Effects of food-based approaches on vitamin A status of women and children: A Systematic Review
Abstract Background Vitamin A deficiency (VAD) increases risk for morbidity and mortality. Food-based approaches offer one strategy to improve vitamin A status. Objective This systematic review assessed evidence of the effects of food-based approaches on the vitamin A status of women and children u...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Elsevier
2023
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/131799 |
| _version_ | 1855522574744682496 |
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| author | Nankumbi, J. Grant, F. Sibeko, L. Mercado, E. O’Neil, K. Cordeiro, L.S. |
| author_browse | Cordeiro, L.S. Grant, F. Mercado, E. Nankumbi, J. O’Neil, K. Sibeko, L. |
| author_facet | Nankumbi, J. Grant, F. Sibeko, L. Mercado, E. O’Neil, K. Cordeiro, L.S. |
| author_sort | Nankumbi, J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Abstract
Background
Vitamin A deficiency (VAD) increases risk for morbidity and mortality. Food-based approaches offer one strategy to improve vitamin A status.
Objective
This systematic review assessed evidence of the effects of food-based approaches on the vitamin A status of women and children under five years.
Methods
VAD was defined as clinical ocular symptoms, such as loss of vision, and/or retinol plasma or serum concentration <0.70 μmol/L. Searches on food-based approaches to improve vitamin A status were conducted for the period 2011-2022 on PubMed, CINHAL, Web of Science, and Google Scholar using PRISMA guidelines. English language publications were included. Case studies, unpublished dissertations, and non-peer-reviewed studies were excluded.
Results
This review comprises 24 of 27,322 identified studies; 23 included studies focused on provitamin A carotenoids. There were 17, 214 participants across the 24 studies with sample sizes ranging from 8 to 3571 individuals. Intervention studies spanned from three weeks to two years. Fifteen (63%) studies were randomized control trials, seven were cross-sectional, and two were longitudinal studies. Most studies (N = 21) used biochemical measurements, e.g. serum retinol, to assess vitamin A status; other studies used clinical symptoms (e.g. xerophtalmia) or dietary intake. Thirteen (54%) studies reported a statistically significant effect of food-based interventions (N = 8) or an association of diet (N= 5) on vitamin A status.
Conclusions
This systematic review indicated that some food-based interventions improved vitamin A status, thus offering a safe and effective delivery mechanism for vitamin A. There appeared to be significant association between vitamin A status and consumption of foods with high concentrations of preformed vitamin A and provitamin A carotenoids. Differences across studies in regard to the period of evaluation, food approaches used, and statistical power may explain the lack of effectiveness of food-based approaches on vitamin A status in some studies. |
| format | Journal Article |
| id | CGSpace131799 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace1317992025-12-08T10:06:44Z Effects of food-based approaches on vitamin A status of women and children: A Systematic Review Nankumbi, J. Grant, F. Sibeko, L. Mercado, E. O’Neil, K. Cordeiro, L.S. vitamin a deficiency women children foods Abstract Background Vitamin A deficiency (VAD) increases risk for morbidity and mortality. Food-based approaches offer one strategy to improve vitamin A status. Objective This systematic review assessed evidence of the effects of food-based approaches on the vitamin A status of women and children under five years. Methods VAD was defined as clinical ocular symptoms, such as loss of vision, and/or retinol plasma or serum concentration <0.70 μmol/L. Searches on food-based approaches to improve vitamin A status were conducted for the period 2011-2022 on PubMed, CINHAL, Web of Science, and Google Scholar using PRISMA guidelines. English language publications were included. Case studies, unpublished dissertations, and non-peer-reviewed studies were excluded. Results This review comprises 24 of 27,322 identified studies; 23 included studies focused on provitamin A carotenoids. There were 17, 214 participants across the 24 studies with sample sizes ranging from 8 to 3571 individuals. Intervention studies spanned from three weeks to two years. Fifteen (63%) studies were randomized control trials, seven were cross-sectional, and two were longitudinal studies. Most studies (N = 21) used biochemical measurements, e.g. serum retinol, to assess vitamin A status; other studies used clinical symptoms (e.g. xerophtalmia) or dietary intake. Thirteen (54%) studies reported a statistically significant effect of food-based interventions (N = 8) or an association of diet (N= 5) on vitamin A status. Conclusions This systematic review indicated that some food-based interventions improved vitamin A status, thus offering a safe and effective delivery mechanism for vitamin A. There appeared to be significant association between vitamin A status and consumption of foods with high concentrations of preformed vitamin A and provitamin A carotenoids. Differences across studies in regard to the period of evaluation, food approaches used, and statistical power may explain the lack of effectiveness of food-based approaches on vitamin A status in some studies. 2023-11 2023-09-07T20:17:09Z 2023-09-07T20:17:09Z Journal Article https://hdl.handle.net/10568/131799 en Open Access Elsevier Nankumbi, J.; Grant, F.; Sibeko, L.; Mercado, E.; O’Neil, K.; Cordeiro, L. 2023. Effects of food-based approaches on vitamin A status of women and children: A Systematic Review. Advances in Nutrition. ISSN 2156-5376. |
| spellingShingle | vitamin a deficiency women children foods Nankumbi, J. Grant, F. Sibeko, L. Mercado, E. O’Neil, K. Cordeiro, L.S. Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title | Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title_full | Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title_fullStr | Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title_full_unstemmed | Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title_short | Effects of food-based approaches on vitamin A status of women and children: A Systematic Review |
| title_sort | effects of food based approaches on vitamin a status of women and children a systematic review |
| topic | vitamin a deficiency women children foods |
| url | https://hdl.handle.net/10568/131799 |
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