Panache: a web browser-based viewer for linearized pangenomes

Pangenomics evolved since its first applications on bacteria, extending from the study of genes for a given population to the study of all of its sequences available. While multiple methods are being developed to construct pangenomes in eukaryotic species there is still a gap for efficient and user-...

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Bibliographic Details
Main Authors: Durant, Éloi, Sabot, François, Conte, Matthieu, Rouard, Mathieu
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2021
Subjects:
Online Access:https://hdl.handle.net/10568/115324
Description
Summary:Pangenomics evolved since its first applications on bacteria, extending from the study of genes for a given population to the study of all of its sequences available. While multiple methods are being developed to construct pangenomes in eukaryotic species there is still a gap for efficient and user-friendly visualization tools. Emerging graph representations come with their own challenges, and linearity remains a suitable option for user-friendliness.We introduce Panache, a tool for the visualization and exploration of linear representations of gene-based and sequence-based pangenomes. It uses a layout similar to genome browsers to display presence absence variations and additional tracks along a linear axis with a pangenomics perspective.Panache is available at github.com/SouthGreenPlatform/panache under the MIT License.