European landrace diversity for common bean biofortification: a genome-wide association study

Mineral deficiencies represent a global challenge that needs to be urgently addressed. An adequate intake of iron and zinc results in a balanced diet that reduces chances of impairment of many metabolic processes that can lead to clinical consequences. In plants, bioavailability of such nutrients is...

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Autores principales: Caproni, Leonardo, Raggi, Lorenzo, Talsma, Elise F., Wenzl, Peter, Negri, Valeria
Formato: Journal Article
Lenguaje:Inglés
Publicado: Springer 2020
Materias:
Acceso en línea:https://hdl.handle.net/10568/110300
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author Caproni, Leonardo
Raggi, Lorenzo
Talsma, Elise F.
Wenzl, Peter
Negri, Valeria
author_browse Caproni, Leonardo
Negri, Valeria
Raggi, Lorenzo
Talsma, Elise F.
Wenzl, Peter
author_facet Caproni, Leonardo
Raggi, Lorenzo
Talsma, Elise F.
Wenzl, Peter
Negri, Valeria
author_sort Caproni, Leonardo
collection Repository of Agricultural Research Outputs (CGSpace)
description Mineral deficiencies represent a global challenge that needs to be urgently addressed. An adequate intake of iron and zinc results in a balanced diet that reduces chances of impairment of many metabolic processes that can lead to clinical consequences. In plants, bioavailability of such nutrients is reduced by presence of compounds such as phytic acid, that can chelate minerals and reduce their absorption. Biofortification of common bean (Phaseolus vulgaris L.) represents an important strategy to reduce mineral deficiencies, especially in areas of the world where this crop plays a key role in the diet. In this study, a panel of diversity encompassing 192 homozygous genotypes, was screened for iron, zinc and phytate seed content. Results indicate a broad variation of these traits and allowed the identification of accessions reasonably carrying favourable trait combinations. A significant association between zinc seed content and some molecular SNP markers co-located on the common bean Pv01 chromosome was detected by means of genome-wide association analysis. The gene Phvul001G233500, encoding for an E3 ubiquitin-protein ligase, is proposed to explain detected associations. This result represents a preliminary evidence that can foster future research aiming at understanding the genetic mechanisms behind zinc accumulation in beans.
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spelling CGSpace1103002025-11-11T19:06:08Z European landrace diversity for common bean biofortification: a genome-wide association study Caproni, Leonardo Raggi, Lorenzo Talsma, Elise F. Wenzl, Peter Negri, Valeria razas indigenas land races biodiversidad biodiversity recursos geneticos genetic resources frijol beans marcadores geneticos genetic markers Mineral deficiencies represent a global challenge that needs to be urgently addressed. An adequate intake of iron and zinc results in a balanced diet that reduces chances of impairment of many metabolic processes that can lead to clinical consequences. In plants, bioavailability of such nutrients is reduced by presence of compounds such as phytic acid, that can chelate minerals and reduce their absorption. Biofortification of common bean (Phaseolus vulgaris L.) represents an important strategy to reduce mineral deficiencies, especially in areas of the world where this crop plays a key role in the diet. In this study, a panel of diversity encompassing 192 homozygous genotypes, was screened for iron, zinc and phytate seed content. Results indicate a broad variation of these traits and allowed the identification of accessions reasonably carrying favourable trait combinations. A significant association between zinc seed content and some molecular SNP markers co-located on the common bean Pv01 chromosome was detected by means of genome-wide association analysis. The gene Phvul001G233500, encoding for an E3 ubiquitin-protein ligase, is proposed to explain detected associations. This result represents a preliminary evidence that can foster future research aiming at understanding the genetic mechanisms behind zinc accumulation in beans. 2020 2020-11-25T16:40:46Z 2020-11-25T16:40:46Z Journal Article https://hdl.handle.net/10568/110300 en Open Access application/pdf Springer Caproni, L.; Raggi, L.; Talsma, E.F.; Wenzl, P.; Negri, V. 2020. European landrace diversity for common bean biofortification: a genome-wide association study. Scientific Report 10 (19775) https://doi.org/10.1038/s41598-020-76417-3
spellingShingle razas indigenas
land races
biodiversidad
biodiversity
recursos geneticos
genetic resources
frijol
beans
marcadores geneticos
genetic markers
Caproni, Leonardo
Raggi, Lorenzo
Talsma, Elise F.
Wenzl, Peter
Negri, Valeria
European landrace diversity for common bean biofortification: a genome-wide association study
title European landrace diversity for common bean biofortification: a genome-wide association study
title_full European landrace diversity for common bean biofortification: a genome-wide association study
title_fullStr European landrace diversity for common bean biofortification: a genome-wide association study
title_full_unstemmed European landrace diversity for common bean biofortification: a genome-wide association study
title_short European landrace diversity for common bean biofortification: a genome-wide association study
title_sort european landrace diversity for common bean biofortification a genome wide association study
topic razas indigenas
land races
biodiversidad
biodiversity
recursos geneticos
genetic resources
frijol
beans
marcadores geneticos
genetic markers
url https://hdl.handle.net/10568/110300
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