The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research
Clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) genome editing technology has dramatically influenced swine research by enabling the production of high-quality disease-resistant pig breeds, thus improving yields. Additionally, CRISPR/Cas9 has been...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/113738 |
| _version_ | 1855523232502775808 |
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| author | Zhang, J. Khazalwa, Emmanuel M. Abkallo, Hussein M. Zhou, Y. Nie, X. Ruan, J. Zhao, C. Wang, J. Xu, J. Li, X. Zhao, S. Zuo, E. Steinaa, Lucilla Xie, S. |
| author_browse | Abkallo, Hussein M. Khazalwa, Emmanuel M. Li, X. Nie, X. Ruan, J. Steinaa, Lucilla Wang, J. Xie, S. Xu, J. Zhang, J. Zhao, C. Zhao, S. Zhou, Y. Zuo, E. |
| author_facet | Zhang, J. Khazalwa, Emmanuel M. Abkallo, Hussein M. Zhou, Y. Nie, X. Ruan, J. Zhao, C. Wang, J. Xu, J. Li, X. Zhao, S. Zuo, E. Steinaa, Lucilla Xie, S. |
| author_sort | Zhang, J. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) genome editing technology has dramatically influenced swine research by enabling the production of high-quality disease-resistant pig breeds, thus improving yields. Additionally, CRISPR/Cas9 has been used extensively in pigs as one of the tools in biomedical research. In this review, we present the advancements of the CRISPR/Cas9 system in swine research such as animal breeding, vaccine development, xenotransplantation, and disease modelling. We also highlight the current challenges and some potential applications of the CRISPR/Cas9 technologies. |
| format | Journal Article |
| id | CGSpace113738 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace1137382025-08-15T13:21:42Z The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research Zhang, J. Khazalwa, Emmanuel M. Abkallo, Hussein M. Zhou, Y. Nie, X. Ruan, J. Zhao, C. Wang, J. Xu, J. Li, X. Zhao, S. Zuo, E. Steinaa, Lucilla Xie, S. swine research genomics crispr Clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) genome editing technology has dramatically influenced swine research by enabling the production of high-quality disease-resistant pig breeds, thus improving yields. Additionally, CRISPR/Cas9 has been used extensively in pigs as one of the tools in biomedical research. In this review, we present the advancements of the CRISPR/Cas9 system in swine research such as animal breeding, vaccine development, xenotransplantation, and disease modelling. We also highlight the current challenges and some potential applications of the CRISPR/Cas9 technologies. 2021-05 2021-05-19T08:39:40Z 2021-05-19T08:39:40Z Journal Article https://hdl.handle.net/10568/113738 en Limited Access Elsevier Zhang, J., Khazalwa, E.M., Abkallo, H.M., Zhou, Y., Nie, X., Ruan, J., Zhao, C., Wang, J., Xu, J., Li, X., Zhao, S., Zuo, E., Steinaa, L. and Xie, S. 2021. The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research. Journal of Genetics and Genomics 48(5): 347–360. |
| spellingShingle | swine research genomics crispr Zhang, J. Khazalwa, Emmanuel M. Abkallo, Hussein M. Zhou, Y. Nie, X. Ruan, J. Zhao, C. Wang, J. Xu, J. Li, X. Zhao, S. Zuo, E. Steinaa, Lucilla Xie, S. The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title | The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title_full | The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title_fullStr | The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title_full_unstemmed | The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title_short | The advancements, challenges and future implications of the CRISPR/Cas9 system in swine research |
| title_sort | advancements challenges and future implications of the crispr cas9 system in swine research |
| topic | swine research genomics crispr |
| url | https://hdl.handle.net/10568/113738 |
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