Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania

Q fever is a zoonotic disease, resulting from infection with Coxiella burnetii. Infection in cattle can cause abortion and infertility, however, there is little epidemiological information regarding the disease in dairy cattle in Tanzania. Between July 2019 and October 2020, a serosurvey was conduct...

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Main Authors: Bwatota, S.F., Shirima, G.M., Hernandez-Castro, L.E., Bronsvoort, B.M. de C., Wheelhouse, N., Mengele, I.J., Motto, S.K., Komwihangilo, Daniel M., Lyatuu, Eliamoni T.R., Cook, Elizabeth A.J.
Format: Journal Article
Language:Inglés
Published: MDPI 2022
Subjects:
Online Access:https://hdl.handle.net/10568/125788
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author Bwatota, S.F.
Shirima, G.M.
Hernandez-Castro, L.E.
Bronsvoort, B.M. de C.
Wheelhouse, N.
Mengele, I.J.
Motto, S.K.
Komwihangilo, Daniel M.
Lyatuu, Eliamoni T.R.
Cook, Elizabeth A.J.
author_browse Bronsvoort, B.M. de C.
Bwatota, S.F.
Cook, Elizabeth A.J.
Hernandez-Castro, L.E.
Komwihangilo, Daniel M.
Lyatuu, Eliamoni T.R.
Mengele, I.J.
Motto, S.K.
Shirima, G.M.
Wheelhouse, N.
author_facet Bwatota, S.F.
Shirima, G.M.
Hernandez-Castro, L.E.
Bronsvoort, B.M. de C.
Wheelhouse, N.
Mengele, I.J.
Motto, S.K.
Komwihangilo, Daniel M.
Lyatuu, Eliamoni T.R.
Cook, Elizabeth A.J.
author_sort Bwatota, S.F.
collection Repository of Agricultural Research Outputs (CGSpace)
description Q fever is a zoonotic disease, resulting from infection with Coxiella burnetii. Infection in cattle can cause abortion and infertility, however, there is little epidemiological information regarding the disease in dairy cattle in Tanzania. Between July 2019 and October 2020, a serosurvey was conducted in six high dairy producing regions of Tanzania. Cattle sera were tested for antibodies to C. burnetii using an indirect enzyme-linked immunosorbent assay. A mixed effect logistic regression model identified risk factors associated with C. burnetii seropositivity. A total of 79 out of 2049 dairy cattle tested positive with an overall seroprevalence of 3.9% (95% CI 3.06–4.78) across the six regions with the highest seroprevalence in Tanga region (8.21%, 95% CI 6.0–10.89). Risk factors associated with seropositivity included: extensive feeding management (OR 2.77, 95% CI 1.25–3.77), and low precipitation below 1000 mm (OR 2.76, 95% 1.37–7.21). The disease seroprevalence is relatively low in the high dairy cattle producing regions of Tanzania. Due to the zoonotic potential of the disease, future efforts should employ a “One Health” approach to understand the epidemiology, and for interdisciplinary control to reduce the impacts on animal and human health.
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spelling CGSpace1257882025-12-08T10:29:22Z Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania Bwatota, S.F. Shirima, G.M. Hernandez-Castro, L.E. Bronsvoort, B.M. de C. Wheelhouse, N. Mengele, I.J. Motto, S.K. Komwihangilo, Daniel M. Lyatuu, Eliamoni T.R. Cook, Elizabeth A.J. animal diseases q fever dairying cattle Q fever is a zoonotic disease, resulting from infection with Coxiella burnetii. Infection in cattle can cause abortion and infertility, however, there is little epidemiological information regarding the disease in dairy cattle in Tanzania. Between July 2019 and October 2020, a serosurvey was conducted in six high dairy producing regions of Tanzania. Cattle sera were tested for antibodies to C. burnetii using an indirect enzyme-linked immunosorbent assay. A mixed effect logistic regression model identified risk factors associated with C. burnetii seropositivity. A total of 79 out of 2049 dairy cattle tested positive with an overall seroprevalence of 3.9% (95% CI 3.06–4.78) across the six regions with the highest seroprevalence in Tanga region (8.21%, 95% CI 6.0–10.89). Risk factors associated with seropositivity included: extensive feeding management (OR 2.77, 95% CI 1.25–3.77), and low precipitation below 1000 mm (OR 2.76, 95% 1.37–7.21). The disease seroprevalence is relatively low in the high dairy cattle producing regions of Tanzania. Due to the zoonotic potential of the disease, future efforts should employ a “One Health” approach to understand the epidemiology, and for interdisciplinary control to reduce the impacts on animal and human health. 2022-11-28 2022-12-06T08:15:39Z 2022-12-06T08:15:39Z Journal Article https://hdl.handle.net/10568/125788 en Open Access MDPI Bwatota, S.F., Shirima, G.M., Hernandez-Castro, L.E., Bronsvoort, B.M. de C., Wheelhouse, N., Mengele, I.J., Motto, S.K., Komwihangilo, D.M., Lyatuu, E. and Cook, E.A.J. 2022. Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania. Veterinary Sciences 9(12): 662.
spellingShingle animal diseases
q fever
dairying
cattle
Bwatota, S.F.
Shirima, G.M.
Hernandez-Castro, L.E.
Bronsvoort, B.M. de C.
Wheelhouse, N.
Mengele, I.J.
Motto, S.K.
Komwihangilo, Daniel M.
Lyatuu, Eliamoni T.R.
Cook, Elizabeth A.J.
Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title_full Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title_fullStr Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title_full_unstemmed Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title_short Seroprevalence and risk factors for Q fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania
title_sort seroprevalence and risk factors for q fever coxiella burnetii exposure in smallholder dairy cattle in tanzania
topic animal diseases
q fever
dairying
cattle
url https://hdl.handle.net/10568/125788
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