A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations

A structural variant (SV) in the agouti signaling protein gene (ASIP), namely ASIP‐SV1, has been found to strongly correlate with the darkness of hair coat in specific regions of the body of bulls from the zebu (Bos indicus) Nellore breed. Here we visually analyzed the whole‐genome sequence of zebu...

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Autores principales: Trigo, B.B., Alves, N.F., Milanesi, M., Garcia, J.F., Terefe, Endashaw, Hanotte, Olivier H., Tijjani, Abdulfatai, Utsunomiya, Y.T.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2023
Materias:
Acceso en línea:https://hdl.handle.net/10568/130860
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author Trigo, B.B.
Alves, N.F.
Milanesi, M.
Garcia, J.F.
Terefe, Endashaw
Hanotte, Olivier H.
Tijjani, Abdulfatai
Utsunomiya, Y.T.
author_browse Alves, N.F.
Garcia, J.F.
Hanotte, Olivier H.
Milanesi, M.
Terefe, Endashaw
Tijjani, Abdulfatai
Trigo, B.B.
Utsunomiya, Y.T.
author_facet Trigo, B.B.
Alves, N.F.
Milanesi, M.
Garcia, J.F.
Terefe, Endashaw
Hanotte, Olivier H.
Tijjani, Abdulfatai
Utsunomiya, Y.T.
author_sort Trigo, B.B.
collection Repository of Agricultural Research Outputs (CGSpace)
description A structural variant (SV) in the agouti signaling protein gene (ASIP), namely ASIP‐SV1, has been found to strongly correlate with the darkness of hair coat in specific regions of the body of bulls from the zebu (Bos indicus) Nellore breed. Here we visually analyzed the whole‐genome sequence of zebu and taurine (Bos taurus) cattle to elucidate the extent of spread of ASIP‐SV1 in different cattle populations. Of 216 sequences analyzed, 63 zebu (45.9%) and five taurine (6.3%) animals had at least one copy of ASIP‐SV1. Four of the taurine animals presenting the SV were Romagnola cattle, a breed with history of zebu introgression. The remaining taurine animal was a Simmental, a breed frequently used in crossbreeding. These data provide evidence that ASIP‐SV1 is commonly found in zebu populations, in addition to taurine animals with zebu admixture.
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spelling CGSpace1308602024-08-27T10:37:14Z A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations Trigo, B.B. Alves, N.F. Milanesi, M. Garcia, J.F. Terefe, Endashaw Hanotte, Olivier H. Tijjani, Abdulfatai Utsunomiya, Y.T. zebu cattle bos indicus bos taurus breeds animal breeding genetics A structural variant (SV) in the agouti signaling protein gene (ASIP), namely ASIP‐SV1, has been found to strongly correlate with the darkness of hair coat in specific regions of the body of bulls from the zebu (Bos indicus) Nellore breed. Here we visually analyzed the whole‐genome sequence of zebu and taurine (Bos taurus) cattle to elucidate the extent of spread of ASIP‐SV1 in different cattle populations. Of 216 sequences analyzed, 63 zebu (45.9%) and five taurine (6.3%) animals had at least one copy of ASIP‐SV1. Four of the taurine animals presenting the SV were Romagnola cattle, a breed with history of zebu introgression. The remaining taurine animal was a Simmental, a breed frequently used in crossbreeding. These data provide evidence that ASIP‐SV1 is commonly found in zebu populations, in addition to taurine animals with zebu admixture. 2023-08 2023-06-26T08:56:46Z 2023-06-26T08:56:46Z Journal Article https://hdl.handle.net/10568/130860 en Limited Access Wiley Trigo, B.B., Alves, N.F., Milanesi, M., Garcia, J.F., Terefe, E., Hanotte, O., Tijjani, A. and Utsunomiya, Y.T. 2023. A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations. Animal Genetics
spellingShingle zebu
cattle
bos indicus
bos taurus
breeds
animal breeding
genetics
Trigo, B.B.
Alves, N.F.
Milanesi, M.
Garcia, J.F.
Terefe, Endashaw
Hanotte, Olivier H.
Tijjani, Abdulfatai
Utsunomiya, Y.T.
A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title_full A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title_fullStr A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title_full_unstemmed A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title_short A structural variant at ASIP associated with the darkness of hair coat is found in multiple zebu cattle populations
title_sort structural variant at asip associated with the darkness of hair coat is found in multiple zebu cattle populations
topic zebu
cattle
bos indicus
bos taurus
breeds
animal breeding
genetics
url https://hdl.handle.net/10568/130860
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