6 LCPUFA pattern. Formula feeding was associated with higher, whereas breastfeeding was associated with lower scores for the plant‐based C18 FA and C16:1 and long‐chain SFA patterns. On the other hand, breastfeeding, the consumption of cow's milk, and the consumption of semisolid foods were associated with higher scores, whereas formula feeding was associated with lower scores for the high n‐6 LCPUFA pattern. Breastfeeding and the consumption of semisolids were also associated with higher high n‐3 and low n‐6 LCPUFA pattern scores. The C16:1 and long‐chain SFA and high n‐3 and low n‐6 LCPUFA patterns were positively associated with psychomotor development scores. In 6‐month‐old South African infants, we identified distinct plasma FA patterns that presumably represent the FA quality of their diet and that are associated with psychomotor development. Our results suggest that breast milk is an important source of n‐6 LCPUFAs and formula‐fed infants may be at risk of inadequate LCPUFA intake. |
| format | Journal Article |
| id | CGSpace146199 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | John Wiley & Sons |
| publisherStr | John Wiley & Sons |
| record_format | dspace |
| spelling | CGSpace1461992024-10-25T07:54:14Z Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants Siziba, Linda P. Baumgartner, Jeannine Ricci, Cristian Jacobs, Adriaan Rothman, Marinel Covic, Namukolo fatty acids human milk infant feeding The objective of this study was to assess plasma fatty acid (FA) patterns of 6‐month‐old South African infants and to determine their association with feeding practices, growth, and psychomotor development. Plasma total phospholipid FA composition (% of total FAs) of 6‐month‐old infants (n = 353) from a peri‐urban township was analysed, and principal component and factor analysis were performed to identify plasma FA patterns. Feeding practices, anthropometric measurements, and psychomotor development scores were determined. Four major plasma phospholipid FA patterns were identified: A plant‐based C18 FA , a high n‐6 long‐chain polyunsaturated fatty acids (LCPUFA) , a C16:1 and long‐chain saturated fatty acid (SFA) , and a high n‐3 and low n‐6 LCPUFA pattern. Formula feeding was associated with higher, whereas breastfeeding was associated with lower scores for the plant‐based C18 FA and C16:1 and long‐chain SFA patterns. On the other hand, breastfeeding, the consumption of cow's milk, and the consumption of semisolid foods were associated with higher scores, whereas formula feeding was associated with lower scores for the high n‐6 LCPUFA pattern. Breastfeeding and the consumption of semisolids were also associated with higher high n‐3 and low n‐6 LCPUFA pattern scores. The C16:1 and long‐chain SFA and high n‐3 and low n‐6 LCPUFA patterns were positively associated with psychomotor development scores. In 6‐month‐old South African infants, we identified distinct plasma FA patterns that presumably represent the FA quality of their diet and that are associated with psychomotor development. Our results suggest that breast milk is an important source of n‐6 LCPUFAs and formula‐fed infants may be at risk of inadequate LCPUFA intake. 2019-07 2024-06-21T09:06:09Z 2024-06-21T09:06:09Z Journal Article https://hdl.handle.net/10568/146199 en Open Access John Wiley & Sons Siziba, Linda P.; Baumgartner, Jeannine; Ricci, Cristian; Jacobs, Adriaan; Rothman, Marinel; Covic, Namukolo; et al. 2019. Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants. Maternal and Child Nutrition 15(3): e12763. https://doi.org/10.1111/mcn.12763 |
| spellingShingle | fatty acids human milk infant feeding Siziba, Linda P. Baumgartner, Jeannine Ricci, Cristian Jacobs, Adriaan Rothman, Marinel Covic, Namukolo Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title | Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title_full | Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title_fullStr | Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title_full_unstemmed | Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title_short | Associations of plasma total phospholipid fatty acid patterns with feeding practices, growth and psychomotor development in six‐month‐old South African infants |
| title_sort | associations of plasma total phospholipid fatty acid patterns with feeding practices growth and psychomotor development in six month old south african infants |
| topic | fatty acids human milk infant feeding |
| url | https://hdl.handle.net/10568/146199 |
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