Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)

Abstract Apple scab disease, caused by the fungus Venturia inaequalis, endangers commercial apple production globally. It is predominantly managed by frequent fungicide sprays that can harm the environment and promote the development of fungicide-resistant strains. Cultivation of scab-resistant cult...

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Autores principales: Švara, Anže, De Storme, Nico, Carpentier, Sebastien, Keulemans, Wannes, De Coninck, Barbara
Formato: Journal Article
Lenguaje:Inglés
Publicado: Oxford University Press 2024
Materias:
Acceso en línea:https://hdl.handle.net/10568/138711
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author Švara, Anže
De Storme, Nico
Carpentier, Sebastien
Keulemans, Wannes
De Coninck, Barbara
author_browse Carpentier, Sebastien
De Coninck, Barbara
De Storme, Nico
Keulemans, Wannes
Švara, Anže
author_facet Švara, Anže
De Storme, Nico
Carpentier, Sebastien
Keulemans, Wannes
De Coninck, Barbara
author_sort Švara, Anže
collection Repository of Agricultural Research Outputs (CGSpace)
description Abstract Apple scab disease, caused by the fungus Venturia inaequalis, endangers commercial apple production globally. It is predominantly managed by frequent fungicide sprays that can harm the environment and promote the development of fungicide-resistant strains. Cultivation of scab-resistant cultivars harboring diverse qualitative Rvi resistance loci and quantitative trait loci associated with scab resistance could reduce the chemical footprint. A comprehensive understanding of the host-pathogen interaction is, however, needed to efficiently breed cultivars with enhanced resistance against a variety of pathogenic strains. Breeding efforts should not only encompass pyramiding of Rvi loci and their corresponding resistance alleles that directly or indirectly recognize pathogen effectors, but should also integrate genes that contribute to effective downstream defense mechanisms. This review provides an overview of the phenotypic and genetic aspects of apple scab resistance, and currently known corresponding defense mechanisms. Implementation of recent ‘-omics’ approaches has provided insights into the complex network of physiological, molecular and signaling processes that occur before and upon scab infection, thereby revealing the importance of both constitutive and induced defense mechanisms. Based on the current knowledge, we outline advances towards more efficient introgression of enhanced scab resistance into novel apple cultivars by conventional breeding or genetic modification techniques. However, additional studies integrating different ‘-omics’ approaches combined with functional studies will be necessary to unravel effective defense mechanisms as well as key regulatory genes underpinning scab resistance in apple. This crucial information will set the stage for successful knowledge-based breeding for enhanced scab resistance.
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spelling CGSpace1387112025-12-08T09:54:28Z Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica) Švara, Anže De Storme, Nico Carpentier, Sebastien Keulemans, Wannes De Coninck, Barbara phenotypic variation disease control phenotypes fruit crops Abstract Apple scab disease, caused by the fungus Venturia inaequalis, endangers commercial apple production globally. It is predominantly managed by frequent fungicide sprays that can harm the environment and promote the development of fungicide-resistant strains. Cultivation of scab-resistant cultivars harboring diverse qualitative Rvi resistance loci and quantitative trait loci associated with scab resistance could reduce the chemical footprint. A comprehensive understanding of the host-pathogen interaction is, however, needed to efficiently breed cultivars with enhanced resistance against a variety of pathogenic strains. Breeding efforts should not only encompass pyramiding of Rvi loci and their corresponding resistance alleles that directly or indirectly recognize pathogen effectors, but should also integrate genes that contribute to effective downstream defense mechanisms. This review provides an overview of the phenotypic and genetic aspects of apple scab resistance, and currently known corresponding defense mechanisms. Implementation of recent ‘-omics’ approaches has provided insights into the complex network of physiological, molecular and signaling processes that occur before and upon scab infection, thereby revealing the importance of both constitutive and induced defense mechanisms. Based on the current knowledge, we outline advances towards more efficient introgression of enhanced scab resistance into novel apple cultivars by conventional breeding or genetic modification techniques. However, additional studies integrating different ‘-omics’ approaches combined with functional studies will be necessary to unravel effective defense mechanisms as well as key regulatory genes underpinning scab resistance in apple. This crucial information will set the stage for successful knowledge-based breeding for enhanced scab resistance. 2024-02-06 2024-01-31T10:25:45Z 2024-01-31T10:25:45Z Journal Article https://hdl.handle.net/10568/138711 en Open Access Oxford University Press Švara, A.; De Storme, N.; Carpentier, S.; Keulemans, W.; De Coninck, B. (2024) Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (<i>Venturia inaequalis</i>) in apple cultivars (<i>Malus</i> × <i>domestica</i>). Horticulture Research 11(2): uhae002. ISSN: 2052-7276
spellingShingle phenotypic variation
disease control
phenotypes
fruit crops
Švara, Anže
De Storme, Nico
Carpentier, Sebastien
Keulemans, Wannes
De Coninck, Barbara
Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title_full Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title_fullStr Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title_full_unstemmed Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title_short Phenotyping, genetics and ‘-omics’ approaches to unravel and introgress enhanced resistance against apple scab (Venturia inaequalis) in apple cultivars (Malus x domestica)
title_sort phenotyping genetics and omics approaches to unravel and introgress enhanced resistance against apple scab venturia inaequalis in apple cultivars malus x domestica
topic phenotypic variation
disease control
phenotypes
fruit crops
url https://hdl.handle.net/10568/138711
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