Exploring genetic diversity and selection signatures in indigenous African cattle breeds
African cattle are a fascinating resource for exploration of genetic diversity due to their complex history and their adaptation to diverse environments. As a consequence of taurine and indicine ancestries and selection pressure from various environments as well as from humans, over 150 African catt...
| Autores principales: | , , , , , |
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
Wageningen University & Research
2022
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/128739 |
| _version_ | 1855531087911976960 |
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| author | Friedrich, J. Bailey, R. Talenti, A. Marshall, Karen Prendergast, J. Wiener, P. |
| author_browse | Bailey, R. Friedrich, J. Marshall, Karen Prendergast, J. Talenti, A. Wiener, P. |
| author_facet | Friedrich, J. Bailey, R. Talenti, A. Marshall, Karen Prendergast, J. Wiener, P. |
| author_sort | Friedrich, J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | African cattle are a fascinating resource for exploration of genetic diversity due to their complex history and their adaptation to diverse environments. As a consequence of taurine and indicine ancestries and selection pressure from various environments as well as from humans, over 150 African cattle breeds exist today with remarkable genotypic and phenotypic diversity. We analysed whole-genome sequence data of over 100 African cattle comprising 9 breeds and calculated within- and between-breed population statistics to characterise genetic diversity and identify selection signatures. We found overlapping selection signatures between indigenous African breeds, with the longest selection signature on BTA10. The greatest genetic differentiation from other breeds was observed for the N?Dama and Boran breeds, potentially mirroring their high proportion of taurine and indicine ancestry, respectively. Genomic regions that are highly differentiated between breeds suggest candidate regions for associations with important adaptation and production traits. |
| format | Book Chapter |
| id | CGSpace128739 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Wageningen University & Research |
| publisherStr | Wageningen University & Research |
| record_format | dspace |
| spelling | CGSpace1287392024-01-12T10:00:54Z Exploring genetic diversity and selection signatures in indigenous African cattle breeds Friedrich, J. Bailey, R. Talenti, A. Marshall, Karen Prendergast, J. Wiener, P. genetics animal breeding African cattle are a fascinating resource for exploration of genetic diversity due to their complex history and their adaptation to diverse environments. As a consequence of taurine and indicine ancestries and selection pressure from various environments as well as from humans, over 150 African cattle breeds exist today with remarkable genotypic and phenotypic diversity. We analysed whole-genome sequence data of over 100 African cattle comprising 9 breeds and calculated within- and between-breed population statistics to characterise genetic diversity and identify selection signatures. We found overlapping selection signatures between indigenous African breeds, with the longest selection signature on BTA10. The greatest genetic differentiation from other breeds was observed for the N?Dama and Boran breeds, potentially mirroring their high proportion of taurine and indicine ancestry, respectively. Genomic regions that are highly differentiated between breeds suggest candidate regions for associations with important adaptation and production traits. 2022-12-31 2023-02-20T11:13:45Z 2023-02-20T11:13:45Z Book Chapter https://hdl.handle.net/10568/128739 en Open Access Wageningen University & Research Friedrich, J., Bailey, R., Talenti, A., Marshall, K., Prendergast, J. and Wiener, P. 2023. Exploring genetic diversity and selection signatures in indigenous African cattle breeds. IN: Veerkamp, R.F. and Haas, Y. de. (eds), Proceedings of the 12th World Congress on Genetics Applied to Livestock Production (WCGALP): Technical and species orientated innovations in animal breeding, and contribution of genetics to solving societal challenges. Wageningen, the Netherlands: Wageningen Academic Publishers: 810-813. |
| spellingShingle | genetics animal breeding Friedrich, J. Bailey, R. Talenti, A. Marshall, Karen Prendergast, J. Wiener, P. Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title | Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title_full | Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title_fullStr | Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title_full_unstemmed | Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title_short | Exploring genetic diversity and selection signatures in indigenous African cattle breeds |
| title_sort | exploring genetic diversity and selection signatures in indigenous african cattle breeds |
| topic | genetics animal breeding |
| url | https://hdl.handle.net/10568/128739 |
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