Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity

Apoplastic ascorbate oxidases (AOs) play a critical role in reactive oxygen species (ROS)-mediated innate host immunity by regulating the apoplast redox state. To date, little is known about how apoplastic effectors of the rice blast fungus Magnaporthe oryzae modulate the apoplast redox state of ric...

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Main Authors: Hu, Jiexiong, Liu, Muxing, Zhang, Ao, Dai, Ying, Chen, Weizhong, Chen, Fang, Wang, Wenya, Shen, Danyu, Telebanco-Yanoria, Mary Jeanie, Ren, Bin, Zhang, Haifeng, Zhou, Huanbin, Zhou, Bo, Wang, Ping, Zhang, Zhengguang
Format: Journal Article
Language:Inglés
Published: Elsevier 2022
Subjects:
Online Access:https://hdl.handle.net/10568/126705
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author Hu, Jiexiong
Liu, Muxing
Zhang, Ao
Dai, Ying
Chen, Weizhong
Chen, Fang
Wang, Wenya
Shen, Danyu
Telebanco-Yanoria, Mary Jeanie
Ren, Bin
Zhang, Haifeng
Zhou, Huanbin
Zhou, Bo
Wang, Ping
Zhang, Zhengguang
author_browse Chen, Fang
Chen, Weizhong
Dai, Ying
Hu, Jiexiong
Liu, Muxing
Ren, Bin
Shen, Danyu
Telebanco-Yanoria, Mary Jeanie
Wang, Ping
Wang, Wenya
Zhang, Ao
Zhang, Haifeng
Zhang, Zhengguang
Zhou, Bo
Zhou, Huanbin
author_facet Hu, Jiexiong
Liu, Muxing
Zhang, Ao
Dai, Ying
Chen, Weizhong
Chen, Fang
Wang, Wenya
Shen, Danyu
Telebanco-Yanoria, Mary Jeanie
Ren, Bin
Zhang, Haifeng
Zhou, Huanbin
Zhou, Bo
Wang, Ping
Zhang, Zhengguang
author_sort Hu, Jiexiong
collection Repository of Agricultural Research Outputs (CGSpace)
description Apoplastic ascorbate oxidases (AOs) play a critical role in reactive oxygen species (ROS)-mediated innate host immunity by regulating the apoplast redox state. To date, little is known about how apoplastic effectors of the rice blast fungus Magnaporthe oryzae modulate the apoplast redox state of rice to subvert plant immunity. In this study, we demonstrated that M. oryzae MoAo1 is an AO that plays a role in virulence by modulating the apoplast redox status of rice cells. We showed that MoAo1 inhibits the activity of rice OsAO3 and OsAO4, which also regulate the apoplast redox status and plant immunity. In addition, we found that MoAo1, OsAO3, and OsAO4 all exhibit polymorphic variations whose varied interactions orchestrate pathogen virulence and rice immunity. Taken together, our results reveal a critical role for extracellular redox enzymes during rice blast infection and shed light on the importance of the apoplast redox state and its regulation in plant-pathogen interactions.
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spelling CGSpace1267052025-10-26T13:01:22Z Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity Hu, Jiexiong Liu, Muxing Zhang, Ao Dai, Ying Chen, Weizhong Chen, Fang Wang, Wenya Shen, Danyu Telebanco-Yanoria, Mary Jeanie Ren, Bin Zhang, Haifeng Zhou, Huanbin Zhou, Bo Wang, Ping Zhang, Zhengguang molecular genetics pathogenicity plant diseases fungal diseases pathogens plant breeding rice Apoplastic ascorbate oxidases (AOs) play a critical role in reactive oxygen species (ROS)-mediated innate host immunity by regulating the apoplast redox state. To date, little is known about how apoplastic effectors of the rice blast fungus Magnaporthe oryzae modulate the apoplast redox state of rice to subvert plant immunity. In this study, we demonstrated that M. oryzae MoAo1 is an AO that plays a role in virulence by modulating the apoplast redox status of rice cells. We showed that MoAo1 inhibits the activity of rice OsAO3 and OsAO4, which also regulate the apoplast redox status and plant immunity. In addition, we found that MoAo1, OsAO3, and OsAO4 all exhibit polymorphic variations whose varied interactions orchestrate pathogen virulence and rice immunity. Taken together, our results reveal a critical role for extracellular redox enzymes during rice blast infection and shed light on the importance of the apoplast redox state and its regulation in plant-pathogen interactions. 2022-08 2023-01-09T10:10:29Z 2023-01-09T10:10:29Z Journal Article https://hdl.handle.net/10568/126705 en Limited Access Elsevier Hu, Jiexiong, Liu, Muxing, Zhang, Ao, Dai, Ying, Chen, Weizhong, Chen, Fang, Wang, Wenya et al. 2022. Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apo-plast to modulate rice immunity. Molecular Plant 15(8):1347-1366.
spellingShingle molecular genetics
pathogenicity
plant diseases
fungal diseases
pathogens
plant breeding
rice
Hu, Jiexiong
Liu, Muxing
Zhang, Ao
Dai, Ying
Chen, Weizhong
Chen, Fang
Wang, Wenya
Shen, Danyu
Telebanco-Yanoria, Mary Jeanie
Ren, Bin
Zhang, Haifeng
Zhou, Huanbin
Zhou, Bo
Wang, Ping
Zhang, Zhengguang
Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title_full Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title_fullStr Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title_full_unstemmed Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title_short Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
title_sort co evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity
topic molecular genetics
pathogenicity
plant diseases
fungal diseases
pathogens
plant breeding
rice
url https://hdl.handle.net/10568/126705
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