Lack of association between fluconazole susceptibility and ERG11 nucleotide polymorphisms in Cryptococcus neoformans clinical isolates from Uganda

Fluconazole is the drug of choice for cryptococcal meningitis (CM) monoprophylaxis in resource-limited settings such as Uganda. Emerging fluconazole resistance linked to mutations in the Cryptococcus neoformans ERG11 gene (CYP51) has been observed in clinical isolates. Currently, the single nucleoti...

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Bibliographic Details
Main Authors: Atim, Priscilla Belbir, Meya, David B., Gerlach, Elliot S., Muhanguzi, Dennis, Male, Allan, Kanamwanji, Benedict, Nielsen, Kirsten
Format: Journal Article
Language:Inglés
Published: MDPI 2022
Online Access:https://hdl.handle.net/10568/125776

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