Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes

Background Musa beccarii (Musaceae) is a banana species native to Borneo, sometimes grown as an ornamental plant. The basic chromosome number of Musa species is x = 7, 10, or 11; however, M. beccarii has a basic chromosome number of x = 9 (2n = 2x = 18), which is the same basic chromosome number...

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Autores principales: Wang, Zheng-Feng, Rouard, Mathieu, Droc, Gaëtan, Heslop-Harrison, J.S., Ge, Xue-Jun
Formato: Journal Article
Lenguaje:Inglés
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://hdl.handle.net/10568/129634
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author Wang, Zheng-Feng
Rouard, Mathieu
Droc, Gaëtan
Heslop-Harrison, J.S.
Ge, Xue-Jun
author_browse Droc, Gaëtan
Ge, Xue-Jun
Heslop-Harrison, J.S.
Rouard, Mathieu
Wang, Zheng-Feng
author_facet Wang, Zheng-Feng
Rouard, Mathieu
Droc, Gaëtan
Heslop-Harrison, J.S.
Ge, Xue-Jun
author_sort Wang, Zheng-Feng
collection Repository of Agricultural Research Outputs (CGSpace)
description Background Musa beccarii (Musaceae) is a banana species native to Borneo, sometimes grown as an ornamental plant. The basic chromosome number of Musa species is x = 7, 10, or 11; however, M. beccarii has a basic chromosome number of x = 9 (2n = 2x = 18), which is the same basic chromosome number of species in the sister genera Ensete and Musella. Musa beccarii is in the section Callimusa, which is sister to the section Musa. We generated a high-quality chromosome-scale genome assembly of M. beccarii to better understand the evolution and diversity of genomes within the family Musaceae. Findings The M. beccarii genome was assembled by long-read and Hi-C sequencing, and genes were annotated using both long Iso-seq and short RNA-seq reads. The size of M. beccarii was the largest among all known Musaceae assemblies (∼570 Mbp) due to the expansion of transposable elements and increased 45S ribosomal DNA sites. By synteny analysis, we detected extensive genome-wide chromosome fusions and fissions between M. beccarii and the other Musa and Ensete species, far beyond those expected from differences in chromosome number. Within Musaceae, M. beccarii showed a reduced number of terpenoid synthase genes, which are related to chemical defense, and enrichment in lipid metabolism genes linked to the physical defense of the cell wall. Furthermore, type III polyketide synthase was the most abundant biosynthetic gene cluster (BGC) in M. beccarii. BGCs were not conserved in Musaceae genomes. Conclusions The genome assembly of M. beccarii is the first chromosome-scale genome assembly in the Callimusa section in Musa, which provides an important genetic resource that aids our understanding of the evolution of Musaceae genomes and enhances our knowledge of the pangenome.
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spelling CGSpace1296342025-11-11T18:48:32Z Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes Wang, Zheng-Feng Rouard, Mathieu Droc, Gaëtan Heslop-Harrison, J.S. Ge, Xue-Jun genome annotation evolution musa wild plants genomes bioinformatics data analysis transcriptomics Background Musa beccarii (Musaceae) is a banana species native to Borneo, sometimes grown as an ornamental plant. The basic chromosome number of Musa species is x = 7, 10, or 11; however, M. beccarii has a basic chromosome number of x = 9 (2n = 2x = 18), which is the same basic chromosome number of species in the sister genera Ensete and Musella. Musa beccarii is in the section Callimusa, which is sister to the section Musa. We generated a high-quality chromosome-scale genome assembly of M. beccarii to better understand the evolution and diversity of genomes within the family Musaceae. Findings The M. beccarii genome was assembled by long-read and Hi-C sequencing, and genes were annotated using both long Iso-seq and short RNA-seq reads. The size of M. beccarii was the largest among all known Musaceae assemblies (∼570 Mbp) due to the expansion of transposable elements and increased 45S ribosomal DNA sites. By synteny analysis, we detected extensive genome-wide chromosome fusions and fissions between M. beccarii and the other Musa and Ensete species, far beyond those expected from differences in chromosome number. Within Musaceae, M. beccarii showed a reduced number of terpenoid synthase genes, which are related to chemical defense, and enrichment in lipid metabolism genes linked to the physical defense of the cell wall. Furthermore, type III polyketide synthase was the most abundant biosynthetic gene cluster (BGC) in M. beccarii. BGCs were not conserved in Musaceae genomes. Conclusions The genome assembly of M. beccarii is the first chromosome-scale genome assembly in the Callimusa section in Musa, which provides an important genetic resource that aids our understanding of the evolution of Musaceae genomes and enhances our knowledge of the pangenome. 2022-12-28 2023-03-14T09:19:43Z 2023-03-14T09:19:43Z Journal Article https://hdl.handle.net/10568/129634 en Open Access application/pdf Oxford University Press Wang, Z-F.; Rouard, M.; Droc, G.; Heslop-Harrison, P. Ge, X-J. (2023) Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes. GigaScience 12: giad005. ISSN: 2047-217X
spellingShingle genome annotation
evolution
musa
wild plants
genomes
bioinformatics
data analysis
transcriptomics
Wang, Zheng-Feng
Rouard, Mathieu
Droc, Gaëtan
Heslop-Harrison, J.S.
Ge, Xue-Jun
Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title_full Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title_fullStr Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title_full_unstemmed Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title_short Genome assembly of Musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of Musaceae genomes
title_sort genome assembly of musa beccarii shows extensive chromosomal rearrangements and genome expansion during evolution of musaceae genomes
topic genome annotation
evolution
musa
wild plants
genomes
bioinformatics
data analysis
transcriptomics
url https://hdl.handle.net/10568/129634
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