Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus

The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes invo...

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Autores principales: Downing, T., Lynn, D.J., Connel, S., Lloyd, A.T., Bhuiyan, A.K.F.H., Silva, P., Naqvi, A.N., Sanfo, R., Sow, R.S., Overseas Development Institute, Hanotte, Olivier H., O'Farrelly, C.O., Bradley, D.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2009
Materias:
Acceso en línea:https://hdl.handle.net/10568/1176
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author Downing, T.
Lynn, D.J.
Connel, S.
Lloyd, A.T.
Bhuiyan, A.K.F.H.
Silva, P.
Naqvi, A.N.
Sanfo, R.
Sow, R.S.
Overseas Development Institute
Hanotte, Olivier H.
O'Farrelly, C.O.
Bradley, D.
author_browse Bhuiyan, A.K.F.H.
Bradley, D.
Connel, S.
Downing, T.
Hanotte, Olivier H.
Lloyd, A.T.
Lynn, D.J.
Naqvi, A.N.
O'Farrelly, C.O.
Overseas Development Institute
Sanfo, R.
Silva, P.
Sow, R.S.
author_facet Downing, T.
Lynn, D.J.
Connel, S.
Lloyd, A.T.
Bhuiyan, A.K.F.H.
Silva, P.
Naqvi, A.N.
Sanfo, R.
Sow, R.S.
Overseas Development Institute
Hanotte, Olivier H.
O'Farrelly, C.O.
Bradley, D.
author_sort Downing, T.
collection Repository of Agricultural Research Outputs (CGSpace)
description The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms.
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spelling CGSpace11762024-05-01T08:17:42Z Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus Downing, T. Lynn, D.J. Connel, S. Lloyd, A.T. Bhuiyan, A.K.F.H. Silva, P. Naqvi, A.N. Sanfo, R. Sow, R.S. Overseas Development Institute Hanotte, Olivier H. O'Farrelly, C.O. Bradley, D. chickens animal diseases The comparative analysis of genome sequences emerging for several avian species with the fully sequenced chicken genome enables the genome-wide investigation of selective processes in functionally important chicken genes. In particular, because of pathogenic challenges it is expected that genes involved in the chicken immune system are subject to particularly strong adaptive pressure. Signatures of selection detected by inter-species comparison may then be investigated at the population level in global chicken populations to highlight potentially relevant functional polymorphisms. 2009-12 2010-04-11T20:02:01Z 2010-04-11T20:02:01Z Journal Article https://hdl.handle.net/10568/1176 en Open Access Springer Downing, T.; Lynn, D.J.; Connell, S.; Lloyd, A.T.; Bhuiyan, A.K.F.H.; Silva, P.; Naqvi, A.N.; Sanfo, R.; Sow, R-S.; Podisi, B.; Hanotte, O.; O'Farelly, C.O.; Bradley, D. 2009. Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus. BMC Evolutionary Biology. 9:136-149.
spellingShingle chickens
animal diseases
Downing, T.
Lynn, D.J.
Connel, S.
Lloyd, A.T.
Bhuiyan, A.K.F.H.
Silva, P.
Naqvi, A.N.
Sanfo, R.
Sow, R.S.
Overseas Development Institute
Hanotte, Olivier H.
O'Farrelly, C.O.
Bradley, D.
Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title_full Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title_fullStr Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title_full_unstemmed Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title_short Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
title_sort evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus
topic chickens
animal diseases
url https://hdl.handle.net/10568/1176
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