Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome

In recent years, Egyptian tilapia aquaculture has experienced mortality episodes during the summer months. The causative agents responsible for such mortalities have not been clearly identified. A total of 400 fish specimens were collected from affected tilapia farms within five Egyptian governorate...

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Autores principales: Ali, Shimaa E., Mahana, O., Mohan, Chadag V., Delamare-Deboutteville, Jerome, Elgendy, M.Y.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wiley 2022
Materias:
Acceso en línea:https://hdl.handle.net/10568/121159
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author Ali, Shimaa E.
Mahana, O.
Mohan, Chadag V.
Delamare-Deboutteville, Jerome
Elgendy, M.Y.
author_browse Ali, Shimaa E.
Delamare-Deboutteville, Jerome
Elgendy, M.Y.
Mahana, O.
Mohan, Chadag V.
author_facet Ali, Shimaa E.
Mahana, O.
Mohan, Chadag V.
Delamare-Deboutteville, Jerome
Elgendy, M.Y.
author_sort Ali, Shimaa E.
collection Repository of Agricultural Research Outputs (CGSpace)
description In recent years, Egyptian tilapia aquaculture has experienced mortality episodes during the summer months. The causative agents responsible for such mortalities have not been clearly identified. A total of 400 fish specimens were collected from affected tilapia farms within five Egyptian governorates. A total of 344 bacterial isolates were identified from the examined fish specimens. Bacterial isolates were grouped into seven genera based on API 20E results. The most prevalent pathogens were Aeromonas spp. (42%), Vibrio spp. (21%), and Streptococcus agalactiae (14.5%). Other emerging infections like, Plesiomonas shigelloides (10%), Staphyloccocus spp. (8%), Pseudomonas oryzihabitans, and Acinetobacter lwoffii (2.3%) were also detected. Sequence analysis of the 16S ribosomal RNA bacterial gene of some isolates, confirmed the phenotypic identification results. The analysis of antibiotic resistance genes revealed the presence of aac(6′)-Ib-cr (35.7%), blaCTX gene (23.8%), qnrS (19%), ampC (16.7%), floR (14.3%), sul1, tetA, and van.C1 (2.4%) genes in some isolates. The antimicrobia resistance gene, qac was reported in 46% of screened isolates. Bacterial strains showed variable virulence genes profiles. Aeromonas spp. harboured (act, gcat, aerA, lip, fla, and ser) genes. All Vibrio spp. possessed the hlyA gene, while cylE, hylB, and lmb genes, were detected in S. agalactiae strains. Our findings point to the possible role of the identified bacterial pathogens in tilapia summer mortality syndrome and highlight the risk of the irresponsible use of antibiotics on antimicrobial resistance in aquaculture.
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spelling CGSpace1211592024-11-07T09:51:39Z Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome Ali, Shimaa E. Mahana, O. Mohan, Chadag V. Delamare-Deboutteville, Jerome Elgendy, M.Y. antimicrobial resistance fish tilapia aquaculture In recent years, Egyptian tilapia aquaculture has experienced mortality episodes during the summer months. The causative agents responsible for such mortalities have not been clearly identified. A total of 400 fish specimens were collected from affected tilapia farms within five Egyptian governorates. A total of 344 bacterial isolates were identified from the examined fish specimens. Bacterial isolates were grouped into seven genera based on API 20E results. The most prevalent pathogens were Aeromonas spp. (42%), Vibrio spp. (21%), and Streptococcus agalactiae (14.5%). Other emerging infections like, Plesiomonas shigelloides (10%), Staphyloccocus spp. (8%), Pseudomonas oryzihabitans, and Acinetobacter lwoffii (2.3%) were also detected. Sequence analysis of the 16S ribosomal RNA bacterial gene of some isolates, confirmed the phenotypic identification results. The analysis of antibiotic resistance genes revealed the presence of aac(6′)-Ib-cr (35.7%), blaCTX gene (23.8%), qnrS (19%), ampC (16.7%), floR (14.3%), sul1, tetA, and van.C1 (2.4%) genes in some isolates. The antimicrobia resistance gene, qac was reported in 46% of screened isolates. Bacterial strains showed variable virulence genes profiles. Aeromonas spp. harboured (act, gcat, aerA, lip, fla, and ser) genes. All Vibrio spp. possessed the hlyA gene, while cylE, hylB, and lmb genes, were detected in S. agalactiae strains. Our findings point to the possible role of the identified bacterial pathogens in tilapia summer mortality syndrome and highlight the risk of the irresponsible use of antibiotics on antimicrobial resistance in aquaculture. 2022-12 2022-09-07T11:51:11Z 2022-09-07T11:51:11Z Journal Article https://hdl.handle.net/10568/121159 en Limited Access Wiley Ali, S.E., Mahana, O., Mohan, C.V., Delamare-Deboutteville, J. and Elgendy, M.Y. 2022. Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome. Journal of Fish Diseases 45(12): 1857–1871.
spellingShingle antimicrobial resistance
fish
tilapia
aquaculture
Ali, Shimaa E.
Mahana, O.
Mohan, Chadag V.
Delamare-Deboutteville, Jerome
Elgendy, M.Y.
Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title_full Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title_fullStr Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title_full_unstemmed Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title_short Genetic characterization and antimicrobial profiling of bacterial isolates collected from Nile tilapia (Oreochromis niloticus) affected by summer mortality syndrome
title_sort genetic characterization and antimicrobial profiling of bacterial isolates collected from nile tilapia oreochromis niloticus affected by summer mortality syndrome
topic antimicrobial resistance
fish
tilapia
aquaculture
url https://hdl.handle.net/10568/121159
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