The management and economics of East Coast fever

This book chapter tackles the management and economics of east coast fever. At about the time of ILRAD's establishment in 1973, a vaccination procedure was being developed at the East African Veterinary Research Organization (EAVRO) at Muguga, Kenya. The infection-and-treatment method (ITM) is an im...

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Autores principales: Toye, Philip G., Kiara, Henry K., Ole-MoiYoi, Onesmo, Enahoro, Dolapo K., Rich, Karl M.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: CAB International 2020
Materias:
Acceso en línea:https://hdl.handle.net/10568/110748
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author Toye, Philip G.
Kiara, Henry K.
Ole-MoiYoi, Onesmo
Enahoro, Dolapo K.
Rich, Karl M.
author_browse Enahoro, Dolapo K.
Kiara, Henry K.
Ole-MoiYoi, Onesmo
Rich, Karl M.
Toye, Philip G.
author_facet Toye, Philip G.
Kiara, Henry K.
Ole-MoiYoi, Onesmo
Enahoro, Dolapo K.
Rich, Karl M.
author_sort Toye, Philip G.
collection Repository of Agricultural Research Outputs (CGSpace)
description This book chapter tackles the management and economics of east coast fever. At about the time of ILRAD's establishment in 1973, a vaccination procedure was being developed at the East African Veterinary Research Organization (EAVRO) at Muguga, Kenya. The infection-and-treatment method (ITM) is an immunization procedure against ECF. It involves inoculation of live sporozoites of T. parva, usually in the form of a semi-purified homogenate of T. parva-infected ticks, combined with simultaneous treatment with a dose of a long-acting formulation of the antibiotic oxytetracycline. Whilst safe and very effective when administered correctly, production and delivery of this live ECF vaccine is complicated, expensive and time consuming, and at the time of ILRAD's founding, there were doubts as to whether such a procedure was commercially viable. The future for ILRI in the pathology and immunoparasitology of theileriosis will be guided by the vaccine, balanced against the evolving prospects for a subunit vaccine. The future in the epidemiology and economics of ECF management will be developing and evaluating current or novel control methods.
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spelling CGSpace1107482023-12-08T19:36:04Z The management and economics of East Coast fever Toye, Philip G. Kiara, Henry K. Ole-MoiYoi, Onesmo Enahoro, Dolapo K. Rich, Karl M. livestock east coast fever animal diseases This book chapter tackles the management and economics of east coast fever. At about the time of ILRAD's establishment in 1973, a vaccination procedure was being developed at the East African Veterinary Research Organization (EAVRO) at Muguga, Kenya. The infection-and-treatment method (ITM) is an immunization procedure against ECF. It involves inoculation of live sporozoites of T. parva, usually in the form of a semi-purified homogenate of T. parva-infected ticks, combined with simultaneous treatment with a dose of a long-acting formulation of the antibiotic oxytetracycline. Whilst safe and very effective when administered correctly, production and delivery of this live ECF vaccine is complicated, expensive and time consuming, and at the time of ILRAD's founding, there were doubts as to whether such a procedure was commercially viable. The future for ILRI in the pathology and immunoparasitology of theileriosis will be guided by the vaccine, balanced against the evolving prospects for a subunit vaccine. The future in the epidemiology and economics of ECF management will be developing and evaluating current or novel control methods. 2020-01 2021-01-07T08:45:31Z 2021-01-07T08:45:31Z Book Chapter https://hdl.handle.net/10568/110748 en https://hdl.handle.net/10568/108972 Open Access application/pdf CAB International Toye, P., Kiara, H., Ole-MoiYoi, O., Enahoro, D. and Rich, K. 2020. The management and economics of East Coast fever. IN: McIntire, J. and Grace, D. (eds), The impact of the International Livestock Research Institute. Nairobi, Kenya: ILRI and Wallingford, UK: CABI: 239-273.
spellingShingle livestock
east coast fever
animal diseases
Toye, Philip G.
Kiara, Henry K.
Ole-MoiYoi, Onesmo
Enahoro, Dolapo K.
Rich, Karl M.
The management and economics of East Coast fever
title The management and economics of East Coast fever
title_full The management and economics of East Coast fever
title_fullStr The management and economics of East Coast fever
title_full_unstemmed The management and economics of East Coast fever
title_short The management and economics of East Coast fever
title_sort management and economics of east coast fever
topic livestock
east coast fever
animal diseases
url https://hdl.handle.net/10568/110748
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