Improving zinc and iron biofortification in wheat through genomics approaches

Globally, about 20% of calories (energy) come from wheat. In some countries, it is more than 70%. More than 2 billion people are at risk for zinc deficiency and even more, people are at risk of iron deficiency, nearly a quarter of all children underage group of 5 are physically and cognitively stunt...

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Main Authors: Wani, Shabir Hussain, Gaikwad, Kiran, Razzaq, Ali, Samantara, Kajal, Kumar, Manjeet, Velu, Govindan
Format: Journal Article
Language:Inglés
Published: Springer 2022
Subjects:
Online Access:https://hdl.handle.net/10568/126450
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author Wani, Shabir Hussain
Gaikwad, Kiran
Razzaq, Ali
Samantara, Kajal
Kumar, Manjeet
Velu, Govindan
author_browse Gaikwad, Kiran
Kumar, Manjeet
Razzaq, Ali
Samantara, Kajal
Velu, Govindan
Wani, Shabir Hussain
author_facet Wani, Shabir Hussain
Gaikwad, Kiran
Razzaq, Ali
Samantara, Kajal
Kumar, Manjeet
Velu, Govindan
author_sort Wani, Shabir Hussain
collection Repository of Agricultural Research Outputs (CGSpace)
description Globally, about 20% of calories (energy) come from wheat. In some countries, it is more than 70%. More than 2 billion people are at risk for zinc deficiency and even more, people are at risk of iron deficiency, nearly a quarter of all children underage group of 5 are physically and cognitively stunted, and lack of dietary zinc is a major contributing factor. Biofortified wheat with elevated levels of zinc and iron has several potential advantages as a delivery vehicle for micronutrients in the diets of resource-poor consumers who depend on cereal-based diets. The conventional breeding strategies have been successful in the introduction of novel alleles for grain Zn and Fe that led to the release of competitive Zn enriched wheat varieties in South Asia. The major challenge over the next few decades will be to maintain the rates of genetic gains for grain yield along with increased grain Zn/Fe concentration to meet the food and nutritional security challenges. Therefore, to remain competitive, the performance of Zn-enhanced lines/varieties must be equal or superior to that of current non-biofortified elite lines/varieties. Since both yield and Zn content are invisible and quantitatively inherited traits except few intermediate effect QTL regions identified for grain Zn, increased breeding efforts and new approaches are required to combine them at high frequency, ensuring that Zn levels are steadily increased to the required levels across the breeding pipelines. The current review article provides a comprehensive list of genomic regions for enhancing grain Zn and Fe concentrations in wheat including key candidate gene families such NAS, ZIP, VLT, ZIFL, and YSL. Implementing forward breeding by taking advantage of the rapid cycling trait pipeline approaches would simultaneously introgress high Zn and Fe QTL into the high Zn and normal elite lines, further increasing Zn and Fe concentrations.
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spelling CGSpace1264502025-12-08T09:54:28Z Improving zinc and iron biofortification in wheat through genomics approaches Wani, Shabir Hussain Gaikwad, Kiran Razzaq, Ali Samantara, Kajal Kumar, Manjeet Velu, Govindan chromosome mapping genomics iron wheat zinc Globally, about 20% of calories (energy) come from wheat. In some countries, it is more than 70%. More than 2 billion people are at risk for zinc deficiency and even more, people are at risk of iron deficiency, nearly a quarter of all children underage group of 5 are physically and cognitively stunted, and lack of dietary zinc is a major contributing factor. Biofortified wheat with elevated levels of zinc and iron has several potential advantages as a delivery vehicle for micronutrients in the diets of resource-poor consumers who depend on cereal-based diets. The conventional breeding strategies have been successful in the introduction of novel alleles for grain Zn and Fe that led to the release of competitive Zn enriched wheat varieties in South Asia. The major challenge over the next few decades will be to maintain the rates of genetic gains for grain yield along with increased grain Zn/Fe concentration to meet the food and nutritional security challenges. Therefore, to remain competitive, the performance of Zn-enhanced lines/varieties must be equal or superior to that of current non-biofortified elite lines/varieties. Since both yield and Zn content are invisible and quantitatively inherited traits except few intermediate effect QTL regions identified for grain Zn, increased breeding efforts and new approaches are required to combine them at high frequency, ensuring that Zn levels are steadily increased to the required levels across the breeding pipelines. The current review article provides a comprehensive list of genomic regions for enhancing grain Zn and Fe concentrations in wheat including key candidate gene families such NAS, ZIP, VLT, ZIFL, and YSL. Implementing forward breeding by taking advantage of the rapid cycling trait pipeline approaches would simultaneously introgress high Zn and Fe QTL into the high Zn and normal elite lines, further increasing Zn and Fe concentrations. 2022-08 2023-01-01T16:18:33Z 2023-01-01T16:18:33Z Journal Article https://hdl.handle.net/10568/126450 en Open Access application/pdf Springer Wani, S. H., Gaikwad, K., Razzaq, A., Samantara, K., Kumar, M., & Govindan, V. (2022). Improving Zinc and Iron Biofortification in Wheat through Genomics Approaches. Molecular Biology Reports, 49(8), 8007–8023. https://doi.org/10.1007/s11033-022-07326-z
spellingShingle chromosome mapping
genomics
iron
wheat
zinc
Wani, Shabir Hussain
Gaikwad, Kiran
Razzaq, Ali
Samantara, Kajal
Kumar, Manjeet
Velu, Govindan
Improving zinc and iron biofortification in wheat through genomics approaches
title Improving zinc and iron biofortification in wheat through genomics approaches
title_full Improving zinc and iron biofortification in wheat through genomics approaches
title_fullStr Improving zinc and iron biofortification in wheat through genomics approaches
title_full_unstemmed Improving zinc and iron biofortification in wheat through genomics approaches
title_short Improving zinc and iron biofortification in wheat through genomics approaches
title_sort improving zinc and iron biofortification in wheat through genomics approaches
topic chromosome mapping
genomics
iron
wheat
zinc
url https://hdl.handle.net/10568/126450
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