Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia
The objective of this study was to characterize the distribution of antimicrobial resistance (AMR) of Escherichia coli (E. coli) isolated from livestock feces and soil in smallholder livestock systems. A cross-sectional study was carried out sampling 77 randomly selected households in four districts...
| Autores principales: | , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/130525 |
| _version_ | 1855525795266560000 |
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| author | Gemeda, Biruk A. Wieland, Barbara Alemayehu, Gezahegn Knight-Jones, Theodore J.D. Wodajo, Hiwot D. Tefera, M. Kumbe, A. Olani, A. Abera, S. Amenu, Kebede |
| author_browse | Abera, S. Alemayehu, Gezahegn Amenu, Kebede Gemeda, Biruk A. Knight-Jones, Theodore J.D. Kumbe, A. Olani, A. Tefera, M. Wieland, Barbara Wodajo, Hiwot D. |
| author_facet | Gemeda, Biruk A. Wieland, Barbara Alemayehu, Gezahegn Knight-Jones, Theodore J.D. Wodajo, Hiwot D. Tefera, M. Kumbe, A. Olani, A. Abera, S. Amenu, Kebede |
| author_sort | Gemeda, Biruk A. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | The objective of this study was to characterize the distribution of antimicrobial resistance (AMR) of Escherichia coli (E. coli) isolated from livestock feces and soil in smallholder livestock systems. A cross-sectional study was carried out sampling 77 randomly selected households in four districts representing two agroecologies and production systems. E. coli was isolated and the susceptibility to 15 antimicrobials was assessed. Of 462 E. coli isolates tested, resistance to at least one antimicrobial was detected in 52% (43.7–60.8) of isolates from cattle fecal samples, 34% (95% CI, 26.2–41.8) from sheep samples, 58% (95% CI, 47.9–68.2) from goat samples and 53% (95% CI, 43.2–62.4) from soil samples. AMR patterns for E. coli from livestock and soil showed some similarities, with the highest prevalence of resistance detected against streptomycin (33%), followed by amoxycillin/clavulanate (23%) and tetracycline (8%). The odds of detecting E. coli resistance to ≥2 antimicrobials in livestock fecal samples were nearly three times (Odd Ratio—OR: 2.9; 95% CI, 1.72–5.17; p = 0.000) higher in lowland pastoral than in highland mixed crop–livestock production systems. These findings provide insights into the status of resistance in livestock and soil, and associated risk factors in low-resource settings in Ethiopia. |
| format | Journal Article |
| id | CGSpace130525 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1305252025-12-08T10:29:22Z Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia Gemeda, Biruk A. Wieland, Barbara Alemayehu, Gezahegn Knight-Jones, Theodore J.D. Wodajo, Hiwot D. Tefera, M. Kumbe, A. Olani, A. Abera, S. Amenu, Kebede antimicrobial resistance animal production livestock The objective of this study was to characterize the distribution of antimicrobial resistance (AMR) of Escherichia coli (E. coli) isolated from livestock feces and soil in smallholder livestock systems. A cross-sectional study was carried out sampling 77 randomly selected households in four districts representing two agroecologies and production systems. E. coli was isolated and the susceptibility to 15 antimicrobials was assessed. Of 462 E. coli isolates tested, resistance to at least one antimicrobial was detected in 52% (43.7–60.8) of isolates from cattle fecal samples, 34% (95% CI, 26.2–41.8) from sheep samples, 58% (95% CI, 47.9–68.2) from goat samples and 53% (95% CI, 43.2–62.4) from soil samples. AMR patterns for E. coli from livestock and soil showed some similarities, with the highest prevalence of resistance detected against streptomycin (33%), followed by amoxycillin/clavulanate (23%) and tetracycline (8%). The odds of detecting E. coli resistance to ≥2 antimicrobials in livestock fecal samples were nearly three times (Odd Ratio—OR: 2.9; 95% CI, 1.72–5.17; p = 0.000) higher in lowland pastoral than in highland mixed crop–livestock production systems. These findings provide insights into the status of resistance in livestock and soil, and associated risk factors in low-resource settings in Ethiopia. 2023-05-22 2023-05-30T12:28:06Z 2023-05-30T12:28:06Z Journal Article https://hdl.handle.net/10568/130525 en Open Access MDPI Gemeda, B.A., Wieland, B., Alemayehu, G., Knight-Jones, T.J.D., Wodajo, H.D., Tefera, M., Kumbe, A., Olani, A., Abera, S. and Amenu, K. 2023. Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia. Antibiotics 12(5): 941. |
| spellingShingle | antimicrobial resistance animal production livestock Gemeda, Biruk A. Wieland, Barbara Alemayehu, Gezahegn Knight-Jones, Theodore J.D. Wodajo, Hiwot D. Tefera, M. Kumbe, A. Olani, A. Abera, S. Amenu, Kebede Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title | Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title_full | Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title_fullStr | Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title_full_unstemmed | Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title_short | Antimicrobial resistance of Escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in Ethiopia |
| title_sort | antimicrobial resistance of escherichia coli isolates from livestock and the environment in extensive smallholder livestock production systems in ethiopia |
| topic | antimicrobial resistance animal production livestock |
| url | https://hdl.handle.net/10568/130525 |
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