Systematic determination of TCR-antigen and peptide-MHC binding kinetics among field variants of a Theileria parva polymorphic CTL epitope

CTLs are known to contribute to immunity toward Theileria parva, the causative agent of East Coast fever. The Tp967-75 CTL epitope from the Muguga strain of T. parva is polymorphic in other parasite strains. Identifying the amino acids important for MHC class I binding, as well as TCR recognition of...

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Bibliographic Details
Main Authors: Svitek, Nicholas, Saya, Rosemary, Houshuang Zhang, Nene, Vishvanath M., Steinaa, Lucilla
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2022
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Online Access:https://hdl.handle.net/10568/117535

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