Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus

Cassava (Manihot esculenta Crantz) is a crucial staple crop, and provides carbohydrate energy to more than half a billion people in the tropics. Cassava mosaic disease (CMD) is the most important disease of cassava in Africa. Since Sri Lanka Cassava Mosaic Virus (SLCMV) was first reported in South E...

Full description

Bibliographic Details
Main Authors: Thuy, C.T.L., López Lavalle, L.A., Vu, N.A., Hy, N.H., Nhan, P.T., Ceballos, H., Newby, J., Tung, N.B., Hein, N.T., Tuan, L.N., Hung, N., Hanh, N.T., Trang, D.T., Ha, P.T.T., Ham, L.H., Pham, X.H., Quynh, D.T.N., Rabbi, I.Y., Kulakow, Peter A., Zhang, X.
Format: Journal Article
Language:Inglés
Published: MDPI 2021
Subjects:
Online Access:https://hdl.handle.net/10568/118367
_version_ 1855543438093582336
author Thuy, C.T.L.
López Lavalle, L.A.
Vu, N.A.
Hy, N.H.
Nhan, P.T.
Ceballos, H.
Newby, J.
Tung, N.B.
Hein, N.T.
Tuan, L.N.
Hung, N.
Hanh, N.T.
Trang, D.T.
Ha, P.T.T.
Ham, L.H.
Pham, X.H.
Quynh, D.T.N.
Rabbi, I.Y.
Kulakow, Peter A.
Zhang, X.
author_browse Ceballos, H.
Ha, P.T.T.
Ham, L.H.
Hanh, N.T.
Hein, N.T.
Hung, N.
Hy, N.H.
Kulakow, Peter A.
López Lavalle, L.A.
Newby, J.
Nhan, P.T.
Pham, X.H.
Quynh, D.T.N.
Rabbi, I.Y.
Thuy, C.T.L.
Trang, D.T.
Tuan, L.N.
Tung, N.B.
Vu, N.A.
Zhang, X.
author_facet Thuy, C.T.L.
López Lavalle, L.A.
Vu, N.A.
Hy, N.H.
Nhan, P.T.
Ceballos, H.
Newby, J.
Tung, N.B.
Hein, N.T.
Tuan, L.N.
Hung, N.
Hanh, N.T.
Trang, D.T.
Ha, P.T.T.
Ham, L.H.
Pham, X.H.
Quynh, D.T.N.
Rabbi, I.Y.
Kulakow, Peter A.
Zhang, X.
author_sort Thuy, C.T.L.
collection Repository of Agricultural Research Outputs (CGSpace)
description Cassava (Manihot esculenta Crantz) is a crucial staple crop, and provides carbohydrate energy to more than half a billion people in the tropics. Cassava mosaic disease (CMD) is the most important disease of cassava in Africa. Since Sri Lanka Cassava Mosaic Virus (SLCMV) was first reported in South East Asia in 2015, establishing sustainable solutions to CMD has become a top priority for the cassava program at the International Center for Tropical Agriculture (CIAT) and its partners. In the present study, we screened two populations for CMD resistance: VNM142, 142 clones collected from farms throughout Vietnam, and CIAT102, 102 clones resistant to CMD or mites, which were introduced from CIAT. High broad-sense heritability was observed in all the trials (>0.80). From the population VNM142, eight clones showed high CMD resistance with CMD severity scores less than 2.0. Two resistant clones had the same DNA fingerprinting with the accessions CR63 (PER262 or TAI9) and KM57 (VNM8) in the genebank, respectively. To our knowledge, this is the first report of CMD resistance in the genebank at CIAT. We also used the two populations to validate the CMD markers S12_7926132 and S14_4626854. Both markers explained 51% of the population variance in the segregating population CIAT102, but only 11% in the diverse population VNM142. Thus, we concluded that the two CMD markers could not be used to select for CMD resistance in diverse populations, but could predict the CMD resistance in segregating populations when the susceptible parents do not have resistant marker alleles and the resistance of the CMD2 donors is confirmed.
format Journal Article
id CGSpace118367
institution CGIAR Consortium
language Inglés
publishDate 2021
publishDateRange 2021
publishDateSort 2021
publisher MDPI
publisherStr MDPI
record_format dspace
