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Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus

The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes invo...

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Main Authors: Downing, T., Lynn, D.J., Connel, S., Lloyd, A.T., Bhuiyan, A.K.F.H., Silva, P., Naqvi, A.N., Sanfo, R., Sow, R.S., Overseas Development Institute, Hanotte, Olivier H., O'Farrelly, C.O., Bradley, D.
Format: Journal Article
Language:Inglés
Published: Springer 2009
Subjects:
chickens
animal diseases
Online Access:https://hdl.handle.net/10568/1176
Summary:The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms.

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