Maternal and child nutrition in the Lives Saved Tool: Results of a recent update

Background: The Lives Saved Tool (LiST) is a mathematical modelling tool for estimating the survival, health, and nutritional impacts of scaling intervention coverage in low- and middle-income countries (LMICs). Various nutrition interventions are included in LiST and are regularly (and independentl...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Hannah, Piwoz, Ellen G., Ruel, Marie T., Brown, Kenneth H., Black, Robert E., Walker, Neff
Formato: Journal Article
Lenguaje:Inglés
Publicado: International Society of Global Health 2022
Materias:
Acceso en línea:https://hdl.handle.net/10568/141375
_version_ 1855516375193223168
author Tong, Hannah
Piwoz, Ellen G.
Ruel, Marie T.
Brown, Kenneth H.
Black, Robert E.
Walker, Neff
author_browse Black, Robert E.
Brown, Kenneth H.
Piwoz, Ellen G.
Ruel, Marie T.
Tong, Hannah
Walker, Neff
author_facet Tong, Hannah
Piwoz, Ellen G.
Ruel, Marie T.
Brown, Kenneth H.
Black, Robert E.
Walker, Neff
author_sort Tong, Hannah
collection Repository of Agricultural Research Outputs (CGSpace)
description Background: The Lives Saved Tool (LiST) is a mathematical modelling tool for estimating the survival, health, and nutritional impacts of scaling intervention coverage in low- and middle-income countries (LMICs). Various nutrition interventions are included in LiST and are regularly (and independently) reviewed and updated as new data emerge. This manuscript describes our latest in-depth review of nutrition evidence, focusing on intervention efficacy, appropriate population-affected fractions, and new interventions for potential inclusion in the LiST model. Methods: An external advisory group (EAG) was assembled to review evidence from systematic reviews on intervention-outcome (I-O) pairs for women and children under five years of age. GRADE quality was assigned to each pair based on a LiST-specific checklist to facilitate consistent decisions during the consideration. For existing interventions with new information, the EAG was asked to recommend whether to update the default efficacy values and population-affected fractions. For the new interventions, the EAG decided whether there was sufficient evidence of benefit, and in affirmative cases, information on the efficacy and affected fraction values that could be used. Decisions were based on expert group consensus. Results: Overall, the group reviewed 53 nutrition-related I-O pairs, including 25 existing and 28 new ones. Efficacy and population-affected fractions were updated for seven I-O pairs; three pairs were updated for efficacy estimates only, three were updated for population-affected fractions only; and nine new I-O pairs were added to the model, bringing the total of nutrition-related I-O pairs to 34. Included in the new I-O pairs were two new nutrition interventions added to LIST: zinc fortification and neonatal vitamin A supplementation. Conclusions: For modelling tools like LiST to be useful, it is crucial to update interventions, efficacy and population-affected fractions as new evidence becomes available. The present updates will enable LiST users to better estimate the potential health, nutrition, and survival benefits of investing in nutrition.
format Journal Article
id CGSpace141375
institution CGIAR Consortium
language Inglés
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher International Society of Global Health
publisherStr International Society of Global Health
record_format dspace
spelling CGSpace1413752025-10-26T13:01:39Z Maternal and child nutrition in the Lives Saved Tool: Results of a recent update Tong, Hannah Piwoz, Ellen G. Ruel, Marie T. Brown, Kenneth H. Black, Robert E. Walker, Neff maternal and child health models health modelling nutrition children maternal nutrition Background: The Lives Saved Tool (LiST) is a mathematical modelling tool for estimating the survival, health, and nutritional impacts of scaling intervention coverage in low- and middle-income countries (LMICs). Various nutrition interventions are included in LiST and are regularly (and independently) reviewed and updated as new data emerge. This manuscript describes our latest in-depth review of nutrition evidence, focusing on intervention efficacy, appropriate population-affected fractions, and new interventions for potential inclusion in the LiST model. Methods: An external advisory group (EAG) was assembled to review evidence from systematic reviews on intervention-outcome (I-O) pairs for women and children under five years of age. GRADE quality was assigned to each pair based on a LiST-specific checklist to facilitate consistent decisions during the consideration. For existing interventions with new information, the EAG was asked to recommend whether to update the default efficacy values and population-affected fractions. For the new interventions, the EAG decided whether there was sufficient evidence of benefit, and in affirmative cases, information on the efficacy and affected fraction values that could be used. Decisions were based on expert group consensus. Results: Overall, the group reviewed 53 nutrition-related I-O pairs, including 25 existing and 28 new ones. Efficacy and population-affected fractions were updated for seven I-O pairs; three pairs were updated for efficacy estimates only, three were updated for population-affected fractions only; and nine new I-O pairs were added to the model, bringing the total of nutrition-related I-O pairs to 34. Included in the new I-O pairs were two new nutrition interventions added to LIST: zinc fortification and neonatal vitamin A supplementation. Conclusions: For modelling tools like LiST to be useful, it is crucial to update interventions, efficacy and population-affected fractions as new evidence becomes available. The present updates will enable LiST users to better estimate the potential health, nutrition, and survival benefits of investing in nutrition. 2022-12-30 2024-04-12T13:37:47Z 2024-04-12T13:37:47Z Journal Article https://hdl.handle.net/10568/141375 en Open Access International Society of Global Health Tong, Hannah; Piwoz, Ellen G.; Ruel, Marie T.; Brown, Kenneth H.; Black, Robert E.; and Walker, Neff. 2022. Maternal and child nutrition in the Lives Saved Tool: Results of a recent update. Journal of Global Health 12: 08005. https://doi.org/10.7189/jogh.12.08005
spellingShingle maternal and child health
models
health
modelling
nutrition
children
maternal nutrition
Tong, Hannah
Piwoz, Ellen G.
Ruel, Marie T.
Brown, Kenneth H.
Black, Robert E.
Walker, Neff
Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title_full Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title_fullStr Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title_full_unstemmed Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title_short Maternal and child nutrition in the Lives Saved Tool: Results of a recent update
title_sort maternal and child nutrition in the lives saved tool results of a recent update
topic maternal and child health
models
health
modelling
nutrition
children
maternal nutrition
url https://hdl.handle.net/10568/141375
work_keys_str_mv AT tonghannah maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate
AT piwozelleng maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate
AT ruelmariet maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate
AT brownkennethh maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate
AT blackroberte maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate
AT walkerneff maternalandchildnutritioninthelivessavedtoolresultsofarecentupdate