spelling CGSpace1183672025-12-08T09:54:28Z Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus Thuy, C.T.L. López Lavalle, L.A. Vu, N.A. Hy, N.H. Nhan, P.T. Ceballos, H. Newby, J. Tung, N.B. Hein, N.T. Tuan, L.N. Hung, N. Hanh, N.T. Trang, D.T. Ha, P.T.T. Ham, L.H. Pham, X.H. Quynh, D.T.N. Rabbi, I.Y. Kulakow, Peter A. Zhang, X. cassava diseases plant diseases marker-assisted selection Cassava (Manihot esculenta Crantz) is a crucial staple crop, and provides carbohydrate energy to more than half a billion people in the tropics. Cassava mosaic disease (CMD) is the most important disease of cassava in Africa. Since Sri Lanka Cassava Mosaic Virus (SLCMV) was first reported in South East Asia in 2015, establishing sustainable solutions to CMD has become a top priority for the cassava program at the International Center for Tropical Agriculture (CIAT) and its partners. In the present study, we screened two populations for CMD resistance: VNM142, 142 clones collected from farms throughout Vietnam, and CIAT102, 102 clones resistant to CMD or mites, which were introduced from CIAT. High broad-sense heritability was observed in all the trials (>0.80). From the population VNM142, eight clones showed high CMD resistance with CMD severity scores less than 2.0. Two resistant clones had the same DNA fingerprinting with the accessions CR63 (PER262 or TAI9) and KM57 (VNM8) in the genebank, respectively. To our knowledge, this is the first report of CMD resistance in the genebank at CIAT. We also used the two populations to validate the CMD markers S12_7926132 and S14_4626854. Both markers explained 51% of the population variance in the segregating population CIAT102, but only 11% in the diverse population VNM142. Thus, we concluded that the two CMD markers could not be used to select for CMD resistance in diverse populations, but could predict the CMD resistance in segregating populations when the susceptible parents do not have resistant marker alleles and the resistance of the CMD2 donors is confirmed. 2021 2022-03-14T11:42:29Z 2022-03-14T11:42:29Z Journal Article https://hdl.handle.net/10568/118367 en Open Access application/pdf MDPI Thuy, C.T.L., Lopez-Lavalle, L.A., Vu, N.A., Hy, N.H., Nhan, P.T., Ceballos, H., ... & Zhang, X. (2021). Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus. Agriculture, 11(9), 1-15.
spellingShingle cassava
diseases
plant diseases
marker-assisted selection
Thuy, C.T.L.
López Lavalle, L.A.
Vu, N.A.
Hy, N.H.
Nhan, P.T.
Ceballos, H.
Newby, J.
Tung, N.B.
Hein, N.T.
Tuan, L.N.
Hung, N.
Hanh, N.T.
Trang, D.T.
Ha, P.T.T.
Ham, L.H.
Pham, X.H.
Quynh, D.T.N.
Rabbi, I.Y.
Kulakow, Peter A.
Zhang, X.
Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title_full Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title_fullStr Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title_full_unstemmed Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title_short Identifying new resistance to Cassava Mosaic Disease and validating markers for the CMD2 locus
title_sort identifying new resistance to cassava mosaic disease and validating markers for the cmd2 locus
topic cassava
diseases
plant diseases
marker-assisted selection
url https://hdl.handle.net/10568/118367
work_keys_str_mv AT thuyctl identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT lopezlavallela identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT vuna identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT hynh identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT nhanpt identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT ceballosh identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT newbyj identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT tungnb identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT heinnt identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT tuanln identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT hungn identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT hanhnt identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT trangdt identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT haptt identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT hamlh identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT phamxh identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT quynhdtn identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT rabbiiy identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT kulakowpetera identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus
AT zhangx identifyingnewresistancetocassavamosaicdiseaseandvalidatingmarkersforthecmd2locus