Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)

Powdery mildew is a devastating foliar disease occurring in most wheat-growing areas. Characterization and fine mapping of genes for powdery mildew resistance can benefit marker-assisted breeding. We previously identified a stable quantitative trait locus (QTL) QPm.caas-3BS for adult-plant resistanc...

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Main Authors: Yan Dong, Dengan Xu, Xiaowan Xu, Yan Ren, Fengmei Gao, Jie Song, Aolin Jia, Yuanfeng Hao, He Zhonghu, Xianchun Xia
Format: Journal Article
Language:Inglés
Published: Springer 2022
Subjects:
Online Access:https://hdl.handle.net/10568/129094
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author Yan Dong
Dengan Xu
Xiaowan Xu
Yan Ren
Fengmei Gao
Jie Song
Aolin Jia
Yuanfeng Hao
He Zhonghu
Xianchun Xia
author_browse Aolin Jia
Dengan Xu
Fengmei Gao
He Zhonghu
Jie Song
Xianchun Xia
Xiaowan Xu
Yan Dong
Yan Ren
Yuanfeng Hao
author_facet Yan Dong
Dengan Xu
Xiaowan Xu
Yan Ren
Fengmei Gao
Jie Song
Aolin Jia
Yuanfeng Hao
He Zhonghu
Xianchun Xia
author_sort Yan Dong
collection Repository of Agricultural Research Outputs (CGSpace)
description Powdery mildew is a devastating foliar disease occurring in most wheat-growing areas. Characterization and fine mapping of genes for powdery mildew resistance can benefit marker-assisted breeding. We previously identified a stable quantitative trait locus (QTL) QPm.caas-3BS for adult-plant resistance to powdery mildew in a recombinant inbred line population of Zhou8425B/Chinese Spring by phenotyping across four environments. Using 11 heterozygous recombinants and high-density molecular markers, QPm.caas-3BS was delimited in a physical interval of approximately 3.91 Mb. Based on re-sequenced data and expression profiles, three genes TraesCS3B02G014800, TraesCS3B02G016800 and TraesCS3B02G019900 were associated with the powdery mildew resistance locus. Three gene-specific kompetitive allele-specific PCR (KASP) markers were developed from these genes and validated in the Zhou8425B derivatives and Zhou8425B/Chinese Spring population in which the resistance gene was mapped to a 0.3 cM interval flanked by KASP14800 and snp_50465, corresponding to a 431 kb region at the distal end of chromosome 3BS. Within the interval, TraesCS3B02G014800 was the most likely candidate gene for QPm.caas-3BS, but TraesCS3B02G016300 and TraesCS3B02G016400 were less likely candidates based on gene annotations and sequence variation between the parents. These results not only offer high-throughput KASP markers for improvement of powdery mildew resistance but also pave the way to map-based cloning of the resistance gene.
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spelling CGSpace1290942025-03-11T12:14:31Z Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.) Yan Dong Dengan Xu Xiaowan Xu Yan Ren Fengmei Gao Jie Song Aolin Jia Yuanfeng Hao He Zhonghu Xianchun Xia quantitative trait loci disease resistance adult plant resistance powdery mildews wheat Powdery mildew is a devastating foliar disease occurring in most wheat-growing areas. Characterization and fine mapping of genes for powdery mildew resistance can benefit marker-assisted breeding. We previously identified a stable quantitative trait locus (QTL) QPm.caas-3BS for adult-plant resistance to powdery mildew in a recombinant inbred line population of Zhou8425B/Chinese Spring by phenotyping across four environments. Using 11 heterozygous recombinants and high-density molecular markers, QPm.caas-3BS was delimited in a physical interval of approximately 3.91 Mb. Based on re-sequenced data and expression profiles, three genes TraesCS3B02G014800, TraesCS3B02G016800 and TraesCS3B02G019900 were associated with the powdery mildew resistance locus. Three gene-specific kompetitive allele-specific PCR (KASP) markers were developed from these genes and validated in the Zhou8425B derivatives and Zhou8425B/Chinese Spring population in which the resistance gene was mapped to a 0.3 cM interval flanked by KASP14800 and snp_50465, corresponding to a 431 kb region at the distal end of chromosome 3BS. Within the interval, TraesCS3B02G014800 was the most likely candidate gene for QPm.caas-3BS, but TraesCS3B02G016300 and TraesCS3B02G016400 were less likely candidates based on gene annotations and sequence variation between the parents. These results not only offer high-throughput KASP markers for improvement of powdery mildew resistance but also pave the way to map-based cloning of the resistance gene. 2022-03 2023-02-28T09:00:03Z 2023-02-28T09:00:03Z Journal Article https://hdl.handle.net/10568/129094 en Limited Access Springer Dong, Y., Xu, D., Xu, X., Ren, Y., Gao, F., Song, J., Jia, A., Hao, Y., He, Z. and Xia, X. 202). Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.). Theoretical and Applied Genetics 135(3):1083–1099
spellingShingle quantitative trait loci
disease resistance
adult plant resistance
powdery mildews
wheat
Yan Dong
Dengan Xu
Xiaowan Xu
Yan Ren
Fengmei Gao
Jie Song
Aolin Jia
Yuanfeng Hao
He Zhonghu
Xianchun Xia
Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title_full Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title_fullStr Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title_full_unstemmed Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title_short Fine mapping of QPm.caas-3BS, a stable QTL for adult-plant resistance to powdery mildew in wheat (Triticum aestivum L.)
title_sort fine mapping of qpm caas 3bs a stable qtl for adult plant resistance to powdery mildew in wheat triticum aestivum l
topic quantitative trait loci
disease resistance
adult plant resistance
powdery mildews
wheat
url https://hdl.handle.net/10568/129094
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