Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam
Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum sa...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/113066 |
| _version_ | 1855528137938436096 |
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| author | Long Pham-Thanh Thang Nguyen-Tien Magnusson, Ulf Vuong Bui Nghia Anh Bui-Ngoc Duy Le-Thanh Lundkvist, Å. Minh Can-Xuan Thuy Nguyen-Thi Thu Hau Vu-Thi Bich Hu Suk Lee Hung Nguyen-Viet Lindahl, Johanna F. |
| author_browse | Anh Bui-Ngoc Duy Le-Thanh Hau Vu-Thi Bich Hu Suk Lee Hung Nguyen-Viet Lindahl, Johanna F. Long Pham-Thanh Lundkvist, Å. Magnusson, Ulf Minh Can-Xuan Thang Nguyen-Tien Thuy Nguyen-Thi Thu Vuong Bui Nghia |
| author_facet | Long Pham-Thanh Thang Nguyen-Tien Magnusson, Ulf Vuong Bui Nghia Anh Bui-Ngoc Duy Le-Thanh Lundkvist, Å. Minh Can-Xuan Thuy Nguyen-Thi Thu Hau Vu-Thi Bich Hu Suk Lee Hung Nguyen-Viet Lindahl, Johanna F. |
| author_sort | Long Pham-Thanh |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum samples from 221 households in six districts of Hanoi were analyzed by a competitive enzyme-linked immunosorbent assay (cELISA) for antibodies to the pr-E protein of West Nile virus and other flaviviruses due to cross-reactivity. The overall flavivirus seroprevalence in the dog population was 70.7% (95% CI = 66.4–74.8%). At the animal level, significant associations between seropositive dogs and district location, age, breed and keeping practice were determined. At the household level, the major risk factors were rural and peri-urban locations, presence of pigs, coil burning and households without mosquito-borne disease experience (p < 0.05). Mosquito control by using larvicides or electric traps could lower seropositivity, but other measures did not contribute to significant risk mitigation of flavivirus exposure in dogs. These results will support better control of mosquito-borne diseases in Hanoi, and they indicate that dogs can be used as sentinels for flavivirus exposure. |
| format | Journal Article |
| id | CGSpace113066 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | CGSpace1130662025-08-15T13:22:06Z Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam Long Pham-Thanh Thang Nguyen-Tien Magnusson, Ulf Vuong Bui Nghia Anh Bui-Ngoc Duy Le-Thanh Lundkvist, Å. Minh Can-Xuan Thuy Nguyen-Thi Thu Hau Vu-Thi Bich Hu Suk Lee Hung Nguyen-Viet Lindahl, Johanna F. dogs flavivirus disease control Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum samples from 221 households in six districts of Hanoi were analyzed by a competitive enzyme-linked immunosorbent assay (cELISA) for antibodies to the pr-E protein of West Nile virus and other flaviviruses due to cross-reactivity. The overall flavivirus seroprevalence in the dog population was 70.7% (95% CI = 66.4–74.8%). At the animal level, significant associations between seropositive dogs and district location, age, breed and keeping practice were determined. At the household level, the major risk factors were rural and peri-urban locations, presence of pigs, coil burning and households without mosquito-borne disease experience (p < 0.05). Mosquito control by using larvicides or electric traps could lower seropositivity, but other measures did not contribute to significant risk mitigation of flavivirus exposure in dogs. These results will support better control of mosquito-borne diseases in Hanoi, and they indicate that dogs can be used as sentinels for flavivirus exposure. 2021-03-19 2021-03-22T14:24:19Z 2021-03-22T14:24:19Z Journal Article https://hdl.handle.net/10568/113066 en Open Access MDPI Long Pham-Thanh, Thang Nguyen-Tien, Magnusson, U., Vuong Bui-Nghia, Anh Bui-Ngoc, Duy Le-Thanh, Lundkvist, Å., Minh Can-Xuan, Thuy Nguyen-Thi Thu, Hau Vu-Thi Bich, Hu Suk Lee, Hung Nguyen-Viet and Lindahl, J. 2021. Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam. Viruses 13(3): 507. |
| spellingShingle | dogs flavivirus disease control Long Pham-Thanh Thang Nguyen-Tien Magnusson, Ulf Vuong Bui Nghia Anh Bui-Ngoc Duy Le-Thanh Lundkvist, Å. Minh Can-Xuan Thuy Nguyen-Thi Thu Hau Vu-Thi Bich Hu Suk Lee Hung Nguyen-Viet Lindahl, Johanna F. Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title | Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title_full | Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title_fullStr | Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title_full_unstemmed | Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title_short | Dogs as sentinels for flavivirus exposure in urban, peri-urban and rural Hanoi, Vietnam |
| title_sort | dogs as sentinels for flavivirus exposure in urban peri urban and rural hanoi vietnam |
| topic | dogs flavivirus disease control |
| url | https://hdl.handle.net/10568/113066 |
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