First report of the emergence of peste des petits ruminants lineage IV virus in Senegal
Peste des petits ruminants (PPR) is a highly contagious viral disease and one of the deadliest affecting wild goats, sheep, and small ruminants; however, goats are generally more sensitive. The causative agent is the Peste des Petits Ruminants virus (PPRV), which is a single-stranded RNA virus of ne...
| Autores principales: | , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
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MDPI
2024
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| Acceso en línea: | https://hdl.handle.net/10568/139646 |
| _version_ | 1855534661018583040 |
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| author | Ba, A. Diop, G.L. Ndiaye, M. Dione, Michel M. Lo, M.M. |
| author_browse | Ba, A. Dione, Michel M. Diop, G.L. Lo, M.M. Ndiaye, M. |
| author_facet | Ba, A. Diop, G.L. Ndiaye, M. Dione, Michel M. Lo, M.M. |
| author_sort | Ba, A. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Peste des petits ruminants (PPR) is a highly contagious viral disease and one of the deadliest affecting wild goats, sheep, and small ruminants; however, goats are generally more sensitive. The causative agent is the Peste des Petits Ruminants virus (PPRV), which is a single-stranded RNA virus of negative polarity belonging to the Paramyxoviridae family. In February 2020, an active outbreak of PPR was reported in a herd of a transhumant farmer in the village of Gainth Pathé (department of Kounguel, Kaffrine region, Senegal). Of the ten swabs collected from the goats, eight returned a positive result through a quantitative real-time PCR. The sample that yielded the strongest signal from the quantitative real-time PCR was further analyzed with a conventional PCR amplification and direct amplicon sequencing. A phylogenetic analysis showed that the sequence of the PPR virus obtained belonged to lineage IV. These results confirm those found in the countries bordering Senegal and reinforce the hypothesis of the importance of animal mobility between these neighboring countries in the control of PPRV. In perspective, following the discovery of this lineage IV in Senegal, a study on its dispersion is underway throughout the national territory. The results that will emerge from this study, associated with detailed data on animal movements and epidemiological data, will provide appropriate and effective information to improve PPR surveillance and control strategies with a view to its eradication. |
| format | Journal Article |
| id | CGSpace139646 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1396462025-12-08T10:29:22Z First report of the emergence of peste des petits ruminants lineage IV virus in Senegal Ba, A. Diop, G.L. Ndiaye, M. Dione, Michel M. Lo, M.M. animal diseases pest of small ruminants small ruminants sheep goats Peste des petits ruminants (PPR) is a highly contagious viral disease and one of the deadliest affecting wild goats, sheep, and small ruminants; however, goats are generally more sensitive. The causative agent is the Peste des Petits Ruminants virus (PPRV), which is a single-stranded RNA virus of negative polarity belonging to the Paramyxoviridae family. In February 2020, an active outbreak of PPR was reported in a herd of a transhumant farmer in the village of Gainth Pathé (department of Kounguel, Kaffrine region, Senegal). Of the ten swabs collected from the goats, eight returned a positive result through a quantitative real-time PCR. The sample that yielded the strongest signal from the quantitative real-time PCR was further analyzed with a conventional PCR amplification and direct amplicon sequencing. A phylogenetic analysis showed that the sequence of the PPR virus obtained belonged to lineage IV. These results confirm those found in the countries bordering Senegal and reinforce the hypothesis of the importance of animal mobility between these neighboring countries in the control of PPRV. In perspective, following the discovery of this lineage IV in Senegal, a study on its dispersion is underway throughout the national territory. The results that will emerge from this study, associated with detailed data on animal movements and epidemiological data, will provide appropriate and effective information to improve PPR surveillance and control strategies with a view to its eradication. 2024-02-17 2024-02-24T14:06:20Z 2024-02-24T14:06:20Z Journal Article https://hdl.handle.net/10568/139646 en Open Access MDPI Ba, A., Diop, G.L., Ndiaye, M., Dione, M. and Lo, M.M. 2024. First report of the emergence of peste des petits ruminants lineage IV virus in Senegal. <i>Viruses</i> 16(2): 305. |
| spellingShingle | animal diseases pest of small ruminants small ruminants sheep goats Ba, A. Diop, G.L. Ndiaye, M. Dione, Michel M. Lo, M.M. First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title | First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title_full | First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title_fullStr | First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title_full_unstemmed | First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title_short | First report of the emergence of peste des petits ruminants lineage IV virus in Senegal |
| title_sort | first report of the emergence of peste des petits ruminants lineage iv virus in senegal |
| topic | animal diseases pest of small ruminants small ruminants sheep goats |
| url | https://hdl.handle.net/10568/139646 |
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