Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species

The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant developme...

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Main Author: Genome 10K community of scientists
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2009
Subjects:
Online Access:https://hdl.handle.net/10568/1411
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author Genome 10K community of scientists
author_browse Genome 10K community of scientists
author_facet Genome 10K community of scientists
author_sort Genome 10K community of scientists
collection Repository of Agricultural Research Outputs (CGSpace)
description The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant development of improved annotation technology and, therefore, propose to create a collection of tissue and DNA specimens for 10 000 vertebrate species specifically designated for whole-genome sequencing in the very near future. For this purpose, we, the Genome 10K Community of Scientists (G10KCOS), will assemble and allocate a biospecimen collection of some 16 203 representative vertebrate species spanning evolutionary diversity across living mammals, birds, nonavian reptiles, amphibians, and fishes (ca. 60 000 living species). In this proposal, we present precise counts for these 16 203 individual species with specimens presently tagged and stipulated for DNA sequencing by the G10KCOS. DNA sequencing has ushered in a new era of investigation in the biological sciences, allowing us to embark for the first time on a truly comprehensive study of vertebrate evolution, the results of which will touch nearly every aspect of vertebrate biological enquiry.
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spelling CGSpace14112023-12-08T19:36:04Z Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species Genome 10K community of scientists genetics vertebrates The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant development of improved annotation technology and, therefore, propose to create a collection of tissue and DNA specimens for 10 000 vertebrate species specifically designated for whole-genome sequencing in the very near future. For this purpose, we, the Genome 10K Community of Scientists (G10KCOS), will assemble and allocate a biospecimen collection of some 16 203 representative vertebrate species spanning evolutionary diversity across living mammals, birds, nonavian reptiles, amphibians, and fishes (ca. 60 000 living species). In this proposal, we present precise counts for these 16 203 individual species with specimens presently tagged and stipulated for DNA sequencing by the G10KCOS. DNA sequencing has ushered in a new era of investigation in the biological sciences, allowing us to embark for the first time on a truly comprehensive study of vertebrate evolution, the results of which will touch nearly every aspect of vertebrate biological enquiry. 2009-11-01 2010-05-07T11:09:24Z 2010-05-07T11:09:24Z Journal Article https://hdl.handle.net/10568/1411 en Open Access Oxford University Press Genome 10K Community of Scientists. 2009. Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species. Journal of Heredity 100(6):659-674.
spellingShingle genetics
vertebrates
Genome 10K community of scientists
Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title_full Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title_fullStr Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title_full_unstemmed Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title_short Genome 10K: a proposal to obtain whole-genome sequence for 10 000 vertebrate species
title_sort genome 10k a proposal to obtain whole genome sequence for 10 000 vertebrate species
topic genetics
vertebrates
url https://hdl.handle.net/10568/1411
work_keys_str_mv AT genome10kcommunityofscientists genome10kaproposaltoobtainwholegenomesequencefor10000vertebratespecies