Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease

Banana Xanthomonas wilt (BXW) caused by Xanthomonas campestris pv. musacearum (Xcm) is a severe bacterial disease devastating banana production in East and Central Africa, where banana is cultivated as a staple crop. Classical breeding of banana is challenging because the crop is clonally propagated...

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Main Authors: Adero, M.O., Tripathi, J., Oduor, R., Zipfel, C., Tripathi, L.
Format: Preprint
Language:Inglés
Published: Cold Spring Harbor Laboratory 2023
Subjects:
Online Access:https://hdl.handle.net/10568/131804
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author Adero, M.O.
Tripathi, J.
Oduor, R.
Zipfel, C.
Tripathi, L.
author_browse Adero, M.O.
Oduor, R.
Tripathi, J.
Tripathi, L.
Zipfel, C.
author_facet Adero, M.O.
Tripathi, J.
Oduor, R.
Zipfel, C.
Tripathi, L.
author_sort Adero, M.O.
collection Repository of Agricultural Research Outputs (CGSpace)
description Banana Xanthomonas wilt (BXW) caused by Xanthomonas campestris pv. musacearum (Xcm) is a severe bacterial disease devastating banana production in East and Central Africa, where banana is cultivated as a staple crop. Classical breeding of banana is challenging because the crop is clonally propagated and has limited genetic diversity. Thus, genetic engineering serves as a viable alternative for banana improvement. Several studies have shown that interfamily transfer of the elongation factor Tu receptor gene (AtEFR) from Arabidopsis thaliana to other plant families can increase broad-spectrum resistance against bacterial diseases. In this study, transgenic events of banana cultivar dwarf Cavendish expressing the AtEFR gene were generated and evaluated for resistance against Xcm under greenhouse conditions. The transgenic banana events were responsive to the EF-Tu-derived elf18 peptide and exhibited enhanced resistance to BXW disease compared to non-transgenic control plants. This study suggests that the functionality of AtEFR is retained in banana with the potential of enhancing resistance to BXW disease under field conditions.
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spelling CGSpace1318042025-11-11T10:10:25Z Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease Adero, M.O. Tripathi, J. Oduor, R. Zipfel, C. Tripathi, L. food security bananas xanthomonas campestris plant diseases varieties Banana Xanthomonas wilt (BXW) caused by Xanthomonas campestris pv. musacearum (Xcm) is a severe bacterial disease devastating banana production in East and Central Africa, where banana is cultivated as a staple crop. Classical breeding of banana is challenging because the crop is clonally propagated and has limited genetic diversity. Thus, genetic engineering serves as a viable alternative for banana improvement. Several studies have shown that interfamily transfer of the elongation factor Tu receptor gene (AtEFR) from Arabidopsis thaliana to other plant families can increase broad-spectrum resistance against bacterial diseases. In this study, transgenic events of banana cultivar dwarf Cavendish expressing the AtEFR gene were generated and evaluated for resistance against Xcm under greenhouse conditions. The transgenic banana events were responsive to the EF-Tu-derived elf18 peptide and exhibited enhanced resistance to BXW disease compared to non-transgenic control plants. This study suggests that the functionality of AtEFR is retained in banana with the potential of enhancing resistance to BXW disease under field conditions. 2023 2023-09-08T12:12:15Z 2023-09-08T12:12:15Z Preprint https://hdl.handle.net/10568/131804 en Open Access application/pdf Cold Spring Harbor Laboratory Adero, M.O., Tripathi, J., Odour, R., Zipfel, C. & Tripathi, L. (2023). Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in bananas enhances resistance against Xanthomonas campestris pv. musacearum. PLoS ONE 18(9): e0290884, 1-18.
spellingShingle food security
bananas
xanthomonas campestris
plant diseases
varieties
Adero, M.O.
Tripathi, J.
Oduor, R.
Zipfel, C.
Tripathi, L.
Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title_full Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title_fullStr Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title_full_unstemmed Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title_short Transgenic expression of Arabidopsis ELONGATION FACTOR-TU RECEPTOR (AtEFR) gene in banana enhances resistance to Banana Xanthomonas Wilt disease
title_sort transgenic expression of arabidopsis elongation factor tu receptor atefr gene in banana enhances resistance to banana xanthomonas wilt disease
topic food security
bananas
xanthomonas campestris
plant diseases
varieties
url https://hdl.handle.net/10568/131804
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