Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya
Brucellosis, Q fever, and leptospirosis are priority zoonoses worldwide, yet their epidemiology is understudied, and studies investigating multiple pathogens are scarce. Therefore, we selected 316 small ruminants in irrigated, pastoral, and riverine settings in Tana River County and conducted repeat...
| Autores principales: | , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/121004 |
| _version_ | 1855524487401832448 |
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| author | Wainaina, Martin Lindahl, Johanna F. Dohoo, I. Mayer-Scholl, A. Roesel, Kristina Mbotha, Deborah Roesler, U. Grace, Delia Bett, Bernard K. Al Dahouk, S. |
| author_browse | Al Dahouk, S. Bett, Bernard K. Dohoo, I. Grace, Delia Lindahl, Johanna F. Mayer-Scholl, A. Mbotha, Deborah Roesel, Kristina Roesler, U. Wainaina, Martin |
| author_facet | Wainaina, Martin Lindahl, Johanna F. Dohoo, I. Mayer-Scholl, A. Roesel, Kristina Mbotha, Deborah Roesler, U. Grace, Delia Bett, Bernard K. Al Dahouk, S. |
| author_sort | Wainaina, Martin |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Brucellosis, Q fever, and leptospirosis are priority zoonoses worldwide, yet their epidemiology is understudied, and studies investigating multiple pathogens are scarce. Therefore, we selected 316 small ruminants in irrigated, pastoral, and riverine settings in Tana River County and conducted repeated sampling for animals that were initially seronegative between September 2014 and June 2015. We carried out serological and polymerase chain reaction tests and determined risk factors for exposure. The survey-weighted serological incidence rates were 1.8 (95% confidence intervals [CI]: 1.3–2.5) and 1.3 (95% CI: 0.7–2.3) cases per 100 animal-months at risk for Leptospira spp. and C. burnetii, respectively. We observed no seroconversions for Brucella spp. Animals from the irrigated setting had 6.83 (95% CI: 2.58–18.06, p-value = 0.01) higher odds of seropositivity to C. burnetii than those from riverine settings. Considerable co-exposure of animals to more than one zoonosis was also observed, with animals exposed to one zoonosis generally having 2.5 times higher odds of exposure to a second zoonosis. The higher incidence of C. burnetii and Leptospira spp. infections, which are understudied zoonoses in Kenya compared to Brucella spp., demonstrate the need for systematic prioritization of animal diseases to enable the appropriate allocation of resources. |
| format | Journal Article |
| id | CGSpace121004 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1210042025-12-08T10:29:22Z Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya Wainaina, Martin Lindahl, Johanna F. Dohoo, I. Mayer-Scholl, A. Roesel, Kristina Mbotha, Deborah Roesler, U. Grace, Delia Bett, Bernard K. Al Dahouk, S. zoonoses small ruminants sheep goats brucellosis leptospirosis q fever Brucellosis, Q fever, and leptospirosis are priority zoonoses worldwide, yet their epidemiology is understudied, and studies investigating multiple pathogens are scarce. Therefore, we selected 316 small ruminants in irrigated, pastoral, and riverine settings in Tana River County and conducted repeated sampling for animals that were initially seronegative between September 2014 and June 2015. We carried out serological and polymerase chain reaction tests and determined risk factors for exposure. The survey-weighted serological incidence rates were 1.8 (95% confidence intervals [CI]: 1.3–2.5) and 1.3 (95% CI: 0.7–2.3) cases per 100 animal-months at risk for Leptospira spp. and C. burnetii, respectively. We observed no seroconversions for Brucella spp. Animals from the irrigated setting had 6.83 (95% CI: 2.58–18.06, p-value = 0.01) higher odds of seropositivity to C. burnetii than those from riverine settings. Considerable co-exposure of animals to more than one zoonosis was also observed, with animals exposed to one zoonosis generally having 2.5 times higher odds of exposure to a second zoonosis. The higher incidence of C. burnetii and Leptospira spp. infections, which are understudied zoonoses in Kenya compared to Brucella spp., demonstrate the need for systematic prioritization of animal diseases to enable the appropriate allocation of resources. 2022-08-15 2022-08-30T10:22:09Z 2022-08-30T10:22:09Z Journal Article https://hdl.handle.net/10568/121004 en Open Access MDPI Wainaina, M., Lindahl, J.F., Dohoo, I., Mayer-Scholl, A., Roesel, K., Mbotha, D., Roesler, U., Grace, D., Bett, B. and Al Dahouk, S. 2022. Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya. Microorganisms 10(8): 1546. |
| spellingShingle | zoonoses small ruminants sheep goats brucellosis leptospirosis q fever Wainaina, Martin Lindahl, Johanna F. Dohoo, I. Mayer-Scholl, A. Roesel, Kristina Mbotha, Deborah Roesler, U. Grace, Delia Bett, Bernard K. Al Dahouk, S. Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title | Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title_full | Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title_fullStr | Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title_full_unstemmed | Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title_short | Longitudinal study of selected bacterial zoonoses in small ruminants in Tana River County, Kenya |
| title_sort | longitudinal study of selected bacterial zoonoses in small ruminants in tana river county kenya |
| topic | zoonoses small ruminants sheep goats brucellosis leptospirosis q fever |
| url | https://hdl.handle.net/10568/121004 |
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