Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL

Thousand kernel weight (TKW) is an important yield component trait in wheat, and identification of the underlying genetic loci is helpful for yield improvement. We previously identified a stable quantitative trait locus (QTL) QTKW.caas-5DL for TKW in a Doumai/Shi4185 recombinant inbred line (RIL) po...

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Main Authors: Jie Song, Dengan Xu, Yan Dong, Faji Li, Bian, Yingjie, Lingling Li, Xumei Luo, Fei, Shuaipeng, Lei Li, Cong Zhao, Yong Zhang, Xianchun Xia, Zhongfu Ni, He Zhonghu, Shuanghe Cao
Format: Journal Article
Language:Inglés
Published: Springer 2022
Subjects:
Online Access:https://hdl.handle.net/10568/129062
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author Jie Song
Dengan Xu
Yan Dong
Faji Li
Bian, Yingjie
Lingling Li
Xumei Luo
Fei, Shuaipeng
Lei Li
Cong Zhao
Yong Zhang
Xianchun Xia
Zhongfu Ni
He Zhonghu
Shuanghe Cao
author_browse Bian, Yingjie
Cong Zhao
Dengan Xu
Faji Li
Fei, Shuaipeng
He Zhonghu
Jie Song
Lei Li
Lingling Li
Shuanghe Cao
Xianchun Xia
Xumei Luo
Yan Dong
Yong Zhang
Zhongfu Ni
author_facet Jie Song
Dengan Xu
Yan Dong
Faji Li
Bian, Yingjie
Lingling Li
Xumei Luo
Fei, Shuaipeng
Lei Li
Cong Zhao
Yong Zhang
Xianchun Xia
Zhongfu Ni
He Zhonghu
Shuanghe Cao
author_sort Jie Song
collection Repository of Agricultural Research Outputs (CGSpace)
description Thousand kernel weight (TKW) is an important yield component trait in wheat, and identification of the underlying genetic loci is helpful for yield improvement. We previously identified a stable quantitative trait locus (QTL) QTKW.caas-5DL for TKW in a Doumai/Shi4185 recombinant inbred line (RIL) population. Here we performed fine mapping of QTKW.caas-5DL using secondary populations derived from 15 heterozygous recombinants and delimited the QTL to an approximate 3.9 Mb physical interval from 409.9 to 413.8 Mb according to the Chinese Spring (CS) reference genome. Analysis of genomic synteny showed that annotated genes in the physical interval had high collinearity among CS and eight other wheat genomes. Seven genes with sequence variation and/or differential expression between parents were predicted as candidates for QTKW.caas-5DL based on whole-genome resequencing and transcriptome assays. A kompetitive allele-specific PCR (KASP) marker for QTKW.caas-5DL was developed, and genotyping confirmed a significant association with TKW but not with other yield component traits in a panel of elite wheat cultivars. The superior allele of QTKW.caas-5DL was frequent in a panel of cultivars, suggesting that it had undergone positive selection. These findings not only lay a foundation for map-based cloning of QTKW.caas-5DL but also provide an efficient tool for marker-assisted selection.
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spelling CGSpace1290622025-03-11T12:14:31Z Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL Jie Song Dengan Xu Yan Dong Faji Li Bian, Yingjie Lingling Li Xumei Luo Fei, Shuaipeng Lei Li Cong Zhao Yong Zhang Xianchun Xia Zhongfu Ni He Zhonghu Shuanghe Cao quantitative trait loci wheat yields improvement genomes marker-assisted selection Thousand kernel weight (TKW) is an important yield component trait in wheat, and identification of the underlying genetic loci is helpful for yield improvement. We previously identified a stable quantitative trait locus (QTL) QTKW.caas-5DL for TKW in a Doumai/Shi4185 recombinant inbred line (RIL) population. Here we performed fine mapping of QTKW.caas-5DL using secondary populations derived from 15 heterozygous recombinants and delimited the QTL to an approximate 3.9 Mb physical interval from 409.9 to 413.8 Mb according to the Chinese Spring (CS) reference genome. Analysis of genomic synteny showed that annotated genes in the physical interval had high collinearity among CS and eight other wheat genomes. Seven genes with sequence variation and/or differential expression between parents were predicted as candidates for QTKW.caas-5DL based on whole-genome resequencing and transcriptome assays. A kompetitive allele-specific PCR (KASP) marker for QTKW.caas-5DL was developed, and genotyping confirmed a significant association with TKW but not with other yield component traits in a panel of elite wheat cultivars. The superior allele of QTKW.caas-5DL was frequent in a panel of cultivars, suggesting that it had undergone positive selection. These findings not only lay a foundation for map-based cloning of QTKW.caas-5DL but also provide an efficient tool for marker-assisted selection. 2022-09 2023-02-26T17:36:13Z 2023-02-26T17:36:13Z Journal Article https://hdl.handle.net/10568/129062 en Limited Access Springer Song, J., Xu, D., Dong, Y., Li, F., Bian, Y., Li, L., Luo, X., Fei, S., Li, L., Zhao, C., Zhang, Y., Xia, X., Ni, Z., He, Z. and Cao, S. 2022. Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL. Theoretical and Applied Genetics 135(9):3237–3246.
spellingShingle quantitative trait loci
wheat
yields
improvement
genomes
marker-assisted selection
Jie Song
Dengan Xu
Yan Dong
Faji Li
Bian, Yingjie
Lingling Li
Xumei Luo
Fei, Shuaipeng
Lei Li
Cong Zhao
Yong Zhang
Xianchun Xia
Zhongfu Ni
He Zhonghu
Shuanghe Cao
Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title_full Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title_fullStr Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title_full_unstemmed Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title_short Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL
title_sort fine mapping and characterization of a major qtl for grain weight on wheat chromosome arm 5dl
topic quantitative trait loci
wheat
yields
improvement
genomes
marker-assisted selection
url https://hdl.handle.net/10568/129062
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