Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels

Anaemia control programmes in India are hampered by a lack of representative evidence on anaemia prevalence, burden and associated factors for adolescents. The aim of this study was to: (1) describe the national and subnational prevalence, severity and burden of anaemia among Indian adolescents; (2)...

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Autores principales: Scott, Samuel P., Lahiri, Anwesha, Sethi, Vani, de Wagt, Arjan, Menon, Purnima, Yadav, Kapil, Varghese, Mini, Joe, William, Vir, Sheila C., Nguyen, Phuong Hong
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2022
Materias:
Acceso en línea:https://hdl.handle.net/10568/141318
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author Scott, Samuel P.
Lahiri, Anwesha
Sethi, Vani
de Wagt, Arjan
Menon, Purnima
Yadav, Kapil
Varghese, Mini
Joe, William
Vir, Sheila C.
Nguyen, Phuong Hong
author_browse Joe, William
Lahiri, Anwesha
Menon, Purnima
Nguyen, Phuong Hong
Scott, Samuel P.
Sethi, Vani
Varghese, Mini
Vir, Sheila C.
Yadav, Kapil
de Wagt, Arjan
author_facet Scott, Samuel P.
Lahiri, Anwesha
Sethi, Vani
de Wagt, Arjan
Menon, Purnima
Yadav, Kapil
Varghese, Mini
Joe, William
Vir, Sheila C.
Nguyen, Phuong Hong
author_sort Scott, Samuel P.
collection Repository of Agricultural Research Outputs (CGSpace)
description Anaemia control programmes in India are hampered by a lack of representative evidence on anaemia prevalence, burden and associated factors for adolescents. The aim of this study was to: (1) describe the national and subnational prevalence, severity and burden of anaemia among Indian adolescents; (2) examine factors associated with anaemia at national and regional levels. Data (n = 14,673 individuals aged 10–19 years) were from India's Comprehensive National Nutrition Survey (CNNS, 2016–2018). CNNS used a multistage, stratified, probability proportion to size cluster sampling design. Prevalence was estimated using globally comparable age- and sex-specific cutoffs, using survey weights for biomarker sample collection. Burden analysis used prevalence estimates and projected population from 2011 Census data. Multivariable logistic regression models were used to analyse factors (diet, micronutrient deficiencies, haemoglobinopathies, sociodemographic factors, environment) associated with anaemia. Anaemia was present in 40% of girls and 18% of boys, equivalent to 72 million adolescents in 2018, and varied by region (girls 29%–46%; boys 11%–28%) and state (girls 7%–62%; boys 4%–32%). Iron deficiency (ferritin < 15 μg/L) was the strongest predictor of anaemia (odds ratio [OR]: 4.68, 95% confidence interval [CI]: [3.21,6.83]), followed by haemoglobinopathies (HbA2 > 3.5% or any HbS) (OR: 2.81, 95% CI: [1.66,4.74]), vitamin A deficiency (serum retinol <20 ng/ml) (OR: 1.86, 95% CI: [1.23,2.80]) and zinc deficiency (serum zinc < 70 μg/L) (OR: 1.32, 95% CI: [1.02,1.72]). Regional models show heterogeneity in the strength of association between factors and anaemia by region. Adolescent anaemia control programmes in India should continue to address iron deficiency, strengthen strategies to identify haemoglobinopathies and other micronutrient deficiencies, and further explore geographic variation in associated factors.
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spelling CGSpace1413182025-10-28T10:12:08Z Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels Scott, Samuel P. Lahiri, Anwesha Sethi, Vani de Wagt, Arjan Menon, Purnima Yadav, Kapil Varghese, Mini Joe, William Vir, Sheila C. Nguyen, Phuong Hong anaemia adolescents trace element deficiencies trace elements public health Anaemia control programmes in India are hampered by a lack of representative evidence on anaemia prevalence, burden and associated factors for adolescents. The aim of this study was to: (1) describe the national and subnational prevalence, severity and burden of anaemia among Indian adolescents; (2) examine factors associated with anaemia at national and regional levels. Data (n = 14,673 individuals aged 10–19 years) were from India's Comprehensive National Nutrition Survey (CNNS, 2016–2018). CNNS used a multistage, stratified, probability proportion to size cluster sampling design. Prevalence was estimated using globally comparable age- and sex-specific cutoffs, using survey weights for biomarker sample collection. Burden analysis used prevalence estimates and projected population from 2011 Census data. Multivariable logistic regression models were used to analyse factors (diet, micronutrient deficiencies, haemoglobinopathies, sociodemographic factors, environment) associated with anaemia. Anaemia was present in 40% of girls and 18% of boys, equivalent to 72 million adolescents in 2018, and varied by region (girls 29%–46%; boys 11%–28%) and state (girls 7%–62%; boys 4%–32%). Iron deficiency (ferritin < 15 μg/L) was the strongest predictor of anaemia (odds ratio [OR]: 4.68, 95% confidence interval [CI]: [3.21,6.83]), followed by haemoglobinopathies (HbA2 > 3.5% or any HbS) (OR: 2.81, 95% CI: [1.66,4.74]), vitamin A deficiency (serum retinol <20 ng/ml) (OR: 1.86, 95% CI: [1.23,2.80]) and zinc deficiency (serum zinc < 70 μg/L) (OR: 1.32, 95% CI: [1.02,1.72]). Regional models show heterogeneity in the strength of association between factors and anaemia by region. Adolescent anaemia control programmes in India should continue to address iron deficiency, strengthen strategies to identify haemoglobinopathies and other micronutrient deficiencies, and further explore geographic variation in associated factors. 2022-10 2024-04-12T13:37:41Z 2024-04-12T13:37:41Z Journal Article https://hdl.handle.net/10568/141318 en Open Access Wiley Scott, Samuel; Lahiri, Anwesha; Sethi, Vani; de Wagt, Arjan; Menon, Purnima; Yadav, Kapil; Varghese, Mini; Joe, William; Vir, Sheila C.; and Nguyen, Phuong Hong. Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels. Maternal and Child Nutrition 18(4): e13391. https://doi.org/10.1111/mcn.13391
spellingShingle anaemia
adolescents
trace element deficiencies
trace elements
public health
Scott, Samuel P.
Lahiri, Anwesha
Sethi, Vani
de Wagt, Arjan
Menon, Purnima
Yadav, Kapil
Varghese, Mini
Joe, William
Vir, Sheila C.
Nguyen, Phuong Hong
Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title_full Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title_fullStr Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title_full_unstemmed Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title_short Anaemia in Indians aged 10–19 years: Prevalence, burden and associated factors at national and regional levels
title_sort anaemia in indians aged 10 19 years prevalence burden and associated factors at national and regional levels
topic anaemia
adolescents
trace element deficiencies
trace elements
public health
url https://hdl.handle.net/10568/141318
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