Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance

Proline is a proteinogenic amino acid synthesized from glutamate and ornithine. Pyrroline-5-carboxylate synthetase and pyrroline-5-carboxylate reductase are the two key enzymes involved in proline synthesis from glutamate. On the other hand, ornithine-δ-aminotransferase converts ornithine to pyrroli...

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Autores principales: Kavi Kishor, Polavarapu B., Suravajhala, Prashanth, Rathnagiri, P., Sreenivasulu, Nese
Formato: Journal Article
Lenguaje:Inglés
Publicado: Frontiers Media 2022
Materias:
Acceso en línea:https://hdl.handle.net/10568/126198
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author Kavi Kishor, Polavarapu B.
Suravajhala, Prashanth
Rathnagiri, P.
Sreenivasulu, Nese
author_browse Kavi Kishor, Polavarapu B.
Rathnagiri, P.
Sreenivasulu, Nese
Suravajhala, Prashanth
author_facet Kavi Kishor, Polavarapu B.
Suravajhala, Prashanth
Rathnagiri, P.
Sreenivasulu, Nese
author_sort Kavi Kishor, Polavarapu B.
collection Repository of Agricultural Research Outputs (CGSpace)
description Proline is a proteinogenic amino acid synthesized from glutamate and ornithine. Pyrroline-5-carboxylate synthetase and pyrroline-5-carboxylate reductase are the two key enzymes involved in proline synthesis from glutamate. On the other hand, ornithine-δ-aminotransferase converts ornithine to pyrroline 5-carboxylate (P5C), an intermediate in the synthesis of proline as well as glutamate. Both proline dehydrogenase and P5C dehydrogenase convert proline back to glutamate. Proline accumulation is widespread in response to environmental challenges such as high temperatures, and it is known to defend plants against unpropitious situations promoting plant growth and flowering. While proline accumulation is positively correlated with heat stress tolerance in some crops, it has detrimental consequences in others. Although it has been established that proline is a key osmolyte, its exact physiological function during heat stress and plant ontogeny remains unknown. Emerging evidence pointed out its role as an overriding molecule in alleviating high temperature stress (HTS) by quenching singlet oxygen and superoxide radicals. Proline cycle acts as a shuttle and the redox couple (NAD+/NADH, NADP+/NADPH) appears to be highly crucial for energy transfer among different cellular compartments during plant development, exposure to HTS conditions and also during the recovery of stress. In this review, the progress made in recent years regarding its involvement in heat stress tolerance is highlighted.
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spelling CGSpace1261982025-12-08T10:29:22Z Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance Kavi Kishor, Polavarapu B. Suravajhala, Prashanth Rathnagiri, P. Sreenivasulu, Nese stress protein content reactive oxygen species redox couple Proline is a proteinogenic amino acid synthesized from glutamate and ornithine. Pyrroline-5-carboxylate synthetase and pyrroline-5-carboxylate reductase are the two key enzymes involved in proline synthesis from glutamate. On the other hand, ornithine-δ-aminotransferase converts ornithine to pyrroline 5-carboxylate (P5C), an intermediate in the synthesis of proline as well as glutamate. Both proline dehydrogenase and P5C dehydrogenase convert proline back to glutamate. Proline accumulation is widespread in response to environmental challenges such as high temperatures, and it is known to defend plants against unpropitious situations promoting plant growth and flowering. While proline accumulation is positively correlated with heat stress tolerance in some crops, it has detrimental consequences in others. Although it has been established that proline is a key osmolyte, its exact physiological function during heat stress and plant ontogeny remains unknown. Emerging evidence pointed out its role as an overriding molecule in alleviating high temperature stress (HTS) by quenching singlet oxygen and superoxide radicals. Proline cycle acts as a shuttle and the redox couple (NAD+/NADH, NADP+/NADPH) appears to be highly crucial for energy transfer among different cellular compartments during plant development, exposure to HTS conditions and also during the recovery of stress. In this review, the progress made in recent years regarding its involvement in heat stress tolerance is highlighted. 2022-06-10 2022-12-21T14:26:42Z 2022-12-21T14:26:42Z Journal Article https://hdl.handle.net/10568/126198 en Open Access application/pdf Frontiers Media Kishor, PB Kavi, Prashanth Suravajhala, P. Rathnagiri, and Nese Sreenivasulu. "Intriguing role of proline in redox potential conferring high temperature stress tolerance." Frontiers in Plant Science 13 (2022).
spellingShingle stress
protein content
reactive oxygen species
redox couple
Kavi Kishor, Polavarapu B.
Suravajhala, Prashanth
Rathnagiri, P.
Sreenivasulu, Nese
Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title_full Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title_fullStr Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title_full_unstemmed Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title_short Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance
title_sort intriguing role of proline in redox potential conferring high temperature stress tolerance
topic stress
protein content
reactive oxygen species
redox couple
url https://hdl.handle.net/10568/126198
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AT rathnagirip intriguingroleofprolineinredoxpotentialconferringhightemperaturestresstolerance
AT sreenivasulunese intriguingroleofprolineinredoxpotentialconferringhightemperaturestresstolerance