Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava

Yellow-fleshed cassava root (YFCR) is processed into traditional products that may influence its bioactivities. In this study, the antioxidant and anti-hyperglycaemic activities of three traditional products (lafun, fufu and gari) from five genotypes (IITA-TMS-IBA070337, 182961, 182962, 182986, 1830...

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Main Authors: Kareem, B., Irondi, E.A., Alamu, Emmanuel Oladeji, Ajani, E.O., Abass, A., Adesokan, Michael, Parkes, Elizabeth Y., Maziya-Dixon, Busie
Format: Journal Article
Language:Inglés
Published: Frontiers Media 2022
Subjects:
Online Access:https://hdl.handle.net/10568/125201
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author Kareem, B.
Irondi, E.A.
Alamu, Emmanuel Oladeji
Ajani, E.O.
Abass, A.
Adesokan, Michael
Parkes, Elizabeth Y.
Maziya-Dixon, Busie
author_browse Abass, A.
Adesokan, Michael
Ajani, E.O.
Alamu, Emmanuel Oladeji
Irondi, E.A.
Kareem, B.
Maziya-Dixon, Busie
Parkes, Elizabeth Y.
author_facet Kareem, B.
Irondi, E.A.
Alamu, Emmanuel Oladeji
Ajani, E.O.
Abass, A.
Adesokan, Michael
Parkes, Elizabeth Y.
Maziya-Dixon, Busie
author_sort Kareem, B.
collection Repository of Agricultural Research Outputs (CGSpace)
description Yellow-fleshed cassava root (YFCR) is processed into traditional products that may influence its bioactivities. In this study, the antioxidant and anti-hyperglycaemic activities of three traditional products (lafun, fufu and gari) from five genotypes (IITA-TMS-IBA070337, 182961, 182962, 182986, 183044) of YFCR were evaluated. The YFCR genotypes were grown at the International Institute of Tropical Agriculture (IITA) research field, Ibadan. The bioactive constituents (total carotenoids, total phenolics, tannins and total flavonoids), antioxidant [2,2-azinobis (3-ethyl-benzothiazoline-6-sulfonic acid) radical cation (ABTS•+) and 1,1-diphenyl-2- picrylhydrazyl radical (DPPH•) scavenging capacities, and reducing power], and starch-digesting enzymes (a-amylase and a-glucosidase) inhibitory activities of the products were determined using standard laboratory methods. The glucose response of the products was assessed in human subjects. The concentrations of the bioactive constituents of the products from different genotypes varied significantly (p < 0.05). The ABTS•+ and DPPH• scavenging capacities and the reducing power of the products also differed significantly (p < 0.05), such that the lafun from IITA-TMS-IBA182962, IITA-TMS-IBA070337 and IITA-TMS-IBA070337 had the strongest ABTS•+ and DPPH• scavenging capacities, and reducing power, respectively. The a-amylase and a-glucosidase inhibitory activities of the three products differed significantly (p < 0.05), with the lafun from IITA-TMS-IBA070337 and IITA-TMS-IBA07033 having the strongest a-amylase and a-glucosidase inhibitory activity, respectively. Also, the lafun from IITA-TMS-182986 had the least glucose response, while the fufu from IITA-TMS-IBA070337 had the highest glucose response. Overall, the lafun from different genotypes of YFCR had the most potent antioxidant and starch-digesting enzymes inhibitory activities and the least glucose responses. Hence, lafun may be a promising dietary intervention targeting oxidative stress, hyperglycaemia, and their resultant type 2 diabetes.
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spelling CGSpace1252012025-12-08T10:29:22Z Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava Kareem, B. Irondi, E.A. Alamu, Emmanuel Oladeji Ajani, E.O. Abass, A. Adesokan, Michael Parkes, Elizabeth Y. Maziya-Dixon, Busie antioxidants bioactive food components enzymes cassava varieties processing genotypes Yellow-fleshed cassava root (YFCR) is processed into traditional products that may influence its bioactivities. In this study, the antioxidant and anti-hyperglycaemic activities of three traditional products (lafun, fufu and gari) from five genotypes (IITA-TMS-IBA070337, 182961, 182962, 182986, 183044) of YFCR were evaluated. The YFCR genotypes were grown at the International Institute of Tropical Agriculture (IITA) research field, Ibadan. The bioactive constituents (total carotenoids, total phenolics, tannins and total flavonoids), antioxidant [2,2-azinobis (3-ethyl-benzothiazoline-6-sulfonic acid) radical cation (ABTS•+) and 1,1-diphenyl-2- picrylhydrazyl radical (DPPH•) scavenging capacities, and reducing power], and starch-digesting enzymes (a-amylase and a-glucosidase) inhibitory activities of the products were determined using standard laboratory methods. The glucose response of the products was assessed in human subjects. The concentrations of the bioactive constituents of the products from different genotypes varied significantly (p < 0.05). The ABTS•+ and DPPH• scavenging capacities and the reducing power of the products also differed significantly (p < 0.05), such that the lafun from IITA-TMS-IBA182962, IITA-TMS-IBA070337 and IITA-TMS-IBA070337 had the strongest ABTS•+ and DPPH• scavenging capacities, and reducing power, respectively. The a-amylase and a-glucosidase inhibitory activities of the three products differed significantly (p < 0.05), with the lafun from IITA-TMS-IBA070337 and IITA-TMS-IBA07033 having the strongest a-amylase and a-glucosidase inhibitory activity, respectively. Also, the lafun from IITA-TMS-182986 had the least glucose response, while the fufu from IITA-TMS-IBA070337 had the highest glucose response. Overall, the lafun from different genotypes of YFCR had the most potent antioxidant and starch-digesting enzymes inhibitory activities and the least glucose responses. Hence, lafun may be a promising dietary intervention targeting oxidative stress, hyperglycaemia, and their resultant type 2 diabetes. 2022 2022-10-27T15:17:10Z 2022-10-27T15:17:10Z Journal Article https://hdl.handle.net/10568/125201 en Open Access application/pdf Frontiers Media Kareem, B., Irondi, E.A., Alamu, E.O., Ajani, E.O., Abass, A., Adesokan, M., ... & Maziya-Dixon, B. (2022). Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava. Frontiers in Nutrition, 9: 894843, 1-11.
spellingShingle antioxidants
bioactive food components
enzymes
cassava
varieties
processing
genotypes
Kareem, B.
Irondi, E.A.
Alamu, Emmanuel Oladeji
Ajani, E.O.
Abass, A.
Adesokan, Michael
Parkes, Elizabeth Y.
Maziya-Dixon, Busie
Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title_full Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title_fullStr Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title_full_unstemmed Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title_short Influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow-fleshed cassava
title_sort influence of traditional processing and genotypes on the antioxidant and antihyperglycaemic activities of yellow fleshed cassava
topic antioxidants
bioactive food components
enzymes
cassava
varieties
processing
genotypes
url https://hdl.handle.net/10568/125201
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